Cytotoxicity and ultrastructural changes in H9c2(2-1) cells treated with pavetamine, a novel polyamine

Toxicon

Volumn 55, Issue 1, 2010, Pages 12-19

  Ellis, C E ^a,b   Naicker, D ^a,b   Basson, K M ^a   Botha, C J ^b   Meintjes, R A ^b   Schultz, R A ^a  

^a ONDERSTEPOORT VETERINARY INSTITUTE   (South Africa)

^b UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

Cardiotoxicity; Gousiekte; H9c2(2 1) cell line; Mitochondria; Pavetamine; Polyamine

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 5,5',6,6' TETRACHLORO 1,1',3,3' TETRAETHYL IMIDACARBOCYANINE IODIDE; CYCLOSPORIN A; FLUORESCENT DYE; LACTATE DEHYDROGENASE; PAVETAMINE; POLYAMINE; TETRAMETHYLRHODAMINE METHYL ESTER PERCHLORATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL NUCLEUS; CELL SURVIVAL; CELL TRANSFORMATION; CELL ULTRASTRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; EMBRYO; ENZYME RELEASE; FRAGMENTATION REACTION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART MUSCLE NECROSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CELL DEATH; CELL LINE; CYTOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCYTES, CARDIAC; NECROSIS; PLANT LEAVES; POLYAMINES; RATS; RUBIACEAE; SARCOPLASMIC RETICULUM; TIME FACTORS;

EID: 70649087173     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.11.017     Document Type: Article

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