Poisoning of sheep by seeds of Crotalaria retusa: Acquired resistance by continuous administration of low doses

Toxicon

Volumn 55, Issue 1, 2010, Pages 28-32

  Anjos, Bruno Leite ^a   Nobre, Verônica M T ^a   Dantas, Antônio F M ^a   Medeiros, Rosane M T ^a   Oliveira Neto, Temístocles S ^a   Molyneux, Russell J ^b   Riet Correa, Franklin ^a  

^a FEDERAL UNIVERSITY OF CAMPINA GRANDE   (Brazil)

^b WESTERN REGIONAL RESEARCH CENTER   (United States)

Author keywords

Acute poisoning; Chronic poisoning; Monocrotaline; Pyrrolizidine alkaloids; Seeds; Sheep resistance

Indexed keywords

ASPARTATE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; MONOCROTALINE;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC TOXICITY; CLINICAL FEATURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROTALARIA; CROTALARIA RETUSA; DRY WEIGHT; ENZYME ACTIVITY; INDUCED RESISTANCE; INGESTION; INTOXICATION; LIVER FIBROSIS; LIVER NECROSIS; LIVER TOXICITY; MEGALOCYTOSIS; NONHUMAN; PLANT SEED; PRIORITY JOURNAL; SHEEP DISEASE; TOXICITY TESTING;

ANIMAL FEED; ANIMALS; BRAZIL; CROTALARIA; DRUG TOLERANCE; INTUBATION, GASTROINTESTINAL; LIVER; LIVER CIRRHOSIS; MAGNETIC RESONANCE SPECTROSCOPY; MONOCROTALINE; NECROSIS; PLANT POISONING; PYRROLIZIDINE ALKALOIDS; SEEDS; SHEEP DISEASES; SHEEP, DOMESTIC;

CROTALARIA RETUSA; OVIS ARIES;

EID: 70649085071     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.06.028     Document Type: Article

References (30)

1. Anonymous. Toxaemic jaundice of sheep: phytogenous chronic copper poisoning, Heliotrope poisoning, and hepatogenous chronic copper poisoning. Aust. Vet. J. 32 (1956) 229-235
2. Bull L.B., Dick A.T., Keast J.C., and Edgar G. An experimental investigation of the hepatotoxic and other effects on sheep of consumption of Heliotropium europaeum L.: Heliotrope poisoning of sheep. Aust. J. Agric. Res. 7 (1956) 281-332
3. Cheeke P.P. Toxicity and metabolism of pyrrolizidine alkaloids. J. Anim Sci. 66 (1988) 2343-2350
4. Cheeke P.R. A review of the functional and evolutionary roles of the liver in the detoxification of poisonous plants, with special reference to pyrrolizidine alkaloids. Vet. Hum. Toxicol. 36 (1994) 240-247
5. Cheeke P.R. Natural toxicants in feeds, forages, and poisonous plants. second ed. (1998), Interstate, Danville, Illinois pp. 338-352
6. Copple B.L., Banes A., Ganey P.E., and Roth R.A. Endothelial cell injury and fibrin deposition in rat liver after monocrotaline exposure. Toxicol. Sci. 65 (2002) 309-318
7. Culvenor C.C.J., Jago M.V., Peterson J.E., Smith L.W., Payne A.L., Campbell D.G., Edgar J.A., and Frahn J.L. Toxicity of Echium plantagineum (Paterson's curse). I. Marginal toxic effects in Merino wethers from long-term feeding. Aust. J. Agric. Res. 35 (1984) 293-304
8. Dantas A.F.M., Nobre V.M.T., Riet-Correa F., Tabosa I.M., Júnior G.S., Medeiros J.M., Silva R.M.N., Silva E.M.N., Anjos B.L., and Medeiros J.K.D. Intoxicação crônica espontânea por Crotalaria retusa (Fabaceae) em ovinos na região do semi-árido paraibano. Brasil. Pesq. Vet. Bras. 24 Suppl. (2004) 18-19
9. Duringer J.M.M., Buhler D.R., and Craig A.M. Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle. Am. J. Vet. Res. 65 (2005) 1563-1572
10. Hanumegowda U.M., Copple B.L., Shibuya M., Malle M., Ganey P.E., and Roth R.A. Basement membrane and matrix metalloproteinases in monocrotaline-induced liver injury. Toxicol. Sci. 76 (2003) 237-246
11. Hooper P.T. Pyrrolizidine alkaloid poisoning - pathology with particular reference to differences in animal and plant species. In: Keeler R., Van Kampen K.R., and James L.F. (Eds). Effects of Poisonous Plants on Livestock (1978), Academic Press, New York 161-176
12. Huan J., Miranda C.L., Buhler D.R., and Cheeke P.R. Species differences in the hepatic microsomal enzyme metabolim of the pyrrolizidine alkaloids. Toxicol. Lett. 99 (1998) 127-137
13. Ilha M.R.S., Loretti A.P., Barros S.S., and Barros C.S.L. Intoxicação espontânea por Senecio brasiliensis (Asteraceae) em ovinos no Rio Grande do Sul. Pesq. Vet. Bras. 21 (2001) 123-138
14. Kellerman T.S., Coetzer J.A.W., Naudé T.W., and Botha C.J. Plant Poisonings and Mycotoxicoses of Livestock in Southern Africa (2005), Oxford University Press, Cape Town 310p
15. Kelly W.R. The liver and biliary system. In: Jubb K.V.F., Kennedy P.C., and Palmer N. (Eds). Pathology of domestic animals. fourth ed. vol. 2 (1993), Academic Press, San Diego 319-406 chapter 2
16. Kumari S., Kapur K.K., and Atal C.K. Occurrence of a high monocrotaline yielding strain of Crotalaria retusa. Curr. Sci. 35 (1966) 546-547
17. Lanigan G.W. Metabolism of pyrrolizidine alkaloids in the ovine rumen. II. Some factors affecting rate of alkaloid breakdown by rumen fluid in vitro. Aust. J. Agric. Res. 21 (1970) 633-639
18. Lanigan G.W. Peptococcus heliotrinreducans, sp. nov., a cytochrome-producing anaerobe which metabolizes pyrrolizidine alkaloids. J. Gen. Microbiol. 94 (1976) 1-10
19. Mattocks A.R. Chemistry and Toxicology of Pyrrolizidine Alkaloids (1986), Academic Press, Orlando 393p
20. Nobre V.M.T., Riet-Correa F., Dantas A.F.M., Tabosa I.M., Medeiros R.M.T., and Barbosa Filho J.M. Intoxication by Crotalaria retusa in ruminants and Eqüidae in the state of Paraíba, northeastern Brazil. In: Acamovich T., Stewart C.S., and Pennycott T.W. (Eds). Plant Poisoning and Related Toxins (2004), CAB International, Glasgow 275-279
21. Nobre V.M.T., Riet-Correa F., Barbosa Filho J.M., Tabosa I.M., and Vasconcelos J.S. Intoxicação por Crotalaria retusa (Fabaceae) em eqüídeos no semi-árido da Paraíba. Pesq. Vet. Bras. 24 (2004) 132-143
22. Nobre V.M.T., Dantas A.F.M., Riet-Correa F., Barbosa Filho J.M., Tabosa I.M., and Vasconcelos J.S.V. Acute intoxication by Crotalaria retusa in sheep. Toxicon 45 (2005) 347-352
23. Pereira T.N., Webb R.I., Reilly P.E., Seawright A.A., and Prakash A.S. Dehydromonocrotaline generates sequence-selective N-7 guanine alkylation and heat and alkali stable multiple fragment DNA crosslinks. Nucleic Acids Res. 26 (1998) 5441-5447
24. Pilbeam D.J., Lyon-Joyce A.J., and Bell E.A. Occurrence of pyrrolizidine alkaloid monocrotaline in Crotalaria seeds. J. Nat. Prod. 46 (1983) 601-605
25. Riet-Correa F., Tabosa I.M., Azevedo E.O., Medeiros R.M.T., Simões S.V.D., Dantas A.A., Alves J.C., Nobre V.M.T., Athaylde A.C., Gomes A.A., and Lima E.F. Doenças de ruminantes e eqüinos no semi-árido da Paraíba. Semi-Árido em Foco, Patos 1 (2003) 2-86
26. Schmid M., and von Forstner M. Laboratory testing in veterinary medicine. Diagnosis and clinical monitoring (1986), Boehringer Mannheim, Manheim, Germany 77-92
27. Seaman J.T. Pyrrolizidine alkaloid poisoning of sheep in New South Wales. Aust. Vet. J. 64 (1987) 164-167
28. St George-Grambauer T.D. Hepatogenous chronic copper poisoning in sheep in south Australia due the consumption of Echium plantagineum L. (Salvation Jane). Aust. Vet. J. 34 (1962) 288-293
29. Swick R.A., Miranda C.L., Cheeke P.R., and Buhler D.R. Effect of phenobarbital on toxicity of pyrrolizidine (Senecio) alkaloids in sheep. J. Anim. Sci. 56 (1983) 887-894
30. Williams M.C., and Molyneux R.J. Occurrence, concentration and toxicity of pyrrolizidine alkaloids in Crotalaria seeds. Weed Sci. 35 (1987) 476-481