Species differences in the hepatic microsomal enzyme metabolism of the pyrrolizidine alkaloids

Toxicology Letters

Volumn 99, Issue 2, 1998, Pages 127-137

  Huan, Jian Ya ^a   Miranda, Cristobal L ^a   Buhler, Donald R ^a   Cheeke, Peter R ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Cytochrome P450s; Flavin containing monooxygenases; Glutathione conjugation; Pyrrolizidine alkaloids; Species

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; PYRROLIZIDINE ALKALOID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATTLE; CHICKEN; CONJUGATION; CONTROLLED STUDY; DETOXIFICATION; GERBIL; GUINEA PIG; HAMSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME METABOLISM; NONHUMAN; PRIORITY JOURNAL; QUAIL; RABBIT; RAT; SHEEP; SPECIES DIFFERENCE; TOXICOKINETICS;

ANIMALS; ANIMALS, DOMESTIC; CATTLE; CHICKENS; COTURNIX; CRICETINAE; CYTOCHROME P-450 ENZYME SYSTEM; GERBILLINAE; GLUTATHIONE; MESOCRICETUS; METABOLIC DETOXICATION, DRUG; MICROSOMES, LIVER; MONOCROTALINE; OXYGENASES; PYRROLIZIDINE ALKALOIDS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

ANIMALIA; BOS TAURUS; CRICETINAE; GALLUS GALLUS; GERBILLINAE; ORYCTOLAGUS CUNICULUS; OVIS ARIES; PHASIANIDAE;

EID: 0032444587     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00152-0     Document Type: Article

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