-
1
-
-
0032030770
-
Histone acetylation and transcriptional regulation mechanisms
-
Struhl K: Histone acetylation and transcriptional regulation mechanisms. Genes Dev 12: 599-606, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 599-606
-
-
Struhl, K.1
-
2
-
-
0034045040
-
Histone deacetylases, transcriptional control, and cancer
-
Cress WD and Seto E: Histone deacetylases, transcriptional control, and cancer. J Cell Physiol 184: 1-16, 2000.
-
(2000)
J Cell Physiol
, vol.184
, pp. 1-16
-
-
Cress, W.D.1
Seto, E.2
-
3
-
-
0035755974
-
Histone deacetylases and cancer: Causes and therapies
-
Marks P, Rifkind RA, Richon VM, Breslow B, Miller T and Kelly WK: Histone deacetylases and cancer: causes and therapies. Nat Rev Cancer 1: 194-202, 2001.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
Breslow, B.4
Miller, T.5
Kelly, W.K.6
-
4
-
-
34547864236
-
Histone deacetylase inhibitors: Molecular mechanisms of action
-
Xu WS, Parmigiani RB and Marks PA: Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene 26: 5541-5552, 2007.
-
(2007)
Oncogene
, vol.26
, pp. 5541-5552
-
-
Xu, W.S.1
Parmigiani, R.B.2
Marks, P.A.3
-
5
-
-
0026548820
-
Morphological reversion of sis-transformed NIH3T3 cells by trichostatin A
-
Sugita K, Koizumi K and Yoshida H: Morphological reversion of sis-transformed NIH3T3 cells by trichostatin A. Cancer Res 52: 168-172, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 168-172
-
-
Sugita, K.1
Koizumi, K.2
Yoshida, H.3
-
6
-
-
0034665124
-
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo
-
Butler LM, Agus DB, Scher HI, Higgins B, Rose A, Cordon-Cardo C, Thaler HT, Rifkind RA, Marks PA and Richon VM: Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo. Cancer Res 60: 5165-5170, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 5165-5170
-
-
Butler, L.M.1
Agus, D.B.2
Scher, H.I.3
Higgins, B.4
Rose, A.5
Cordon-Cardo, C.6
Thaler, H.T.7
Rifkind, R.A.8
Marks, P.A.9
Richon, V.M.10
-
7
-
-
4644304383
-
Histone deacetylase inhibitors specifically nonproliferating tumor cells
-
Burgess A, Ruefli A, Beamish H, Warrener R, Saunders N, Johnstone R and Gabrielli B: Histone deacetylase inhibitors specifically nonproliferating tumor cells. Oncogene 23: 6693-6701, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 6693-6701
-
-
Burgess, A.1
Ruefli, A.2
Beamish, H.3
Warrener, R.4
Saunders, N.5
Johnstone, R.6
Gabrielli, B.7
-
8
-
-
4444239987
-
The histone deacetylase inhibitor suberic bishhydroxamate regulates the expression of multiple apoptotic mediators of melanoma cells
-
Zhang XD, Gillespie SK, Borrow JM and Hersey P: The histone deacetylase inhibitor suberic bishhydroxamate regulates the expression of multiple apoptotic mediators of melanoma cells. Mol Cancer Ther 3: 425-435, 2004.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 425-435
-
-
Zhang, X.D.1
Gillespie, S.K.2
Borrow, J.M.3
Hersey, P.4
-
9
-
-
33750288048
-
Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor
-
Xu W, Ngo L, Perez G, Dokmanovic M and Marks PA: Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor. Proc Natl Acad Sci USA 103: 15540-15545, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15540-15545
-
-
Xu, W.1
Ngo, L.2
Perez, G.3
Dokmanovic, M.4
Marks, P.A.5
-
10
-
-
34250200750
-
Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine
-
Donadelli M, Costanzo C, Beghelli S, Scupoli T, Dandrea M, Bonora A, Piacentini P, Budillon A, Caraglia M, Scarpa A and Palmieri M: Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine. Biochim Biophys Acta 1773: 1095-1106, 2007.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1095-1106
-
-
Donadelli, M.1
Costanzo, C.2
Beghelli, S.3
Scupoli, T.4
Dandrea, M.5
Bonora, A.6
Piacentini, P.7
Budillon, A.8
Caraglia, M.9
Scarpa, A.10
Palmieri, M.11
-
11
-
-
3042618526
-
Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors
-
Zhang Y, Jung M and Dritschilo A: Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors. Radiat Res 161: 667-674, 2004.
-
(2004)
Radiat Res
, vol.161
, pp. 667-674
-
-
Zhang, Y.1
Jung, M.2
Dritschilo, A.3
-
12
-
-
1642576220
-
Enhanced radiation-induced cell killing and prolongation of γH2AX foci expression by the histone deacetyylase inhibitor MS-275
-
Camphausen K, Burgan W, Cerra M, Oswald KA, Trepel JB, Lee MJ and Tofilon PJ: Enhanced radiation-induced cell killing and prolongation of γH2AX foci expression by the histone deacetyylase inhibitor MS-275. Cancer Res 64: 316-321, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 316-321
-
-
Camphausen, K.1
Burgan, W.2
Cerra, M.3
Oswald, K.A.4
Trepel, J.B.5
Lee, M.J.6
Tofilon, P.J.7
-
13
-
-
0022366477
-
Enhancement of radiation injury in human colon tumor cells by the maturational agent sodium butyrate (NaB)
-
Arundel GM, Glicksman AS and Leith JT: Enhancement of radiation injury in human colon tumor cells by the maturational agent sodium butyrate (NaB). Radiat Res 104: 443-448, 1985.
-
(1985)
Radiat Res
, vol.104
, pp. 443-448
-
-
Arundel, G.M.1
Glicksman, A.S.2
Leith, J.T.3
-
14
-
-
27644586649
-
Histone deacetylase inhibitors radiosensitizes human melanoma cells by suppressing DNA repair activity
-
Munshi A, Kurland JF, Nishikawa T, Tanaka T, Hobbs ML, Tucker SL, Ismail S, Stevens C and Meyn RE: Histone deacetylase inhibitors radiosensitizes human melanoma cells by suppressing DNA repair activity. Clin Cancer Res 11: 4912-4922, 2005.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4912-4922
-
-
Munshi, A.1
Kurland, J.F.2
Nishikawa, T.3
Tanaka, T.4
Hobbs, M.L.5
Tucker, S.L.6
Ismail, S.7
Stevens, C.8
Meyn, R.E.9
-
15
-
-
33748360764
-
Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of γ-H2AX foci
-
Munshi A, Tanaka T, Hobbs ML, Tucker SL, Richon VM and Meyn RE: Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of γ-H2AX foci. Mol Cancer Ther 5: 1967-1974, 2006.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1967-1974
-
-
Munshi, A.1
Tanaka, T.2
Hobbs, M.L.3
Tucker, S.L.4
Richon, V.M.5
Meyn, R.E.6
-
16
-
-
36749029515
-
Radiosensitization by the histone deacetylase inhibitor PCI-24781
-
Banuelos CA, Banáth JP, MacPhail SH, Zhao J, Reitsema T and Olive PL: Radiosensitization by the histone deacetylase inhibitor PCI-24781. Clin Cancer Res 13: 6816-6826, 2007.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6816-6826
-
-
Banuelos, C.A.1
Banáth, J.P.2
MacPhail, S.H.3
Zhao, J.4
Reitsema, T.5
Olive, P.L.6
-
17
-
-
0034124166
-
A nobel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library
-
Sun GH, Sohn TA, Ryu B and Kern SE: A nobel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library. Cancer Res 60: 3137-3142, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 3137-3142
-
-
Sun, G.H.1
Sohn, T.A.2
Ryu, B.3
Kern, S.E.4
-
18
-
-
0242330341
-
A nobel histone deadetylase inhibitor, scriptaid, enhances expression of functional estrogen α(ER) in ER negative human breast cancer cells in combination with 5-aza-2′-deoxycytidine
-
Keen JC, Yan L, Mack KM, Pettit C, Smith D, Sharma D and Davidson NE: A nobel histone deadetylase inhibitor, scriptaid, enhances expression of functional estrogen α(ER) in ER negative human breast cancer cells in combination with 5-aza-2′-deoxycytidine. Breast Cancer Res Treat 81: 177-186, 2003.
-
(2003)
Breast Cancer Res Treat
, vol.81
, pp. 177-186
-
-
Keen, J.C.1
Yan, L.2
Mack, K.M.3
Pettit, C.4
Smith, D.5
Sharma, D.6
Davidson, N.E.7
-
19
-
-
33644863529
-
A nobel deacetylase inhibitor, scriptaid, induces growth inhibition, cell cycle arrest, and apoptosis in human endometric cancer and ovarian cancer cells
-
Takai N, Ueda T, Nishida M, Nasu K and Narahara H: A nobel deacetylase inhibitor, scriptaid, induces growth inhibition, cell cycle arrest, and apoptosis in human endometric cancer and ovarian cancer cells. Int J Mol Med 17: 323-329, 2006.
-
(2006)
Int J Mol Med
, vol.17
, pp. 323-329
-
-
Takai, N.1
Ueda, T.2
Nishida, M.3
Nasu, K.4
Narahara, H.5
-
20
-
-
0742304429
-
Geldanamycin, an inhibitor of Hsp90, sensitizes human tumor cells to radiation
-
Machida H, Matsumoto Y, Shirai M and Kubota N: Geldanamycin, an inhibitor of Hsp90, sensitizes human tumor cells to radiation. Int J Radiat Biol 79: 973-980, 2003.
-
(2003)
Int J Radiat Biol
, vol.79
, pp. 973-980
-
-
Machida, H.1
Matsumoto, Y.2
Shirai, M.3
Kubota, N.4
-
21
-
-
20044390016
-
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
-
Ungerstedt JS, Sowa Y, Xu WS, Shao Y, Dokmanovic M, Perez G, Ngo L, Holmgren A, Jiang X and Marks PA: Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors. Proc Natl Acad Sci USA 102: 673-678, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 673-678
-
-
Ungerstedt, J.S.1
Sowa, Y.2
Xu, W.S.3
Shao, Y.4
Dokmanovic, M.5
Perez, G.6
Ngo, L.7
Holmgren, A.8
Jiang, X.9
Marks, P.A.10
-
22
-
-
0027395776
-
Predictive value of in vitro radiosensitivity parameters in head and neck cancers and cervical carcinoma: Preliminary correlations with local control and overall survival
-
Girinsky T, Rubin L, Pignon JP, Chavaudra N, Gazeau J, Dubray B, Cosset JM, Socie G and Fertil B: Predictive value of in vitro radiosensitivity parameters in head and neck cancers and cervical carcinoma: preliminary correlations with local control and overall survival. Int J Radiat Oncol Biol Phys 25: 3-7, 1993.
-
(1993)
Int J Radiat Oncol Biol Phys
, vol.25
, pp. 3-7
-
-
Girinsky, T.1
Rubin, L.2
Pignon, J.P.3
Chavaudra, N.4
Gazeau, J.5
Dubray, B.6
Cosset, J.M.7
Socie, G.8
Fertil, B.9
-
23
-
-
0242610850
-
Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA
-
Kim MS, Blake M, Baek JH, Kohlhagen G, Pommier Y and Carrier F: Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. Cancer Res 63: 7291-7300, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 7291-7300
-
-
Kim, M.S.1
Blake, M.2
Baek, J.H.3
Kohlhagen, G.4
Pommier, Y.5
Carrier, F.6
-
24
-
-
33845209109
-
Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells
-
Dowdy SC, Jiang S, Zhou XC, Hou X, Jin F, Podratz KC and Jiang SW: Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells. Mol Cancer Ther 5: 2767-2776, 2006.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2767-2776
-
-
Dowdy, S.C.1
Jiang, S.2
Zhou, X.C.3
Hou, X.4
Jin, F.5
Podratz, K.C.6
Jiang, S.W.7
-
25
-
-
0032489520
-
DNA double-stranded breraks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS and Bonner WM: DNA double-stranded breraks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273: 5858-5868, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
26
-
-
0034011881
-
Ku autoantigen: A multifunctional DNA binding protein
-
Tuteja R and Tuteja N: Ku autoantigen: a multifunctional DNA binding protein. Crit Rev Biochem Mol Biol 35: 1-33, 2000.
-
(2000)
Crit Rev Biochem Mol Biol
, vol.35
, pp. 1-33
-
-
Tuteja, R.1
Tuteja, N.2
-
27
-
-
0028025020
-
Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
-
Taccioli GE, Gottlieb TM, Blunt T, Priestley A, Demengeot, J, Mizuta R, Lehmann AR, Alt FW, Jackson SP and Jeggo PA: Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 265: 442-445, 1994.
-
(1994)
Science
, vol.265
, pp. 442-445
-
-
Taccioli, G.E.1
Gottlieb, T.M.2
Blunt, T.3
Priestley, A.4
Demengeot, J.5
Mizuta, R.6
Lehmann, A.R.7
Alt, F.W.8
Jackson, S.P.9
Jeggo, P.A.10
-
28
-
-
0031471226
-
Hypersensitivity of Ku80-deficient cell lien and mice to DNA damage: The effects of ionizing radiation on growth, survival, and development
-
Nussenzweig A, Sokol K, Burgman P, Li L and Li GC: Hypersensitivity of Ku80-deficient cell lien and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development. Proc Natl Acad Sci USA 94: 13588-13590, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13588-13590
-
-
Nussenzweig, A.1
Sokol, K.2
Burgman, P.3
Li, L.4
Li, G.C.5
-
29
-
-
0032998125
-
Rejoining of DNA double strand breaks in Ku80-deficient mouse fibroblasts
-
Wachsberger PR, Li WH, Guo M, Chen D, Cheong N, Ling CC, Li G and Iliakis G: Rejoining of DNA double strand breaks in Ku80-deficient mouse fibroblasts. Radiat Res 151: 398-497, 1999.
-
(1999)
Radiat Res
, vol.151
, pp. 398-497
-
-
Wachsberger, P.R.1
Li, W.H.2
Guo, M.3
Chen, D.4
Cheong, N.5
Ling, C.C.6
Li, G.7
Iliakis, G.8
-
30
-
-
0025191121
-
Synergistic effect of the v-myc omcogene with H-ras on radioresistance
-
McKenna WG, Weiss MC, Endlich B, Ling CC, Bakanauskas VJ, Kelsten ML and Muschel RJ: Synergistic effect of the v-myc omcogene with H-ras on radioresistance. Cancer Res 50: 97-107, 1990.
-
(1990)
Cancer Res
, vol.50
, pp. 97-107
-
-
McKenna, W.G.1
Weiss, M.C.2
Endlich, B.3
Ling, C.C.4
Bakanauskas, V.J.5
Kelsten, M.L.6
Muschel, R.J.7
-
31
-
-
0026708596
-
Influence of the H-ras oncogene on radiation response of a rat rhabdomyosarcoma cell line
-
Hermens AF and Bentvelzen PA: Influence of the H-ras oncogene on radiation response of a rat rhabdomyosarcoma cell line. Cancer Res 52: 3073-3082, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 3073-3082
-
-
Hermens, A.F.1
Bentvelzen, P.A.2
-
32
-
-
23044508571
-
Oncogenic H-ras up-regulates expression of Ku80 to protect cells from γ-ray irradiation in NIH3Ts cells
-
Chang IY, Youn CK, Kim HB, Kim MH, Cho HJ, Yoon Y, Lee YS, Chung MH and You HJ: Oncogenic H-ras up-regulates expression of Ku80 to protect cells from γ-ray irradiation in NIH3Ts cells. Cancer Res 65: 6811-6819, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 6811-6819
-
-
Chang, I.Y.1
Youn, C.K.2
Kim, H.B.3
Kim, M.H.4
Cho, H.J.5
Yoon, Y.6
Lee, Y.S.7
Chung, M.H.8
You, H.J.9
|