A binding question: the evolution of the receptor concept

Endeavour

Volumn 33, Issue 4, 2009, Pages 135-140

  Maehle, Andreas Holger ^a  

^a DURHAM UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG RECEPTOR;

HISTORY; HUMAN; IMMUNOLOGY; NEUROPHYSIOLOGY; SHORT SURVEY;

ALLERGY AND IMMUNOLOGY; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HUMANS; NEUROPHYSIOLOGY; RECEPTORS, DRUG;

EID: 70450280652     PISSN: 01609327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.endeavour.2009.09.001     Document Type: Short Survey

References (25)

1. De Jongh, D.K. (1964) Some Introductory Remarks on the Conception of Receptors. In Molecular Pharmacology: The Mode of Action of Biologically Active Compounds (vol. 1) (Ariëns, E.J., ed.), Academic Press, (New York), pp. xiii-xvi, on p. xvi.
2. Stille G., Bickel M.H., and Göing H. Der Weg der Arznei von der Materia Medica zur Pharmakologie: Der Weg von Arzneimittelforschung und Arzneitherapie (1994), G. Braun Fachverlage, Karlsruhe p. 390
3. Quirke V. Putting Theory into Practice: James Black, Receptor Theory and the Development of the Beta-Blockers at ICI, 1958-1978. Medical History 50 (2006) 69-92
4. Prüll C.-R., Maehle A.-H., and Halliwell R.F. A Short History of the Drug Receptor Concept (2009), Palgrave Macmillan, Basingstoke pp. 146-157
5. Maehle A.-H. Drugs on Trial: Experimental Pharmacology and Therapeutic Innovation in the Eighteenth Century (1999), Rodopi, Amsterdam pp. 223-309
6. Jones J. Medical, Philosophical and Vulgar Errors of Various Kinds Considered and Refuted (1797), T. Cadell and W. Davies, London pp. 135-136
7. Stille, Bickel, Göing (1994), pp. 383-386
8. Bynum W.F. Chemical Structure and Pharmacological Action: A Chapter in the History of 19th Century Molecular Pharmacology. Bulletin of the History of Medicine 44 (1970) 518-538
9. Parascandola J. The Controversy over Structure-Activity Relationships in the Early Twentieth Century. Pharmacy in History 16/2 (1974) 54-63
10. Silverstein A.M. Paul Ehrlich's Receptor Immunology: The Magnificent Obsession (2002), Academic Press, San Diego
11. Prüll C.-R. Part of a Scientific Master Plan? Paul Ehrlich and the Origins of his Receptor Concept. Medical History 47 (2003) 332-356
12. Ehrlich, P. (1907) Experimental Researches on Specific Therapy. In The Collected Papers of Paul Ehrlich (vol. 3) (Himmelweit, F., ed.), pp. 106-134, London, Pergamon, 1956-60
13. Maehle A.-H. "Receptive Substances": John Newport Langley (1852-1925) and his Path to a Receptor Theory of Drug Action. Medical History 48 (2004) 153-174
14. Langley J.N. On the Physiology of the Salivary Secretion. Part II. On the Mutual Antagonism of Atropin and Pilocarpin, having Especial Reference to their Relations in the Sub-Maxillary Gland of the Cat. Journal of Physiology 1 (1878) 339-369 on p. 367
15. Langley, J.N. (1905) On the Reaction of Cells and of Nerve-Endings to Certain Poisons, Chiefly as Regards the Reaction of Striated Muscle to Nicotine and to Curari. Journal of Physiology 33, pp. 374-413, on p. 399
16. Langley (1905), p. 411
17. Prüll C.-R. Caught between the Old and the New - Walther Straub (1874-1944), the Question of Drug Receptors, and the Rise of Modern Pharmacology. Bulletin of the History of Medicine 80 (2006) 465-489
18. Prüll, Maehle, Halliwell (2009), pp. 73-78, 98-99
19. Straub W. Die Bedeutung der Zellmembran für die Wirkung chemischer Stoffe auf den Organismus (1912), A. Pries, Leipzig p. 4
20. Straub, W. (1938) 'Die Frage "Ziel und Zukunft" der Pharmakologie', in Freie Vereinigung Schweiz. Physiologen (ed.), Kongressbericht III des XVI. Internationalen Physiologenkongresses 14.-19. August 1938 Zürich (Schweiz) (Basel: Birkhäuser), p. 91 (my translation)
21. Clark A.J. The Mode of Action of Drugs on Cells (1933), Edward Arnold & Co., London
22. Maehle A.-H. The Quantification and Differentiation of the Drug Receptor Theory, c. 1910-1960. Annals of Science 62 (2005) 479-500
23. Clark A.J. Discussion on the Chemical and Physical Basis of Pharmacological Action 12 November 1936. Opening Address. Proceedings of the Royal Society of London (Series B) 121 (1937) 580-584
24. Dale, H.H. (1943) Modes of Drug Action. General Discussion. General Introductory Address. Transactions of the Faraday Society 39, pp. 319-322, on p. 320
25. Ahlquist R.P. A Study of the Adrenotropic Receptors. American Journal of Physiology 153 (1948) 586-600