CrxOS maintains the self-renewal capacity of murine embryonic stem cells

Biochemical and Biophysical Research Communications

Volumn 390, Issue 4, 2009, Pages 1129-1135

  Saito, Ryota ^a,b   Yamasaki, Tokiwa ^a,b   Nagai, Yoko ^a,b   Wu, Jinzhan ^a,b   Kajiho, Hiroaki ^b   Yokoi, Tadashi ^a,c   Noda, Eiichiro ^a,c   Nishina, Sachiko ^c   Niwa, Hitoshi ^d   Azuma, Noriyuki ^c   Katada, Toshiaki ^b   Nishina, Hiroshi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^d RIKEN Center for Biosystems Dynamics Research   (Japan)

Author keywords

CrxOS; Embryonic stem cell; foxD3; Homeoprotein; In silico; Self renewal

Indexed keywords

BETA ACTIN; CRXOS PROTEIN; FOXD3 PROTEIN; HOMEODOMAIN PROTEIN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; ISOPROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; CELL STRUCTURE; COMPUTER MODEL; CONTROLLED STUDY; EMBRYONIC STEM CELL; EPISOME; GENE EXPRESSION; GENE EXPRESSION SYSTEM; GENE OVEREXPRESSION; GENE TARGETING; MOUSE; NONHUMAN; POLYOMA VIRUS; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; EMBRYONIC STEM CELLS; HOMEODOMAIN PROTEINS; MICE;

MURINAE;

EID: 70450270661     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.09.118     Document Type: Article

References (20)

1. Kitajima K., Masuhara M., Era T., Enver T., and Nakano T. GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors. EMBO J. 21 (2002) 3060-3069
2. Kanda S., Tamada Y., Yoshidome A., Hayashi I., and Nishiyama T. Over-expression of bHLH genes facilitate neural formation of mouse embryonic stem (ES) cells in vitro. Int. J. Dev. Neurosci. 22 (2004) 149-156
3. Mitsui K., Tokuzawa Y., Itoh H., Segawa K., Murakami M., Takahashi K., Maruyama M., Maeda M., and Yamanaka S. The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113 (2003) 631-642
4. Niwa H., Miyazaki J., and Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 24 (2000) 372-376
5. Alfano G., Vitiello C., Caccioppoli C., Caramico T., Carola A., Szego M.J., McInnes R.R., Auricchio A., and Banfi S. Natural antisense transcripts associated with genes involved in eye development. Hum. Mol. Genet. 14 (2005) 913-923
6. Nishina H., Fischer K.D., Radvanyi L., Shahinian A., Hakem R., Rubie E.A., Bernstein A., Mak T.W., Woodgett J.R., and Penninger J.M. Stress-signaling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3. Nature 385 (1997) 350-353
7. Camenisch G., Gruber M., Donoho G., Van Sloun P., Wenger R.H., and Gassmann M.A. Polyoma-based episomal vector efficiently expresses exogenous genes in mouse embryonic stem cells. Nucleic Acids Res. 24 (1996) 3707-3713
8. Gassmann M., Donoho G., and Berg P. Maintenance of an extrachromosomal plasmid vector in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA 92 (1995) 1292-1296
9. Annerén C., Cowan C.A., and Melton D.A. The Src family of tyrosine kinases is important for embryonic stem cell self-renewal. J. Biol. Chem. 279 (2004) 31590-31598
10. Aubert J., Dunstan H., Chambers I., and Smith A. Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation. Nat. Biotechnol. 20 (2002) 1240-1245
11. Cinquanta M., Rovescalli A.C., Kozak A.C., and Nirenberg M. Mouse Sebox homeobox gene expression in skin, brain, oocytes, and two-cell embryos. Proc. Natl. Acad. Sci. USA 97 (2000) 8904-8909
12. Takasaki N., Mclsaac R., and Dean J. Gpbox (Psx2), a homeobox gene preferentially expressed in female germ cells at the onset of sexual dimorphism in mice. Dev. Biol. 223 (2000) 181-193
13. Smits S.M., and Smidt M.P. The role of Pitx3 in survival of midbrain dopaminergic neurons. J. Neural. Transm. Suppl. 70 (2006) 57-60
14. Bulfone A., Puelles L., Porteus M.H., Frohman M.A., Martin G.R., and Rubenstein J.L. Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse longitudinal segmental boundaries. J. Neurosci. 13 (1993) 3155-3172
15. Chambers I., Colby D., Robertson M., Nichols J., Lee S., Tweedie S., and Smith A. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113 (2003) 643-655
16. Matsuda T., Nakamura T., Nakao K., Arai T., Katsuki M., Heike T., and Yokota T. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J. 18 (1999) 4261-4269
17. Stead E., White J., Faast R., Conn S., Goldstone S., Rathjen J., Dhingra U., Rathjen P., Walker D., and Dalton S. Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities. Oncogene 21 (2002) 8320-8333
18. Jirmanova L., Afanassieff M., Gobert-Gosse S., Markossian S., and Savatier P. Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells. Oncogene 21 (2002) 5515-5528
19. Hanna L.A., Foreman R.K., Tarasenko I.A., Kessler D.S., and Labosky P.A. Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes Dev. 16 (2002) 2650-2661
20. Liu Y., and Labosky P.A. Regulation of embryonic stem cell self-renewal and pluripotency by Foxd3. Stem Cells 26 (2008) 2475-2484