Increased percentage of microvessels but decreased density of larae vessels in papillary carcinomas as compared to hot and cold thyroid nodules

Experimental and Clinical Endocrinology and Diabetes

Volumn 117, Issue 10, 2009, Pages 637-644

  Sancak, S ^a   Hardt, A ^a   Ricken, A ^b   Lorenz, S ^a   Eszlinger, M ^a   Sen, L S ^c   Gulluoglu B M ^c   Sever, Z ^c   Eren, F T ^c   Akalin, N S ^c   Paschke, R ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b Institute of Anatomy   (Germany)

^c MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Autoimmunity; Cancer; Graves' disease; Multiple endocrine neoplasia; Thyroid

Indexed keywords

ACTIN ANTIBODY; ALPHA SMOOTH MUSCLE ACTIN; CD34 ANTIBODY; CD34 ANTIGEN;

ADULT; ARTICLE; BLOOD VESSEL; CLINICAL ARTICLE; COLD; COMPUTER ANALYSIS; CONTROLLED STUDY; DENSITY; DISEASE SEVERITY; ENDOCRINE OPHTHALMOPATHY; ENDOTHELIUM; GOITER; GRAVES DISEASE; HEAT; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOLOGY; MICROVASCULATURE; PRIORITY JOURNAL; PROSPECTIVE STUDY; STAINING; THYROID NODULE; THYROID PAPILLARY CARCINOMA; TISSUE SECTION; VASCULARIZATION;

ACTINS; ADENOMA; ANALYSIS OF VARIANCE; ANTIGENS, CD34; BLOOD VESSELS; CARCINOMA, PAPILLARY; GRAVES DISEASE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; NEOVASCULARIZATION, PATHOLOGIC; THYROID GLAND; THYROID NEOPLASMS;

EID: 70450267505     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0029-1202795     Document Type: Article

References (26)

1. Akslen LA, Livolsi VA. Increased angiogenesis in papillary thyroid carcinoma but lack of prognostic importance. Hum Pathol 2000; 31: 439-442 (Pubitemid 30262865)
2. Banner BF, Whitehause R, Baker SP et al. Tumor angiogenesis in stage II colorectal carcinoma: association with survival. Am J Clin Pathol 1998; 109:733-737
3. Benjamin LE, Golljanin D, Itin A et al. ESelective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 1999; 103: 159-165 (Pubitemid 29053133)
4. Cantu De León D, Frias Mendivil M, Chanona Vilchis G, Gomez C, De La Garza Salazar J. Significance of microvascular density (MVD) in cervical cancer recurrence. Int J Gynecol Cancer 2003; 13: 856-862 (Pubitemid 38235232)
5. Chan JKC, Hirokawa M, Evans H et al. Tumours of the Thyroid and Parathyroid: Follicular adenoma. In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, editors. WHO Classification of Tumours: Pathology & Genetics of Tumours of Endocrine Organs. Lyon: IARCPress; 2004; 98-103
6. Torre NG de la, Buley I, Wass JA et al. Angiogenesis and lymphangiogenesis in thyroid proliferative lesions: relationship to type and tumour behaviour. Endocr Relat Cancer 2006; 13: 931-944 (Pubitemid 44763268)
7. Dhar DK, Kubata H, Kotoh T et al. Tum, or vascularity predicts recurrence in differentiated thyroid carcinoma. Am J Surg 1998; 176: 442-447 (Pubitemid 29021544)
8. Fontanini G, Vignati S, Pacini F et al. Mic, rovessel count: an indicator of poor outcome in medullary thyroid carcinoma but not in other types of thyroid carcinoma. Mod Pathol 1996; 9: 636-641 (Pubitemid 26227564)
9. Fox SB. Quantitative angiogenesis in breast cancer. Methods Mol Med 2006; 120: 161-187
10. Fox SB, Generali DG, Harris AL. Breast tumour angiogenesis. Breast Cancer Res 2007; 9: 216-221
11. Giorgadze TA, Baloch ZW, Pasha T et al. Lymphatic and blood vessel density in the follicular patterned lesions of thyroid. Mod Pathol 2005; 18: 1424-1431 (Pubitemid 41509396)
12. Goldenberg JD, Portugal LG, Wenig BL et al. Well-differentiated thyroid carcinomas: p53 mutation status and microvessel density. Head Neck 1998; 20: 152-158
13. Herrmann G, Schumm-Draeger PM, Müller C et al. T lymphocytes, CD68-positive cells and vascularisation in thyroid carcinomas. J Cancer Res Clin Oncol 1994; 120: 651-656 (Pubitemid 24316948)
14. Martin L, Green B, Renshaw C et al. Examining the technique of angiogenesis assessment in invasive breast cancer. Br J Cancer 1997; 76: 1046-1054 (Pubitemid 27434662)
15. Parums DV, Cordell JL, Micklem K et al. JC70: a new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections. J Clin Pathol 1990; 43: 752-757 (Pubitemid 20279705)
16. Pusztaszeri MP, Seelentag W, Bosnian FT. Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand factor, and Fli-1 in normal human tissues. J Histochem Cytochem 2006; 54: 385-395
17. Sasano H, Suzuki T. Pathological evaluation of angiogenesis in human tumor. Biomed Pharmacother 2005; 59 (Suppl. 2): S334-S336
18. Segal K, Shpitzer T, Feinmesser M et al. Angiogenesis in follicular tumors of the thyroid. J Surg Oncol 1996; 63: 95-98
19. Stabenow E, Tavares MR, Ab'Saber AM et al. Angiogenesis as an indicator of metastatic potential in papillary thyroid carcinoma. Clinics 2005; 60: 233-240
20. Turner HE, Harris AL, Melmed S et al. Angiogenesis in endocrine tumors. Endocr Rev 2003; 24: 600-632
21. Turner HE, Nagy Z, Gatter KC et al. Angiogenesis in pituitary adenomas and the normal pituitary gland. J Clin Endocrinol Metab 2000; 85: 1159-1162 (Pubitemid 32269365)
22. Vermeulen PB, Gasparini G, Fox SB et al. Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. Eur J Cancer 1996; 32A: 2474-2484
23. Viacava P, Bocel G, Tonacchera M et al. Markers of cell proliferation, apoptosis, and angiogenesis in thyroid adenomas: a comparative immunohistochemical and genetic investigation of functioning and nonfunctioning nodules. Thyroid 2007; 17: 191-197 (Pubitemid 46557365)
24. Vieira SC, Zeferino LC, Da Silva BB et al. Quantification of angiogenesis in cervical cancer: a comparison among three endothelial cell markers. Gynecol Oncol 2004; 93: 121-124
25. Weidner N, Folkman J, Pozza F et al. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992; 84: 1875-1887
26. Wong NA, Willott J, Kendall MJ et al. Measurement of vascularity as a diagnostic and prognostic tool for well differentiated thyroid tumours: comparison of different methods of assessing vascularity. J Clin Pathol 1999; 52: 593-597