Microvessel count: An indicator of poor outcome in medullary thyroid carcinoma but not in other types of thyroid carcinoma

Modern Pathology

Volumn 9, Issue 6, 1996, Pages 636-641

  Fontanini, Gabriella ^a   Vignati, Silvana ^a   Pacini, Furio ^a   Pollina, Luca ^a   Basolo, Fulvio ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Angiogenesis; Cancer; Thyroid

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SURVIVAL; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; PRIORITY JOURNAL; PROGNOSIS; STATISTICAL ANALYSIS; THYROID CARCINOMA; THYROID FOLLICULAR CARCINOMA; THYROID MEDULLARY CARCINOMA; THYROID PAPILLARY CARCINOMA; TUMOR VASCULARIZATION; UNDIFFERENTIATED CARCINOMA;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CARCINOMA; CARCINOMA, MEDULLARY; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; SEX FACTORS; THYROID NEOPLASMS;

EID: 0029892557     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Folkman J, Coltran RS: Relation of vascular proliferation to tumor growth. Int Rev Exp Pathol 16:207, 1976
2. Folkman J: Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1:27, 1995
3. Weidner N: Tumor angiogenesis: Review of current applications in tumor prognostication. Sem Diagn Pathol 10:302, 1993
4. Blood CH, Zetter B: Tumor interactions with the vasculature: Angiogenesis and tumor metastasis. Biochim Biophys Acta 1032:89, 1990
5. Srivastava A, Laidler P, Davies RP, Horgan K, Hughes LE: The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. Am J Pathol 133:419, 1988
6. Vacca A, Ribatti D, Roncali L, et al.: Melanocyte tumor progression is associated with changes in angiogenesis and expression of the 67-kilodalton Lamin receptor. Cancer 72: 455, 1993
7. Weidner N, Semple JP, Welch WR, Folkman J: Tumor angiogenesis and metastasis: Correlation in invasive breast carcinoma. N Engl J Med 324:1, 1991
8. Horak ER, Leek R, Klenk N, et al.: Angiogenesis assessed by plateled/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet 2:1120, 1992
9. Gasparini G, Harris AL: Clinical importance of tumor angiogenesis in breast carcinoma: Much more than a new prognostic tool. J Clin Oncol 13:765, 1995
10. Bosari S, Lee AKC, De Lellis RA: Microvessel quantitation and prognosis in invasive breast carcinoma. Hum Pathol 23:755, 1992
11. Toi M, Kashitani J, Tominaga T: Tumor angiogenesis is an independent prognotic indicator in primary breast carcinoma. Int J Cancer 55:371, 1993
12. Gasparini G, Weidner N, Bevilacqua P, et al.: Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma. J Clin Oncol 12:454, 1994
13. Weidner N, Carroll PR, Flax J, Blumenfeld W, Folkman J: Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 143:401, 1993
14. Gasparini G, Weidner N, Maluta S, et al.: Intratumoral microvessel density and p53 protein: Correlation with metastasis in head-and-neck squamous-cell carcinoma. Int J Cancer 55:739, 1993
15. Fontanini G, Bigini D, Vignati S, et al; Microvessel count predicts metastatic disease and survival in non-small cell lung cancer. J Pathol 177:57, 1995
16. Craft PS, Harris AL: Clinical prognostic significance of tumor angiogenesis. Ann Oncol 5:305, 1994
17. Srivastava A, Laidler P, Hughes LE: Neovascularization in human cutaneous melanoma: A quantitative morphological and doppler sound study. Eur J Cancer Clin Oncol 22:1205, 1986
18. Furosato M, Wakui S, Sasaki H, Ito K, Ushigome S: Tumour angiogenesis in latent prostatic carcinoma. Br J Cancer 70: 1244, 1994
19. Macchiarini P, Fontanini G, Hardin JM, Squartini F, Angeletti CA: Relation of neovascularisation to metastasis of non-small-cell lung cancer. Lancet 2:45, 1992
20. Hay ID: Papillary thyroid carcinoma. Endocrinol Metab Clin North Am 19:545, 1990
21. Jonasson JG, Hrafnkelsson J: Nuclear DNA analysis and prognosis in carcinoma of the thyroid gland. Virchows Arch 425:349, 1994
22. Basolo F, Fugazzola L, Fontanini G, et al.: Markers of cell proliferation as prognostic factors in differentiated thyroid cancer. Int J Oncol 3:1077, 1993
23. Basolo F, Pinchera A, Fugazzola L, et al.: Expression of p21 ras protein as a prognostic factor in papillary thyroid cancer. Eur J Cancer 30:171, 1994
24. Pollina L, Pacini F, Fontanini G, et al.: Bcl-2 and p53 protein expression in thyroid carcinomas: Lack of correlation with clinico-pathological parameters and survival. Br J Cancer 73:139, 1996
25. Akslen LA, Myking AO, Salvesen H, Varhaug JE: Prognostic importance of various clinicopathological features in papillary thyroid carcinoma. Eur J Cancer 29:44, 1993
26. Mazzaferri E, Jhiang SM: Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med 97:418, 1994
27. Venkatesh YSS, Ordonez NG, Scultz PN, et al: Anaplastic carcinoma of the thyroid: a clinicopathological study of 121 cases. Cancer 66:321, 1990
28. Soares P, Cameselle-Teijero J, Sobrinho-Simoes M: Immunohistochemical detection of p53 in differentiated, poorly differentiated, and undifferentiated carcinomas of the thyroid. Histopathology 24:205, 1994
29. Dobashi Y, Sakamoto A, Sugimura H, et al.: Overexpression of p53 as a possible prognostic factor in human thyroid carcinoma. Am J Surg Pathol 17:375, 1993
30. Pacini F, Pinchera A, Mancusi F, et al.: Anaplastic thyroid carcinoma: A retrospective clinical and immunohistochemical study. Oncol Rep 1:921, 1994
31. Pacini F, Basolo F, Elisei R, et al.: Medullary thyroid cancer. Am J Clin Pathol 95:300, 1991
32. Shroder S, Bocker W, Baisch H: Prognostic factors in medullary thyroid carcinomas: Survival in relation to age, sex, stage, histology, immunohistochemistry, and DNA content. Cancer 61:806, 1988
33. Gasparini G, Pozza F, Harris AL: Evaluating the potential usefulness of new prognostic and predictive indicators in node-negative breast cancer patients. J Natl Cancer Inst 85:1206, 1993