Molecular classification of cancers of unknown primary site

Molecular Diagnosis and Therapy

Volumn 13, Issue 6, 2009, Pages 367-373

  Greco, F Anthony ^a   Erlander, Mark G ^b  

^a SARAH CANNON RESEARCH INSTITUTE   (United States)

^b BioTheranostics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR 2;

BONE METASTASIS; BREAST ADENOCARCINOMA; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER OF UNKNOWN PRIMARY SITE; CANCER THERAPY; CELL FUNCTION; CLINICAL FEATURE; COLORECTAL CANCER; CORRELATION FUNCTION; DIAGNOSTIC ACCURACY; DNA MICROARRAY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MUTATION; HUMAN; LIVER METASTASIS; LUNG METASTASIS; LUNG NON SMALL CELL CANCER; LYMPH NODE METASTASIS; METASTASIS; PANCREAS CARCINOMA; PREDICTION; PRIORITY JOURNAL; REVIEW; TREATMENT OUTCOME; TUMOR BIOPSY; VALIDATION PROCESS;

EID: 70450255207     PISSN: 11771062     EISSN: 11792000     Source Type: Journal    
DOI: 10.1007/BF03256342     Document Type: Review

References (27)

1. Greco FA, Hainsworth JD. Cancer of unknown primary site. In: DeVita Jr VT, Hellman S, Rosenberg M. editors. Cancer: principles and practice of oncology. 8th ed. Philadelphia (PA): Lippincott, 2008: 2363-2387
2. Hainsworth JD, Fizazi K. Treatment for patients with unknown primary cancer and favorable prognostic factors. Semin Oncol 2009: 36: 44-51
3. Pentheroudakis G, Golfinopoulos V, Pavlidis N. Switching benchmarks in cancer of unknown primary: from autopsy to microarray. Eur J Cancer 2007; 43: 2026-2036 (Pubitemid 47380362)
4. Oien K. Pathological evaluation of unknown primary cancer. Semin Oncol 2009; 36: 8-37
5. DeYoung BR, Wick MR. Immunohistologic evaluation of metastatic carcinomas of unknown origin: an algorithmic approach. Semin Diagn Pathol 2000; 17: 184-193
6. Al-Brahim N, Ross C., Carter B, et al. The value of postmortem examination in cases of metastasis of unknown origin-20 year retrospective data from a tertiary care center. Am Diagn Pathol 2005; 9: 77-80 (Pubitemid 40460741)
7. Bender RA, Erlander MG. Molecular classification of unknown primary cancer. Semin Oncol 2009; 36: 38-43
8. Li X, Quigg RJ, Zhou J, et al. Clinical utility of microassays: current status, existing challenges and future outlook. Curr Genomics 2008; 9: 466-474
9. Sotiriou C., Piccart MJ. Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care? Nature Rev Cancer 2007; 7: 545-553
10. Golub TR, Slonim DK, Tamayo P, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999;286:531-537
11. Ramaswamy S, Tamayo P, Rifkin R, et al. Multiclass cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci USA 2001 ; 98:15149-15154
12. 12.SuAI,WelshJB,SapinosoLM,etal. Molecularclassificationofhumancarcinomasbyuseofgeneexpressionsignatures. CancerRes2001;61:7388-7393(Pubitemid32995021)
13. 13.BloomG,YangIV,BoulwareD,etal.Multi-platform,multi-site, microarraybasedhumantumorclassification.AmerJPath2004;164:9- 16(Pubitemid38364584)
14. Tothill RW, Kowalczyk A, Rischin D, et al. An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin. Cancer Res 2005; 65: 4031-4040 (Pubitemid 40775639)
15. Talantov D, Baden J, Jatkoe T. A quantitative reverse transcriptasepolymerase chain reaction array to identify metastatic carcinoma tissue of origin. J Mol Diag 2006; 8: 320-329 (Pubitemid 44063808)
16. Rosenfeld N, Aharonov R, Meiril E, et al. MicroRNAs accurately identify cancer tissue origin. Nature Biotech 2008; 26: 462-469
17. Monzo FA, Lyons-Weiler M. Buturovic LJ, et al. Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin. J Clin Oncol 2009; 27: 2503-2508
18. Horlings HM, van Laar R, Kerst J-M, et al. Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary. J Clin Oncol 2008; 26: 4435-4441
19. Varadhachary G, Talantov D, Raber M, et al. Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation. J Clin Oncol 2008; 26: 4442-4448
20. Bridgewater J, van Laar R, Floore A, et al. Gene expression profiling may improve diagnosis in patients with carcinoma of unknown primary. Br J Cancer 2008; 98: 1425-1430 (Pubitemid 351543580)
21. Ma X-J, Pate R, Wang X, et al. Molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction array. Arch Path Lab Med 2006; 130:465-473
22. Pillai R, Deeter R, Rigl CT, et al. Validation of a microarray-based gene expression test for tumors with uncertain origins using formalin-fixed paraffin-embedded (FFPE) specimens [abstract no. e22015]. J Clin Oncol 2009; 27 (15S) [online]. Available from URL: http://meeting.ascopubs.org/ cgi/content/abstract/27/15S/e22015 [Accessed 2009 Sep 13]
23. Pentheroudakis G. Briasoulis E, Pavlidis N. Cancer of unknown primary site: missing primary or missing biology? Oncologist 2007; 12: 418-425
24. Varadhachary GR, Raber MN, Matamoros A, et al. Carcinoma of unknown primary with a colon-cancer profile-changing paradigm and emerging definitions. Lancet Oncol 2008; 9: 596-599 (Pubitemid 351722584)
25. Monzon FA, Henner WD, Medeiros F. Use of microarray-based 1550-gene expression profile-of carcinoma of unknown primary (CUP) [abstract no. 313]. Gastrointestinal Cancers Symposium, American Society of Clinical Oncology; 2009 Jan 15-17; San Francisco (CA)
26. Greco FA, Spigel DR, Yardley DA, et al. Unknown primary cancer (UPC): accuracy of tissue of origin prediction by molecular profiling [abstract no. 11070]. J Clin Oncol 2009; 27 (15S) [online]. Available from URL: http:// meeting.ascopubs.org/cgi/content/abstract/27/15S/11070 [Accessed 2009 Sep 13]
27. van Laar RK, Ma XJ, de Jong D, et al. Implementation of a novel microarraybased diagnostic test for cancer of known primary. Int J Cancer 2009; 125: 1390-1397