Expression Levels of Cyclin G2, But Not Cyclin E, Correlate With Gastric Cancer Progression1

Journal of Surgical Research

Volumn 157, Issue 2, 2009, Pages 168-174

  Choi, Min Gew ^a   Noh, Jae Hyung ^a   An, Ji Yeong ^a   Hong, Seong Kweon ^b   Park, Sung Bae ^b   Baik, Yong Hae ^c   Kim, Kyoung Mee ^a   Sohn, Tae Sung ^a   Kim, Sung ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Kangwon National University   (South Korea)

^c Dongguk University College of Medicine   (South Korea)

Author keywords

cyclin E; cyclin G2; gastric cancer; immunohistochemistry

Indexed keywords

CYCLIN E; CYCLIN G2; CYCLINE; UNCLASSIFIED DRUG;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER GROWTH; CANCER INVASION; CANCER STAGING; DISTANT METASTASIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INCIDENCE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; STOMACH CANCER; TISSUE MICROARRAY;

ADENOCARCINOMA; ADENOCARCINOMA, MUCINOUS; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SIGNET RING CELL; CYCLIN E; CYCLIN G2; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM STAGING; PROGNOSIS; RETROSPECTIVE STUDIES; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 70450238064     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.06.020     Document Type: Article

References (21)

1. Hartwell L.H., and Kastan M.B. Cell cycle control and cancer. Science 266 (1994) 1821
2. Kastan M.B., and Bartek J. Cell-cycle checkpoints and cancer. Nature 432 (2004) 316
3. Michalides R. Cell cycle regulators: role in etiology, prognosis and treatment in cancer. Ann Oncol 13 (2002) 39 Suppl 4
4. Grana X., and Reddy E.P. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene 11 (1995) 211
5. Ito Y, Yoshida H, Uruno T, et al. Decreased expression of cyclin G2 is significantly linked to the malignant transformation of papillary carcinoma of the thyroid. Anticancer Res 2003;23:2335.
6. Frasor J, Danes JM, Komm B, et al. Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 2003;144:4562.
7. Kim Y., Shintani S., Kohno Y., et al. Cyclin G2 dysregulation in human oral cancer. Cancer Res 64 (2004) 8980
8. AJCC Cancer Staging Manual, 6th Edition. New York: Springer, 2002.
9. Horne M.C., Goolsby G.L., Donaldson K.L., et al. Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression. J Biol Chem 271 (1996) 6050
10. Akama Y., Yasui W., Yokozaki H., et al. Frequent amplification of the cyclin E gene in human gastric carcinomas. Jpn J Cancer Res 86 (1995) 617
11. Sakaguchi T., Watanabe A., Sawada H., et al. Prognostic value of cyclin E and p53 expression in gastric carcinoma. Cancer 82 (1998) 1238
12. Muller W., Noguchi T., Wirtz H.C., et al. Expression of cell-cycle regulatory proteins cyclin D1, cyclin E, and their inhibitor p21 WAF1/CIP1 in gastric cancer. J Pathol 189 (1999) 186
13. Takano Y., Kato Y., van Diest P.J., et al. Cyclin D2 overexpression and lack of p27 correlate positively and cyclin E inversely with a poor prognosis in gastric cancer cases. Am J Pathol 156 (2000) 585
14. Xiangming C., Natsugoe S., Takao S., et al. The cooperative role of p27 with cyclin E in the prognosis of advanced gastric carcinoma. Cancer 89 (2000) 1214
15. Chetty R., and Sitti C.W. Cyclin E immunoexpression in gastric cancer does not correlate with clinicopathological parameters. Histopathology 42 (2003) 66
16. Bani-Hani K.E., Almasri N.M., Khader Y.S., et al. Combined evaluation of expressions of cyclin E and p53 proteins as prognostic factors for patients with gastric cancer. Clin Cancer Res 11 (2005) 1447
17. Tamura K., Kanaoka Y., Jinno S., et al. Cyclin G: A new mammalian cyclin with homology to fission yeast Cig1. Oncogene 8 (1993) 2113
18. Okamoto K., and Beach D. Cyclin G is a transcriptional target of the p53 tumor suppressor protein. EMBO J 13 (1994) 4816
19. Zauberman A., Lupo A., and Oren M. Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites. Oncogene 10 (1995) 2361
20. Bates S., Rowan S., and Vousden K.H. Characterisation of human cyclin G1 and G2: DNA damage inducible genes. Oncogene 13 (1996) 1103
21. Liu J., Cui Z.S., Luo Y., et al. Effect of cyclin G2 on proliferative ability of SGC-7901 cell. World J Gastroenterol 10 (2004) 1357