Montelukast Protects Axial Pattern Rat Skin Flaps Against Ischemia/Reperfusion Injury

Journal of Surgical Research

Volumn 157, Issue 2, 2009, Pages 181-186

  Gideroglu, Kaan ^a   Yilmaz, Fahrettin ^a   Aksoy, Fadullah ^b   Bugdayci, Guler ^a   Saglam, Ibrahim ^a   Yimaz, Fahri ^a  

^a ABANT IZZET BAYSAL UNIVERSITY   (Turkey)

^b HASEKI EDUCATION AND RESEARCH HOSPITAL   (Turkey)

Author keywords

axial pattern skin flap; ischemia reperfusion injury; montelukast

Indexed keywords

ANTIOXIDANT; GLUTATHIONE; MALONALDEHYDE; MONTELUKAST; MYELOPEROXIDASE; OXIDIZING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SELECTIVITY; ENZYME ACTIVITY; GRAFT SURVIVAL; HISTOLOGY; ISCHEMIA; MALE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SKIN ISLAND FLAP; SURVIVAL RATE;

ACETATES; ANIMALS; CELL MOVEMENT; GLUTATHIONE; GRAFT SURVIVAL; INJECTIONS, INTRAPERITONEAL; LEUKOTRIENE ANTAGONISTS; MALE; MALONDIALDEHYDE; MODELS, ANIMAL; NEUTROPHILS; PEROXIDASE; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SKIN TRANSPLANTATION; SURGICAL FLAPS; TREATMENT OUTCOME;

EID: 70450238022     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.07.031     Document Type: Article

References (31)

1. Sagi A., Ferder M., Levens D., et al. Improved survival of island flaps after prolonged ischemia by perfusion with superoxide dismutase. Plast Reconstr Surg 77 (1986) 639
2. Hofeling A.D., Bello G., Jackson I., et al. Hemoglobin based oxygen carrier does not improve survival of ischemic rat island groin flaps. J Invest Surg 19 (2006) 299
3. Ayhan S., Tugay C., Norton S., et al. Dehydroepiandrosterone protects the microcirculation of muscle flaps from ischemia-reperfusion injury by reducing the expression of adhesion molecules. Plast Reconstr Surg 11 (2003) 2286
4. Aydogan H., Gurlek A., Parlakpinar H., et al. Beneficial effects of caffeic acid phenethyl ester (CAPE) on the ischemia-reperfusion injury in rat skin flaps. J Plast Reconstr Aesthet Surg 60 (2007) 563
5. Ichikaea F., and Miyazaki S. New biodefence strategies by neutrophils. Arch Immunol Ther Exp 53 (2005) 226
6. Kelly K.J., Williams W.W., Colvin R.B., et al. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest 97 (1996) 1056
7. Sener G., Sehirli O., Velioglu-Ogunç A., et al. Montelukast protects against renal ischemia-reperfusion in jury in rats. Pharmacol Res 54 (2006) 65
8. Cetin C., Köse A.A., Aral E., et al. Protective effect of fucoidin (a neutrophil rolling inhibitor) on Ischemia reperfusion injury: Experimental study in rat epigastric island flaps. Ann Plast Surg 47 (2001) 540
9. Yücel A., Senyuva C., Andican G., et al. Secondary venous ischemic injury associated with neutrophil infiltration and lipid peroxidation: Amelioration of injury by cyclosporin A in a rat inguinal island flap. Ann Plast Surg 45 (2000) 54
10. Wenzel S.E. Arachidonic acid metabolites: Mediators of inflammation in asthma. Pharmacotherapy 1 (1997) 3
11. Sener G., Kabasakal L., Cetinel S., et al. Leukotriene receptor blocker montelukast protects against burn-induced oxidative injury of the skin and remote organs. Burns 31 (2005) 587
12. Petry J.J., and Wortham K.A. The anatomy of the epigastric flap in the experimental rat. Plast Reconstr. Surg 74 (1984) 410
13. Kuo Y.R., Jeng S., Wang F., et al. Platelet glyci{dotless}oprotein IIb/IIIa receptor antagonist (abciximab) inhibited platelet activation and promoted skin flap survival after ischemia/reperfusion injury. J Surg Res 107 (2002) 50
14. Ueda K., Nozawa M., Miyasaka M., et al. Sulfatide protects skin flaps against ischemia-reperfusion injury. J Surg Res 80 (1998) 200
15. Esterbauer H., and Cheeseman K.H. In: Packer C., and Glazer AN. (Eds). Oxygen radicals in biological systems, methods in enzymology. Determination of aldehydic lipid peroxidation products. Malonaldehyde and 4-hydroxynonenal Vol 186 (1990), Academic Press, California 407-421
16. Beutler E. Red cell metabolism. A Manual of Biochemical Methods (1984), Grune & Stratton, Orlando 131-134
17. Bradley P.P., Priebat D.A., Christensen R.D., et al. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78 (1982) 206
18. Lowry O., Rosenbraugh N., Farr L., et al. Protein measurement with the Folin-phenol reagent. J Biol Chem 183 (1951) 265
19. Bilen B.T., Kilinç H., Alaybeyoglu N., et al. Effect of caffeic acid phenethyl ester on survival of axial pattern flaps in rats with ischemia-reperfusion injuries. Scand J Plast Reconstr Surg Hand Surg 40 (2006) 78
20. Aust S.D., Thomas C.E., Morehouse L.A., et al. Active oxygen and toxicity. Adv Exp Med Biol 197 (1986) 513
21. Kiang J.G., and Tsen K.T. Biology of hypoxia. Chin J Physiol 49 (2006) 223
22. Takamatsu Y., Shimada K., Chijiiwa K., et al. Role of leukotriens on hepatic ischemia reperfusion injury in rats. J Surg Res 119 (2004) 14
23. Baba T., Black K.L., Ikezaki K., et al. Intracarotid infusion of leukotriene C4 selectively increases blood-brain barrier permeability after focal ischemia in rats. J Cereb Blood Flow Metab 11 (1991) 638
24. Yu G.L., Wei E.Q., Zhang S.H., et al. Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice. Pharmacology 73 (2005) 31
25. Zhang S.H., Wei E.Q., Zhu C.Y., et al. Protective effect of ONO 1078, a leukotriene receptor antagonist, on focal cerebral ischemia induced by endothelin-1 rats. Acta Pharm Sin 39 (2004) 1
26. Katoh T., Lianos E.A., Fukanaga M., et al. Leukotriene D4 is a mediator of proteinuria of glomerular hemodynamic abnormalities in passive Heymann nephritis. J Clin Invest 91 (1993) 1507
27. Siemenow M., and Arslan E. Ischemia reperfusion injury: A review relation to free tissue transfers. Microsurgery 24 (2004) 468
28. Zhang F., Hu E.C., Gerzenshtein J., et al. The expression of proinflammatory cytokines in the rat muscle flap with ischemia reperfusion injury. Ann Plast Surg 54 (2005) 313
29. Cetinkale O., Bilgic L., Bolayirli M., et al. Involvement of neutrophils in ischemia- reperfusion injury of inguinal island skin flaps in rats. Plast Recons Surg 102 (1998) 153
30. Parlakpi{dotless}nar H., Sahna E., Mk O., et al. Physiological and pharmacological concentrations of melatonin protects against cisplatin induced acute renal injury. J Pineal Res 33 (2002) 161
31. Gurlek A., Celik M., Parlakpinar H., et al. The protective effect of melatonin on ischemia reperfusion injury in the groin (inferior epigastric) flap model in rats. J Pineal Res 40 (2006) 312