A mycobacterial cyclic AMP phosphodiesterase that moonlights as a modifier of cell wall permeability

Journal of Biological Chemistry

Volumn 284, Issue 47, 2009, Pages 32846-32857

  Podobnik, Marjetka ^a   Tyagi, Richa ^b   Matange, Nishad ^b   Dermol, Urška ^a   Gupta, Arun K ^c   Mattoo, Rohini ^b   Seshadri, Kothandaraman ^c   Visweswariah, Sandhya S ^b  

^a NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CRYSTAL STRUCTURE; ESTERS; MAMMALS;

C-TERMINAL REGIONS; CATALYTIC DOMAINS; CYTOTOXIC COMPOUNDS; METALLOPHOSPHOESTERASE; MULTIPLE SUBSTRATES; MYCOBACTERIUM TUBERCULOSIS; PATHOGENIC MYCOBACTERIA; PHOSPHODIESTERASES;

CYTOLOGY;

CYCLIC AMP PHOSPHODIESTERASE; METALLOPHOSPHOESTERASE; PHOSPHATASE; PROTEIN RV0805; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; ENZYME ACTIVE SITE; ENZYME LOCALIZATION; ENZYME SUBSTRATE; GENE MUTATION; GENE OVEREXPRESSION; HYDROPHOBICITY; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; WILD TYPE;

BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MAMMALIA; MYCOBACTERIUM TUBERCULOSIS;

EID: 70450237641     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.049635     Document Type: Article

References (34)

1. Ehrt, S., and Schnappinger, D. (2009) Cell. Microbiol. 11, 1170-1178
2. Shenoy, A. R., and Visweswariah, S. S. (2006) FEBS Lett. 580, 3344-3352
3. Shenoy, A. R., and Visweswariah, S. S. (2006) Trends Microbiol. 14, 543-550
4. Agarwal, N., Lamichhane, G., Gupta, R., Nolan, S., and Bishai, W. R. (2009) Nature 460, 98-102
5. Conti, M., and Beavo, J. (2007) Annu. Rev. Biochem. 76, 481-511
6. Shenoy, A. R., Sreenath, N., Podobnik, M., Kovacevic, M., and Visweswariah, S. S. (2005) Biochemistry 44, 15695-15704
7. Hopfner, K. P., Karcher, A., Craig, L., Woo, T. T., Carney, J. P., and Tainer, J. A. (2001) Cell 105, 473-485
8. Voegtli, W. C., White, D. J., Reiter, N. J., Rusnak, F., and Rosenzweig, A. C. (2000) Biochemistry 39, 15365-15374
9. Keppetipola, N., and Shuman, S. (2008) J. Biol. Chem. 283, 30942-30949
10. Richter, W. (2002) Proteins 46, 278-286
11. Jackson, C. J., Carr, P. D., Liu, J. W., Watt, S. J., Beck, J. L., and Ollis, D. L. (2007) J. Mol. Biol. 367, 1047-1062
12. Hierro, A., Rojas, A. L., Rojas, R., Murthy, N., Effantin, G., Kajava, A. V., Steven, A. C., Bonifacino, J. S., and Hurley, J. H. (2007) Nature 449, 1063-1067
13. Collins, B. M., Skinner, C. F., Watson, P. J., Seaman, M. N., and Owen, D. J. (2005) Nat. Struct. Mol. Biol. 12, 594-602
14. Shenoy, A. R., Capuder, M., Draskovic, P., Lamba, D., Visweswariah, S. S., and Podobnik, M. (2007) J. Mol. Biol. 365, 211-225
15. Tyagi, R., Shenoy, A. R., and Visweswariah, S. S. (2009) J. Biol. Chem. 284, 5217-5228
16. Shenoy, A. R., and Visweswariah, S. S. (2003) Anal. Biochem. 319, 335-336
17. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
18. Collaborative Computational Project, Number 4 (1994) Acta Crystallogr. D Biol. Crystallogr. 50, 760-763
19. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119
20. DeLano, W. L. (2002) The PyMOL Molecular Graphics System, DeLano Scientific LLC, Palo Alto, CA
21. Weininger, D. (1988) J. Chem. Inf. Comput. Sci. 28, 31-36
22. Delogu, G., Bua, A., Pusceddu, C., Parra, M., Fadda, G., Brennan, M. J., and Zanetti, S. (2004) FEMS Microbiol. Lett. 239, 33-39
23. Dass, B. K., Sharma, R., Shenoy, A. R., Mattoo, R., and Visweswariah, S. S. (2008) J. Bacteriol. 190, 3824-3834
24. Rezwan, M., Lanéelle, M. A., Sander, P., and Daffé, M. (2007) J. Microbiol. Methods 68, 32-39
25. Zor, T., and Selinger, Z. (1996) Anal. Biochem. 236, 302-308
26. Shenoy, A. R., Sreenath, N. P., Mahalingam, M., and Visweswariah, S. S. (2005) Biochem. J. 387, 541-551
27. Ding, F., Prutzman, K. C., Campbell, S. L., and Dokholyan, N. V. (2006) Structure 14, 5-14
28. Liu, J., and Nikaido, H. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 4011-4016
29. Kana, B. D., Gordhan, B. G., Downing, K. J., Sung, N., Vostroktunova, G., Machowski, E. E., Tsenova, L., Young, M., Kaprelyants, A., Kaplan, G., and Mizrahi, V. (2008) Mol. Microbiol. 67, 672-684
30. Hadler, K. S., Tanifum, E. A., Yip, S. H., Mitic, N., Guddat, L. W., Jackson, C. J., Gahan, L. R., Nguyen, K., Carr, P. D., Ollis, D. L., Hengge, A. C., Larrabee, J. A., and Schenk, G. (2008) J. Am. Chem. Soc. 130, 14129-14138
31. Krissinel, E., and Henrick, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2256-2268
32. Williams, R. S., Moncalian, G., Williams, J. S., Yamada, Y., Limbo, O., Shin, D. S., Groocock, L. M., Cahill, D., Hitomi, C., Guenther, G., Moiani, D., Carney, J. P., Russell, P., and Tainer, J. A. (2008) Cell 135, 97-109
33. Boyne, M. E., Sullivan, T. J., amEnde, C. W., Lu, H., Gruppo, V., Heaslip, D., Amin, A. G., Chatterjee, D., Lenaerts, A., Tonge, P. J., and Slayden, R. A. (2007) Antimicrob. Agents Chemother. 51, 3562-3567
34. Vandal, O. H., Pierini, L. M., Schnappinger, D., Nathan, C. F., and Ehrt, S. (2008) Nat. Med. 14, 849-854