A new sample preparation method for determination of acidic drugs in sewage sludge applying microwave assisted solvent extraction followed by gas chromatography-mass spectrometry

Microchemical Journal

Volumn 94, Issue 1, 2010, Pages 36-41

  Dobor, József ^a   Varga, Margit ^a   Yao, Jun ^b   Chen, Huilun ^b   Palkó, György ^c   Záray, Gyula ^a  

^a EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^b CHINA UNIVERSITY OF GEOSCIENCES   (China)

^c Budapest Sewage Works Ltd   (Hungary)

Author keywords

Acidic pharmaceuticals; Dispersive matrix extraction; Gas chromatography; Microwave assisted solvent extraction; Sewage sludge; Solid phase extraction

Indexed keywords

EID: 70450223139     PISSN: 0026265X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.microc.2009.08.007     Document Type: Article

References (41)

1. Kümmerer K. Drugs in the environment: emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources - review. Chemosphere 45 (2001) 957-969
2. Heberer T. Occurrence, fate and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicol. Lett. 131 (2002) 5-17
3. Heberer T. Tracking persistent pharmaceutical residues from municipal sewage to drinking water. J. Hydrol. 266 (2002) 175-189
4. Koutsouba V., Heberer T., Fuhrmann B., Schmidt-Baumler K., Tsipi D., and Hiskia A. Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry. Chemosphere 51 (2003) 69-75
5. Jones O.A.H., Voulvoulis N., and Lester J.N. The occurrence and removal of selected pharmaceutical compounds in a sewage treatment works utilising activated sludge treatment. Environ. Pollut. 145 (2007) 738-744
6. Öllers S., Singer H.P., Fassler P., and Müller S.R. Simultaneous quantification of neutral and acidic pharmaceuticals and pesticides at the low-ng/l level in surface and waste water. J Chromatogr A 911 (2001) 225-234
7. Sacher F., Lange F.T., Brauch H.-J., and Blankenhorn I. Pharmaceuticals in groundwaters. Analytical methods and results of a monitoring program in Baden-Württemberg, Germany. J. Chromatogr. A 938 (2001) 199-210
8. Hernando M.D., Heath E., Petrovic, and Barceló D. Trace-level determination of pharmaceutical residues by LC-MS/MS in natural and treated waters. A pilot-survey study. Anal. Bioanal. Chem. 385 (2006) 985-991
9. Ternes T.A. Analytical methods for the determination of pharmaceuticals in aqueous environmental samples. Trends Anal. Chem. 20 (2001) 419-434
10. Rodríguez I., Quintana J.B., Carpinteiro J., Carro A.M., Lorenzo R.A., and Cela R. Determination of acidic drugs in sewage water by gas chromatography-mass spectrometry as tert.-butyldimethylsilyl derivatives. J. Chromatogr. A 985 (2003) 265-274
11. Weigel S., Kallenborn R., and Hühnerfuss H. Simultaneous solid-phase extraction of acidic, neutral and basic pharmaceuticals from aqueous samples at ambient (neutral) pH and their determination by gas chromatography-mass spectrometry. J. Chromatogr. A 1023 (2004) 183-195
12. Gros M., Petrovic M., and Barceló D. Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters. Talanta 70 (2006) 678-690
13. Verenitch S.S., Lowe C.J., and Mazumder A. Determination of acidic drugs and caffeine in municipal wastewaters and receiving waters by gas chromatography-ion trap tandem mass spectrometry. J. Chromatogr. A 1116 (2006) 193-203
14. Vieno N., Tuhkanen T., and Kronberg L. Analysis of neutral and basic pharmaceuticals in sewage treatment plants and in recipient rivers using solid phase extraction and liquid chromatography-tandem mass spectrometry detection. J. Chromatogr. A 1134 (2006) 101-111
15. Baugros J.-B., Giroud B., Dessalces G., Grenier-Loustalot M.-F., and Cren-Oliv C. Multiresidue analytical methods for the ultra-trace quantification of 33 priority substances present in the list of REACH in real water samples. Anal. Chim. Acta 607 (2008) 191-203
16. Sebo{double acute}k Á., Vasanits-Zsigrai A., Palkó Gy., Záray Gy., and Molnár-Perl I. Identification and quantification of ibuprofen, naproxen, ketoprofen and diclofenac present in waste-waters, as their trimethylsilyl derivatives, by gas chromatography mass spectrometry. Talanta 76 (2008) 642-650
17. d) for pharmaceuticals and musk fragrances in sewage sludge. Water Res. 38 (2004) 4075-4084
18. d) for pharmaceuticals, estrogens and musk fragrances in digested sludge. Water Res. 42 (2008) 287-295
19. Beausse J. Selected drugs in solid matrices: a review of environmental determination, occurrence and properties of principal substances. Trends Anal. Chem 23 (2004) 753-761
20. Göbel A., Thomson A., McArdell C.S., Alder A.C., Giger W., Theiss N., Löffer D., and Ternes T.A. Extraction and determination of sulfonamides, macrolides, and trimetoprim in sewage sludge. J Chromatogr A 1085 (2005) 179-189
21. 2 for quantifying trace amounts of pharmaceutical compounds in soil and sediment matrices. Trends Anal. Chem. 24 (2005) 635-644
22. Ternes T.A., Bonerz M., Herrmann N., Löffler D., Keller E., Lacida B.B., and Alder A.C. Determination of pharmaceuticals, iodinated contrast media and musk fragrances in sludge by LC/tandem MS and GC/MS. J. Chromatogr. A 1067 (2005) 213-223
23. Nieto A., Borrull F., Marcé R.M., and Pocurull E. Determination of personal care products in sewage sludge by pressurized liquid extraction and ultra high performance liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 1216 (2009) 5619-5625
24. Harrison E.Z., Oakes S.R., Hysell M., and Hay A. Organic chemicals in sewage sludge. Sci. Total Environ. 367 (2006) 481-497
25. Buchberger W.W. Novel analytical procedures for screening of drug residues in water, waste water, sediment and sludge. Anal. Chim. Acta 593 (2007) 129-139
26. Xu J., Wu L., Chen W., and Chang A.C. Simultaneous determination of pharmaceuticals, endocrine disrupting compounds and hormone in soils by gas chromatography-mass spectrometry. J. Chromatogr. A 1202 (2008) 189-195
27. Löffer D., and Ternes T.A. Determination of acidic pharmaceuticals, antibiotics and ivermectin in river sediment using liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 1021 (2003) 133-144
28. Bossio J.P., Harry J., Chad A., and Kinney C.A. Application of ultrasonic assisted extraction of chemically diverse organic compounds from soils and sediments. Chemosphere 70 (2008) 858-864
29. Parera J., Santos F.J., and Galceran M.T. Microwave-assisted extraction versus Soxhlet extraction for the analysis of short-chain chlorinated alkanes in sediments. J Chromatogr A 1046 (2004) 19-26
30. Liu R., Zhou J.L., and Wilding A. Microwave-assisted extraction followed by gas chromatography-mass spectrometry for the determination of endocrine disrupting chemicals in river sediments. J. Chromatogr. A 1038 (2004) 19-26
31. Morales S., Canosa P., Rodríguez I., Rubí E., and Cela R. Microwave assisted extraction followed by gas chromatography with tandem mass spectrometry for determination of triclosan and two related chlorophenols in sludge and sediments. J. Chromatogr. A 1082 (2005) 128-135
32. Prat M.D., Ramil D., Compano R., Hernandez-Arteseros J.A., and Granados M. Determination of flumequine and oxolinic acid in sludge sediments and soils by microwave-assisted extraction and liquid chromatography-fluorescence. Anal. Chim. Acta 567 (2006) 229-235
33. Rice S.L., and Mitra S. Microwave-assisted solvent extraction of solid matrices and subsequent detection of pharmaceuticals and personal care products (PPCPs) using gas chromatography-mass spectrometry. Anal. Chim. Acta 589 (2007) 125-132
34. Zuloaga O., Etxebarria N., Fernández L.A., and Madariaga J.M. Comparison of accelerated solvent extraction with microwave-assisted extraction and Soxhlet for the extraction of chlorinated biphenyls in soil samples. Trends Anal. Chem. 17 (1998) 642-647
35. Flotron V., Houessou J., Bosio A., Delteil C., Bermond A., and Camel V. Rapid determination of polycyclic aromatic hydrocarbons in sewage sludge using microwave-assisted solvent extraction. Comparison with other extraction methods. J. Chromatogr. A 999 (2003) 175-184
36. Díaz-Cruz M.S., López de Alda M.J., and Barceló D. Environmental behavior and analysis of veterinary and human drugs in soils, sediments and sludge. Trends Anal. Chem. 22 (2003) 340-351
37. Picó Y., Fernández M., Jose Ruiz M., and Font G. Current trends in solid-phase-based extraction techniques for the determination of pesticides in food and environment. J. Biochem. Biophys. Methods 70 (2007) 117-131
38. Barker S.A. Matrix solid phase dispersion (MSPD). J. Biochem. Biophys. Methods 70 (2007) 151-162
39. Plössl F., Giera M., and Bracher F. Multiresidue analytical method using dispersive solid-phase extraction and gas chromatography/ion trap mass spectrometry to determine pharmaceuticals in whole blood. J Chromatogr A 1135 (2006) 19-26
40. Díez C.C., Traag W.A., Zommer P., Marinero P., and Atienza J. Comparison of an acetonitrile extraction/partitioning and "dispersive solid-phase extraction" method with classical multi-residue methods for the extraction of herbicide residues in barley samples. J. Chromatogr. A 1131 (2006) 11-23
41. Koesukwiwata U., Sanguankaewa K., and Leepipatpiboon N. Rapid determination of phenoxy acid residues in rice by modified QuEChERS extraction and liquid chromatography-tandem mass spectrometry. Anal. Chim. Acta 626 (2008) 10-20