Protein adsorption in porous adsorbent particles: A multiscale modeling study on inner radial humps in the concentration profiles of adsorbed protein induced by nonuniform ligand density distributions

Journal of Separation Science

Volumn 32, Issue 18, 2009, Pages 3084-3098

  Riccardi, Enrico ^a   Wang, Jee Ching ^a   Liapis, Athanasios I ^a  

^a University of Missouri Rolla   (United States)

Author keywords

Inner radial humps; Molecular dynamics modeling and simulations; Multiscale modeling; Nonuniform ligand density distributions; Protein adsorption

Indexed keywords

LIGAND DENSITY; MOLECULAR DYNAMICS MODELING; MULTI-SCALE MODELING; NONUNIFORM; PROTEIN ADSORPTION;

ADSORPTION; CONCENTRATION (PROCESS); CONTINUUM MECHANICS; ION EXCHANGE; IONIC STRENGTH; MOLECULAR DYNAMICS; POROUS MATERIALS; PROTEINS; QUALITY ASSURANCE; QUALITY CONTROL; QUALITY FUNCTION DEPLOYMENT; SIMULATORS; SIZE DISTRIBUTION; TOTAL QUALITY MANAGEMENT;

LIGANDS;

LIGAND; PROTEIN;

ADSORPTION KINETICS; ARTICLE; CONCENTRATION (PARAMETERS); CONFOCAL LASER MICROSCOPY; DENSITY; DIFFUSION COEFFICIENT; IMMOBILIZATION; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; POROSITY; PRIORITY JOURNAL;

ADSORPTION; BIOCATALYSIS; COMPUTER SIMULATION; FREE RADICALS; HYDROGEN-ION CONCENTRATION; LIGANDS; MODELS, CHEMICAL; OSMOLAR CONCENTRATION; PARTICLE SIZE; POROSITY; PROTEINS; SURFACE PROPERTIES;

EID: 70450195310     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900180     Document Type: Article

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