Thermal isomerization of cannabinoid analogues

Journal of the American Chemical Society

Volumn 131, Issue 46, 2009, Pages 16640-16641

  Garcia, Angie ^a   Borchardt, Dan ^a   Chang, Chia En A ^a   Marsella, Michael J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOIDS; CHEMICAL EQUATIONS; DENSITY FUNCTIONAL THEORY CALCULATIONS; IN-SILICO; RECEPTOR BINDING; THERMAL ISOMERIZATIONS;

BINDING ENERGY; ELECTRON TRANSITIONS; ISOMERIZATION; ISOMERS;

DENSITY FUNCTIONAL THEORY;

CANNABICHROMENE; CANNABINOID 1 RECEPTOR; TETRAHYDROCANNABINOL;

ARTICLE; COMPUTER MODEL; DENSITY FUNCTIONAL THEORY; DRUG CONFORMATION; DRUG METABOLISM; DRUG RECEPTOR BINDING; HEAT TREATMENT; ISOMERIZATION; MOLECULAR DOCKING; MOLECULAR MECHANICS; NONHUMAN; RECEPTOR AFFINITY; STEREOISOMERISM;

CANNABINOIDS; HOT TEMPERATURE; ISOMERISM; TETRAHYDROCANNABINOL;

EID: 70450175403     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja907062v     Document Type: Article

References (11)

1. Mechoulam, R. Br. J. Pharmacol. 2005, 146, 913-915.
2. Pacher, P.; Batkai, S.; Kunos, G. Pharmacol. Rev. 2006, 58, 389-462.
3. Evans, D. A.; Shaughnessy, E. A.; Barnes, D. M. Tetrahedron Lett. 1997, 38, 3193-3194.
4. Trost, B. M.; Dogra, K. Org. Lett. 2007, 9, 861-863.
5. Mechoulam, R; Gaoni, Y. J. Am. Chem. Soc. 1965, 87, 3273-3275.
6. Marijuana: Chemistry, Pharmacology, Metabolism and Clinical Effects; Mechoulam, R., Ed.; Academic Press: New York, 1973.
7. Tietze, L. F. Chem. Rev. 1996, 96, 115-136.
8. Tietze, L. F.; Vonkiedrowski, G.; Berger, B. Synthesis 1982, 683-684.
9. Malerich, J. P.; Maimone, T. J.; Elliott, G. I.; Trauner, D. J. Am. Chem. Soc. 2005, 127, 6276-6283.
10. Salo, O. M. H.; Lahtela-Kakkonen, M.; Gynther, J.; Jarvinen, T.; Poso, A. J. Med. Chem. 2004, 47, 3048-3057.
11. Picone, R. P.; Khanolkar, A. D.; Xu, W.; Ayotte, L. A.; Thakur, G. A.; Hurst, D. P.; Abood, M. E.; Reggio, P. H.; Fournier, D. J.; Makriyannis, A. Mol. Pharmacol. 2005, 68, 1623-1635.