Effect of adipose tissue on the sexual dimorphism in metabolic flexibility

Metabolism: Clinical and Experimental

Volumn 58, Issue 11, 2009, Pages 1564-1571

  Sparks, Lauren M ^a   Pasarica, Magdalena ^a   Sereda, Olga ^a   deJonge, Lilian ^a   Thomas, Shantele ^a   Loggins, Heather ^a   Xie, Hui ^a   Miles, John M ^b   Smith, Steven R ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; ADIPONECTIN; ANTIDIABETIC AGENT; DNA; FAT; GLUCOSE; INSULIN; RNA;

ABDOMINAL FAT; ADIPOGENESIS; ADIPOSE TISSUE; ADULT; ARTICLE; FATTY ACID OXIDATION; FEMALE; GENE EXPRESSION; GLUCOSE OXIDATION; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; LIPID METABOLISM; LIPID STORAGE; LIPID TRANSPORT; MALE; METABOLIC CAPACITY; METABOLIC FLEXIBILITY; NORMAL HUMAN; PRIORITY JOURNAL; RESPIRATORY QUOTIENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; ADIPOCYTE; ANAEROBIC THRESHOLD; BIOSYNTHESIS; BLOOD; BODY COMPOSITION; CALORIMETRY; CELL SIZE; GLUCOSE CLAMP TECHNIQUE; HISTOLOGY; ISOLATION AND PURIFICATION; METABOLISM; ORGAN SIZE; OXIDATION REDUCTION REACTION; PHYSIOLOGY; POSTMENOPAUSE; SEXUAL DEVELOPMENT; ULTRASTRUCTURE;

ADIPOCYTES; ADIPONECTIN; ADIPOSE TISSUE; ADULT; ANAEROBIC THRESHOLD; BODY COMPOSITION; CALORIMETRY, INDIRECT; CELL SIZE; DNA; FATS; FEMALE; GENE EXPRESSION; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; METABOLISM; ORGAN SIZE; OXIDATION-REDUCTION; POSTMENOPAUSE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SEX CHARACTERISTICS; YOUNG ADULT;

EID: 70449723308     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2009.05.008     Document Type: Article

References (37)

1. Storlien L., Oakes N.D., and Kelley D.E. Metabolic flexibility. Proc Nutr Soc 63 (2004) 363-368
2. Kelley D.E., Goodpaster B., Wing R.R., and Simoneau J.A. Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am J Physiol 277 (1999) E1130-E1141
3. Frayn K.N. Adipose tissue as a buffer for daily lipid flux. Diabetologia 45 (2002) 1201-1210
4. Hickner R.C., Racette S.B., Binder E.F., Fisher J.S., and Kohrt W.M. Suppression of whole body and regional lipolysis by insulin: effects of obesity and exercise. J Clin Endocrinol Metab 84 (1999) 3886-3895
5. Odegaard J.I., Ricardo-Gonzalez R.R., Goforth M.H., Morel C.R., Subramanian V., Mukundan L., et al. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 447 (2007) 1116-1120
6. Clement K., Viguerie N., Poitou C., Carette C., Pelloux V., Curat C.A., et al. Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects. FASEB J 18 (2004) 1657-1669
7. Cancello R., and Clement K. Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue. BJOG 113 (2006) 1141-1147
8. Kern P.A., Di Gregorio G.B., Lu T., Rassouli N., and Ranganathan G. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes 52 (2003) 1779-1785
9. Jensen M.D. Lipolysis: contribution from regional fat. Annu Rev Nutr 17 (1997) 127-139
10. Wahrenberg H., Lonnqvist F., and Arner P. Mechanisms underlying regional differences in lipolysis in human adipose tissue. J Clin Invest 84 (1989) 458-467
11. Levadoux E., Morio B., Montaurier C., Puissant V., Boirie Y., Fellmann N., et al. Reduced whole-body fat oxidation in women and in the elderly. Int J Obes Relat Metab Disord 25 (2001) 39-44
12. Nagy T.R., Goran M.I., Weinsier R.L., Toth M.J., Schutz Y., and Poehlman E.T. Determinants of basal fat oxidation in healthy Caucasians. J Appl Physiol 80 (1996) 1743-1748
13. Bottner A., Kratzsch J., Muller G., Kapellen T.M., Bluher S., Keller E., et al. Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels. J Clin Endocrinol Metab 89 (2004) 4053-4061
14. Leibel R.L., and Hirsch J. Site- and sex-related differences in adrenoreceptor status of human adipose tissue. J Clin Endocrinol Metab 64 (1987) 1205-1210
15. Sparks L.M., Xie H., Koza R.A., Mynatt R., Bray G.A., and Smith S.R. High-fat/low-carbohydrate diets regulate glucose metabolism via a long-term transcriptional loop. Metabolism 55 (2006) 1457-1463
16. Sparks L.M., Xie H., Koza R.A., Mynatt R.L., Hulver M.W., Bray G., et al. A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes 54 (2005) 1926-1933
17. Ukropcova B., McNeil M., Sereda O., de Jonge L., Xie H., Bray G.A., et al. Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor. J Clin Invest 115 (2005) 1934-1941
18. Heilbronn L.K., Rood J., Janderova L., Albu J.B., Kelley D.E., Ravussin E., et al. Relationship between serum resistin concentrations and insulin resistance in nonobese, obese, and obese diabetic subjects. J Clin Endocrinol Metab 89 (2004) 1844-1848
19. Carter H., Jones A.M., Barstow T.J., Burnley M., Williams C.A., and Doust J.H. Oxygen uptake kinetics in treadmill running and cycle ergometry: a comparison. J Appl Physiol 89 (2000) 899-907
20. Livesey G., and Elia M. Food energy values of artificial feeds for man. Clin Nutr 4 (1985) 99-111
21. Smith S.R., Xie H., Baghian S., Needham A., McNeil M., Bogacka I., et al. Pioglitazone changes the distribution of adipocyte size in type 2 diabetics. Adipocytes 2 (2006) 11-22
22. Miles J.M., Ellman M.G., McClean K.L., and Jensen M.D. Validation of a new method for determination of free fatty acid turnover. Am J Physiol 252 (1987) E431-E438
23. Bustin S.A. Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol 25 (2000) 169-193
24. Smith S.R., Lovejoy J.C., DeLaney J.P., Ruyter I., and McNeil M. The inhibition of glycogen synthesis by fatty acids is not mediated by inhibition of extracellular signal-regulated kinase 1/2. Diabetologia 42 (1999) 1031-1032
25. Ruan H., and Lodish H.F. Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines. Curr Opin Lipidol 15 (2004) 297-302
26. Lumeng C.N., Bodzin J.L., and Saltiel A.R. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117 (2007) 175-184
27. Bouchard C., Despres J.P., and Mauriege P. Genetic and nongenetic determinants of regional fat distribution. Endocr Rev 14 (1993) 72-93
28. Leibel R.L., Edens N.K., and Fried S.K. Physiologic basis for the control of body fat distribution in humans. Annu Rev Nutr 9 (1989) 417-443
29. Jernas M., Palming J., Sjoholm K., Jennische E., Svensson P.A., Gabrielsson B.G., et al. Separation of human adipocytes by size: hypertrophic fat cells display distinct gene expression. FASEB J 20 (2006) 1540-1542
30. Ong K.K., Frystyk J., Flyvbjerg A., Petry C.J., Ness A., and Dunger D.B. Sex-discordant associations with adiponectin levels and lipid profiles in children. Diabetes 55 (2006) 1337-1341
31. Lumeng C.N., Deyoung S.M., and Saltiel A.R. Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins. Am J Physiol Endocrinol Metab 292 (2006) E166-E174
32. MacDougald O.A., and Lane M.D. Transcriptional regulation of gene expression during adipocyte differentiation. Annu Rev Biochem 64 (1995) 345-373
33. Beale E.G., Hammer R.E., Antoine B., and Forest C. Glyceroneogenesis comes of age. FASEB J 16 (2002) 1695-1696
34. Reshef L., Olswang Y., Cassuto H., Blum B., Croniger C.M., Kalhan S.C., et al. Glyceroneogenesis and the triglyceride/fatty acid cycle. J Biol Chem 278 (2003) 30413-30416
35. Sampath H., and Ntambi J.M. Stearoyl-coenzyme A desaturase 1, sterol regulatory element binding protein-1c and peroxisome proliferator-activated receptor-alpha: independent and interactive roles in the regulation of lipid metabolism. Curr Opin Clin Nutr Metab Care 9 (2006) 84-88
36. Peterfy M., Phan J., Xu P., and Reue K. Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin. Nat Genet 27 (2001) 121-124
37. Campbell S.E., and Febbraio M.A. Effects of ovarian hormones on exercise metabolism. Curr Opin Clin Nutr Metab Care 4 (2001) 515-520