Keratins and protein synthesis: The plot thickens

Journal of Cell Biology

Volumn 187, Issue 2, 2009, Pages 157-159

  Kellner, Juliane C ^a   Coulombe, Pierre A ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KERATIN TYPE II; ADENYLATE KINASE; CARRIER PROTEIN; GLUCOSE TRANSPORTER; RAPTOR PROTEIN, MOUSE;

CELL TYPE; CHROMOSOME 11; CHROMOSOME 15; CHROMOSOME REARRANGEMENT; EMBRYONIC STEM CELL; GENE CLUSTER; GENE SEQUENCE; HOMEOSTASIS; KERATINOCYTE; MICROTUBULE ASSEMBLY; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; ANIMAL; GENETICS; HUMAN; METABOLISM; MOUSE;

MUS;

ADENYLATE KINASE; ANIMALS; CARRIER PROTEINS; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; HUMANS; KERATINS, TYPE II; MICE; PROTEIN BIOSYNTHESIS;

EID: 70449714187     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200909134     Document Type: Note

References (21)

1. Adams, D.J., P.J. Biggs, T. Cox, R. Davies, L. van der Weyden, J. Jonkers, J. Smith, B. Plumb, R. Taylor, I. Nishijima, et al. 2004. Mutagenic insertion and chromosome engineering resource (MICER). Nat. Genet. 36:867-871. doi:10.1038/ng1388
2. Adams, D.J., M.A. Quail, T. Cox, L. van der Weyden, B.D. Gorick, Q. Su, W.I. Chan, R. Davies, J.K. Bonfield, F. Law, et al. 2005. A genome-wide, endsequenced 129Sv BAC library resource for targeting vector construction. Genomics. 86:753-758. doi:10.1016/j.ygeno.2005.08.003
3. Ameen, N.A., Y. Figueroa, and P.J. Salas. 2001. Anomalous apical plasma membrane phenotype in CK8-deficient mice indicates a novel role for intermediate filaments in the polarization of simple epithelia. J. Cell Sci. 114:563-575.
4. Baribault, H., J. Price, K. Miyai, and R.G. Oshima. 1993. Mid-gestational lethality in mice lacking keratin 8. Genes Dev. 7:1191-1202. doi:10.1101/gad .7.7a.1191
5. Baribault, H., J. Penner, R.V. Iozzo, and M. Wilson-Heiner. 1994. Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev. 8:2964-2973. doi:10.1101/gad.8.24.2964
6. Bocquet, A., R. Berges, R. Frank, P. Robert, A.C. Peterson, and J. Eyer. 2009. Neurofilaments bind tubulin and modulate its polymerization. J. Neurosci. 29:11043-11054. doi:10.1523/JNEUROSCI.1924-09.2009
7. Galarneau, L., A. Loranger, S. Gilbert, and N. Marceau. 2007. Keratins modulate hepatic cell adhesion, size and G1/S transition. Exp. Cell Res. 313:179-194. doi:10.1016/j.yexcr.2006.10.007
8. Hesse, M., T. Franz, Y. Tamai, M.M. Taketo, and T.M. Magin. 2000. Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality. EMBO J. 19:5060-5070. doi:10.1093/emboj/19.19.5060
9. Kerns, M.L., D. DePianto, A.T. Dinkova-Kostova, P. Talalay, and P.A. Coulombe. 2007. Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex. Proc. Natl. Acad. Sci. USA. 104:14460-14465. doi:10.1073/pnas.0706486104
10. Kim, S., and P.A. Coulombe. 2007. Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm. Genes Dev. 21:1581-1597. doi:10.1101/gad.1552107
11. Kim, S., P. Wong, and P.A. Coulombe. 2006. A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature. 441:362-365. doi:10.1038/nature04659
12. Kim, S., J. Kellner, C.H. Lee, and P.A. Coulombe. 2007. Interaction between the keratin cytoskeleton and eEF1Bgamma affects protein synthesis in epithelial cells. Nat. Struct. Mol. Biol. 14:982-983. doi:10.1038/nsmb1301
13. Liu, P., N.A. Jenkins, and N.G. Copeland. 2003. A highly efficient recombineeringbased method for generating conditional knockout mutations. Genome Res. 13:476-484. doi:10.1101/gr.749203
14. McGowan, K.M., X. Tong, E. Colucci-Guyon, F. Langa, C. Babinet, and P.A. Coulombe. 2002. Keratin 17 null mice exhibit age- and strain-dependent alopecia. Genes Dev. 16:1412-1422. doi:10.1101/gad.979502
15. Oriolo, A.S., F.A. Wald, G. Canessa, and P.J. Salas. 2007. GCP6 binds to intermediate filaments: a novel function of keratins in the organization of microtubules in epithelial cells. Mol. Biol. Cell. 18:781-794. doi:10.1091/ mbc.E06-03-0201
16. Ramírez-Solis, R., P. Liu, and A. Bradley. 1995. Chromosome engineering in mice. Nature. 378:720-724. doi:10.1038/378720a0
17. Schweizer, J., P.E. Bowden, P.A. Coulombe, L. Langbein, E.B. Lane, T.M. Magin, L. Maltais, M.B. Omary, D.A. Parry, M.A. Rogers, and M.W. Wright. 2006. New consensus nomenclature for mammalian keratins. J. Cell Biol. 174:169-174. doi:10.1083/jcb.200603161
18. Tamai, Y., T. Ishikawa, M.R. Bösl, M. Mori, M. Nozaki, H. Baribault, R.G. Oshima, and M.M. Taketo. 2000. Cytokeratins 8 and 19 in the mouse placental development. J. Cell Biol. 151:563-572. doi:10.1083/jcb .151.3.563
19. Toivola, D.M., S. Krishnan, H.J. Binder, S.K. Singh, and M.B. Omary. 2004. Keratins modulate colonocyte electrolyte transport via protein mistargeting. J. Cell Biol. 164:911-921.
20. Toivola, D.M., G.Z. Tao, A. Habtezion, J. Liao, and M.B. Omary. 2005. Cellular integrity plus: organelle-related and protein-targeting functions of intermediate filaments. Trends Cell Biol. 15:608-617. doi:10.1016/j.tcb .2005.09.004
21. Vijayraj, P., C. Kröger, U. Reuter, R. Windoffer, R.E. Leube, and T.M. Magin. 2009. Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor. J. Cell Biol. 187:175-184.