GCP6 binds to intermediate filaments: A novel function of keratins in the organization of microtubules in epithelial cells

Molecular Biology of the Cell

Volumn 18, Issue 3, 2007, Pages 781-794

  Oriolo, Andrea S ^a   Wald, Flavia A ^a   Canessa, Gisella ^a   Salas, Pedro J I ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BINDING PROTEIN; CYCLIN DEPENDENT KINASE 1; GAMMA TUBULIN; KERATIN; MUTANT PROTEIN; PROTEIN GCP6; PROTEIN SUBUNIT; SERINE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING ASSAY; BINDING COMPETITION; CELL ADHESION; CELL STRAIN CACO 2; CENTROSOME; CONTROLLED STUDY; CYTOARCHITECTURE; CYTOPLASM; CYTOSKELETON; HUMAN; HUMAN CELL; INTERMEDIATE FILAMENT; INTESTINE EPITHELIUM CELL; KNOCKOUT GENE; MICROTUBULE ORGANIZING CENTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM;

ANIMALS; CDC2 PROTEIN KINASE; CELL POLARITY; CERCOPITHECUS AETHIOPS; COS CELLS; DOWN-REGULATION; EPITHELIAL CELLS; HISTONES; HUMANS; INTERMEDIATE FILAMENTS; KERATINS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULE-ORGANIZING CENTER; MICROTUBULES; MUTATION; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TUBULIN;

EID: 33947177148     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E06-03-0201     Document Type: Article

References (45)

1. Ameen, N. A., Figueroa, Y., and Salas, P.J.I. (2001). Anomalous apical plasma membrane phenotype in CK8-deficient mice indicates a novel role for intermediate filaments in the polarization of simple epithelia. J. Cell Sci. 114, 563-575.
2. Apodaca, G., Katz, L. A., and Mostov, K. E. (1994). Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes. J. Cell Biol. 125, 67-86.
3. Bacallao, R., Antony, C., Dotti, C., Karsenti, E., Stelzer, E.H.K., and Simons, K. (1989). The subcellular organization of Madin-Darby Canine kidney cells during the formation of a polarized epithelium. J. Cell Biol. 109, 2817-2832.
4. Baribault, H., Penner, J., Iozzo, R. V., and Wilson-Heiner, M. (1994). Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev. 8, 2964-2973.
5. Blouin, R., Kawahara, H., French, S. W., and Marceau, N. (1990). Selective accumulation of IF proteins at a focal juxtanuclear site in COS-1 cells transfected with mouse keratin 18 cDNA. Exp. Cell Res. 187, 234-242.
6. Bobinnec, Y., Fukuda, M., and Nishida, E. (2000). Identification and characterization of Caenorhabditis elegans gamma-tubulin in dividing cells and differentiated tissues. J. Cell Sci. 113, 3747-3759.
7. Bré, M. H., Pepperkok, R., Hill, A. M., Levilliers, N., Ansorge, W., Stelzer, E. H., Karsent, I. E. (1990). Regulation of microtubule dynamics and nucleation during polarization in MDCK II cells. J. Cell Biol. 111, 3013-3021.
8. Buendia, B., Bré, M. H., Griffiths, G., and Karsenti, E. (1990). Cytoskeletal control of centrioles movement during the establishment of polarity in MDCK cells. J. Cell Biol. 110, 1123-1135.
9. Cheng, Z. M., and Wang, H. L. (2004). Alteration of cytokeratin 7 and cytokeratin 20 expression profile is uniquely associated with tumorigenesis of primary adenocarcinoma of the small intestine. Am J. Surg. Pathol. 28, 1352-1359.
10. Dictenberg, J. B., Zimmerman, W., Sparks, C. A., Young, A., Vidair, C., Zheng, Y., Carrington, W., Fay, F. S., and Doxsey, S. J. (1998). Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome. J. Cell Biol. 141, 163-174.
11. cdc2 mediated phosphorylation mobilizes microtubule organizing centers from the apical intermediate filament scaffold in Caco-2 epithelial cells. J. Biol. Chem. 277, 37848-37854.
12. Fujita, A., Vardy, L., Garcia, M. A., and Toda, T. (2002). A fourth component of the fission yeast gamma-tubulin complex, Alp16, is required for cytoplasmic microtubule integrity and becomes indispensable when gamma-tubulin function is compromised. Mol. Biol. Cell 13, 2360-2373.
13. Gueth-Hallonet, C., Antony, C., Aghion, J., Santa-Maria, A., Lajore-Mazenc, I., Wright, M., and Maro, B. (1993). γ-tubulin is present in acentriolar MTOCs during early mouse development. J. Cell Sci. 105, 157-166.
14. cdc2 and p33Cdk2. J. Biol. Chem. 271, 25240-25246.
15. Ito, H., Fukada, Y., Jurata, K., and Kimura, A. (1983). Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168.
16. Jeng, R., and Stearns, T. (1999). Gamma-tubulin complexes: size does matter. Trends Cell Biol. 9, 339-342.
17. Keating, T. J., and Borisy, G. G. (2000). Immnostructural evidence for the template mechanism of microtubule nucleation. Nat. Cell Biol. 2, 352-357.
18. Keating, T. J., Peloquin, J. G., Rodionov, V. I., Momcilovic, D., and Borisy, G. G. (1997). Microtubule release from the centrosome. Proc. Natl. Acad. Sci. USA 94, 5078-5083.
19. Komarova, Y. A., and Vorobjev, I. A. (1993). Ultrastructural changes in the cell center during enterocyte differentiation in the mouse. Tsitologiia 35, 36-43.
20. Lane, E. B., Goodman, S. L., and Trejdosiewicz, L. K. (1982). Disruption of the keratin filament network during epithelial cell division. EMBO J. 1, 1365-1372.
21. Meads, T., and Schroer, T. A. (1995). Polarity and nucleation of microtubules in polarized epithelial cells. Cell Motil. Cytoskeleton 32, 273-288.
22. Moll, R., Franke, W. W., and Schiller, D. L. (1982). The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31, 11-24.
23. Mogensen, M. M., Mackie, J. B., Doxsey, S. J., Stearns, T., and Tucker, J. B. (1997). Centrosomal development of γ-tubulin and pericentrin: evidence for a microtubule-nucleating domain and a minus-end docking domain in certain mouse epithelial cells. Cell Motil. Cytoskeleton 36, 276-290.
24. Mogensen, M. M., Malik, A., Piel, M., Bouckson-Castaing, V., and Bornens, M. (2000). Microtubule minus-end anchorage at centrosomal and non-centrosomal sites: the role of ninein. J. Cell Sci. 113, 3013-3023.
25. Mogensen, M. M., Tucker, J. B., and Stebbins, H. (1989). Microtubule polarities indicate that nucleation and capture of microtubules occurs at cell surfaces in Drosophila. J. Cell Biol. 108, 1445-1452.
26. Moritz, M., Braunfeld, M. B., Guénebaut, V., Heuser, J., and Agard, D. A. ( 2000). Structure of the γ-tubulin ring complex: a template for microtubule nucleation. Nat. Cell Biol. 365-370.
27. Mulari, M. T., Patrikainen, L., Kaisto, T., Metsikko, K., Salo, J. J., and Vaananen, H. K. (2003). The architecture of microtubular network and Golgi orientation in osteoclasts-major differences between avian and mammalian species. Exp. Cell Res. 285, 221-235.
28. Murphy, S. M., Preble, A. M., Patel, U. K., O'Connell, K. L., Dias, D. P., Moritz, M., Agard, D., Stults, J. T., and Stearns, T. (2001). GCP5 and GCP 6, Two New Members of the Human γ-Tubulin Complex. Mol. Biol. Cell 12, 3340-3352.
29. Pinto, M., et al. (1983). Enterocyte-like differentiation and polarization of the iuman colon carcinoma cell line Caco-2 in culture. Biol. Cell 47, 323-330.
30. Pockwinse, S. M., Krockmalnic, G., Doxsey, S. J., Nickerson, J., Lian, J. B., van Wijnen, A. J., Stein, J. L., Stein, G. S., and Penman, S. (1997). Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold. Proc. Natl. Acad. Sci. USA 94, 3022-3027.
31. Ramaekers, F., Huysmans, A., Schaart, G., Moesker, O., and Vooijs, P. (1987). Tissue distribution of keratin 7 as monitored by a monoclonal antibody. Exp. Cell Res. 170(1), 235-249.
32. Reilein, A., Yamada, S., and Nelson, W. J. (2005). Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells. J. Cell Biol. 71(5), 845-855.
33. Rizzolo, L. J., and Joshi, H. C. (1993). Apical orientation of the microtubule organizing center and associated gamma-tubulin during the polarization of the retinal pigment epithelium in vivo. Dev. Biol. 157, 147-156.
34. Salas, P.J.I. (1999). Insoluble γ-Tubulin-containing structures are anchored to the apical network of intermediate filaments in polarized CACO-2 epithelial cells. J. Cell Biol. 146, 645-658.
35. Steinert, P., Zackroff, R., Aynardi-Whitman, M., and Goldman, R. D. (1982). Isolation and characterization of intermediate filaments. Methods Cell Biol. 24, 399-419.
36. Szollosi, A., Ris, H., Szollosi, D., and Debec, A. (1986). A centriole-free Drosophila cell line. A high voltage EM study. Eur. J. Cell Biol. 40, 100-104.
37. Trevor, K. T., McGuire, J. G., and Leonova, E. V. (1995). Association of vimentin intermediate filaments with the centrosome. J. Cell Sci. 108, 343-356.
38. Tsushimi, T., Noshima, S., Oga, A., Esato, K., and Sasaki, K. (2001). DNA amplification and chromosomal translocations are accompanied by chromosomal instability: analysis of seven human colon cancer cell lines by comparative genomic hybridization and spectral karyotyping. Cancer Genet Cytogenet. 126, 34-38.
39. Vorobjev, I. A., Svitikina, T. M., and Borisy, G. G. (1997). Cytoplasmic assembly of microtubules in cultured cells. J. Cell Sci. 110, 2635-2645.
40. Urbani, L., and Stearns, T. (1999). The centrosome. Curr. Biol. 9, R315-R317.
41. Wald, F. A., Figueroa, Y., Oriolo, A. S., and Salas, P.J.I. (2003). Membrane repolarization is delayed in proximal tubules after ischemia/reperfusion: possible role of Microtubule-Organizing Centers. Am. J. Physiol. 285, F230-F240.
42. Wald, F. A., Oriolo, A. S., Casanova, M. L., and Salas, P.J.I. (2005). Intermediate filaments recruit dormant ezrin: a mechanism for apical localization in intestinal epithelial cells. Mol. Biol. Cell 16, 4096-4107.
43. Wiese, C., and Zheng, Y. (2000). A new function for the gamma-tubulin ring complex as a microtubule minus-end cap. Nat. Cell Biol. 2, 358-364.
44. Yvon, A.-M.C., and Wadsworth, P. (1997). Non-centrosomal microtubule formation and measurement of minus end microtubule dynamics in A498 cells. J. Cell Sci. 110, 2391-2401.
45. Zhang, L., Keating, T. J., Wilde, A., Borisy, G. G., and Zheng, Y. (2000). The role of Xgrip210 in gamma-tubulin ring complex assembly and centrosome recruitment. J. Cell Biol. 151, 1525-1536.