Mechanisms underlying perceptual learning of contrast detection in adults with anisometropic amblyopia

Journal of Vision

Volumn 9, Issue 11, 2009, Pages 1-14

  Huang, Chang Bing ^a   Lu, Zhong Lin ^a   Zhou, Yifeng ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Contrast detection; Contrast sensitivity; External noise exclusion; Internal noise reduction; Perceptual learning

Indexed keywords

ADOLESCENT; ADULT; AMBLYOPIA; ARTICLE; ARTIFACT; BIOLOGICAL MODEL; CONTRAST SENSITIVITY; DISCRIMINATION LEARNING; FEMALE; HUMAN; MALE; METHODOLOGY; NERVE CELL PLASTICITY; PATHOPHYSIOLOGY; PATTERN RECOGNITION; PERCEPTIVE THRESHOLD; PHOTOSTIMULATION; PHYSIOLOGY; VISION; VISUAL ACUITY;

ADOLESCENT; ADULT; AMBLYOPIA; ARTIFACTS; CONTRAST SENSITIVITY; DISCRIMINATION LEARNING; FEMALE; HUMANS; MALE; MODELS, NEUROLOGICAL; NEURONAL PLASTICITY; PATTERN RECOGNITION, VISUAL; PHOTIC STIMULATION; SENSORY THRESHOLDS; VISUAL ACUITY; VISUAL PERCEPTION; YOUNG ADULT;

EID: 70449711001     PISSN: None     EISSN: 15347362     Source Type: Journal    
DOI: 10.1167/9.11.1     Document Type: Article

References (69)

1. Barnes, G. R., Hess, R. F., Dumoulin, S. O., Achtman, R. L., & Pike, G. B. (2001). The cortical deficit in humans with strabismic amblyopia. The Journal of Physiology, 533, 281-297.
2. Birnbaum, M. H., Koslowe, K., & Sanet, R. (1977). Success in amblyopia therapy as a function of age: A literature survey. American Journal of Optometry and Physiological Optics, 54, 269-275.
3. Brainard, D. H. (1997). The Psychophysics Toolbox. Spatial Vision, 10, 433-436.
4. Campbell, F. W., Hess, R. F., Watson, P. G., & Banks, R. (1978). Preliminary results of a physiologically based treatment of amblyopia. British Journal of Ophthalmology, 62, 748-755.
5. Chandna, A., Pennefather, P. M., Kovacs, I., & Norcia, A. M. (2001). Contour integration deficits in anisometropic amblyopia. Investigative Ophthalmology and Vision Science, 42, 875-878.
6. Chung, S. T., Levi, D. M., & Tjan, B. S. (2005). Learning letter identification in peripheral vision. Vision Research, 45, 1399-1412.
7. Chung, S. T., Li, R. W., & Levi, D. M. (2006). Identification of contrast-defined letters benefits from perceptual learning in adults with amblyopia. Vision Research, 46, 3853-3861.
8. Ciuffreda, K. J., Goldner, K., & Connelly, R. (1980). Lack of positive results of a physiologically based treatment of amblyopia. British Journal of Ophthalmology, 64, 607-612.
9. Ciuffreda, K. J., Levi, D. M., & Selenow, A. (1991). Amblyopia: Basic and clinical aspects. Boston: Butterworth-Heinemann.
10. Daw, N. W. (1998). Critical periods and amblyopia. Archives of Ophthalmology, 116, 502-505.
11. Dosher, B. A., & Lu, Z.-L. (1998). Perceptual learning reflects external noise filtering and internal noise reduction through channel reweighting. Proceedings of the National Academy of Sciences of the United States of America, 95, 13988-13993.
12. Dosher, B. A., & Lu, Z. L. (1999). Mechanisms of perceptual learning. Vision Research, 39, 3197-3221.
13. Dosher, B., & Lu, Z.-L. (2005). Perceptual learning in clear not noisy displays optimizes performance: Asymmetry of transfer. Proceedings of the National Academy of Sciences of the United States of America, 102, 5286-5290.
14. Hays, W. L. (1988). Statistics. Fort Worth, TX: Holt, Rinehart & Winston.
15. Hess, R. F. (1982). Developmental sensory impairment: Amblyopia or tarachopia? Human Neurobiology, 1, 17-29.
16. Hess, R. F., & Field, D. J. (1994). Is the spatial deficit in strabismic amblyopia due to loss of cells or an uncalibrated disarray of cells? Vision Research, 34, 3397-3406.
17. Hess, R. F., & Holliday, I. E. (1992). The spatial localization deficit in amblyopia. Vision Research, 32, 1319-1339.
18. Hess, R. F., McIlhagga, W., & Field, D. J. (1997). Contour integration in strabismic amblyopia: The sufficiency of an explanation based on positional uncertainty. Vision Research, 37, 3145-3161.
19. Huang, C., Tao, L., Zhou, Y., & Lu, Z. L. (2007). Treated amblyopes remain deficient in spatial vision: A contrast sensitivity and external noise study. Vision Research, 47, 22-34.
20. Huang, C. B., Zhou, Y., & Lu, Z. L. (2008). Broad bandwidth of perceptual learning in the visual system of adults with anisometropic amblyopia. Proceedings of the National Academy of Science United States of America, 105, 4068-4073.
21. Kersten, D., Hess, R. F., & Plant, G. T. (1988). Assessing contrast sensitivity behind cloudy media. Clinical Vision Sciences, 143-158.
22. Kiorpes, L., Boothe, R. G., Hendrickson, A. E., Movshon, J. A., Eggers, H. M., & Gizzi, M. S. (1987). Effects of early unilateral blur on the macaque's visual system: I. Behavioral observations. Journal of Neuroscience, 7, 1318-1326.
23. Kiorpes, L., Kiper, D. C., O'Keefe, L. P., Cavanaugh, J. R., & Movshon, J. A. (1998). Neuronal correlates of amblyopia in the visual cortex of macaque monkeys with experimental strabismus and anisometropia. Journal of Neuroscience, 18, 6411-6424.
24. Kiorpes, L., & McKee, S. P. (1999). Neural mechanisms underlying amblyopia. Current Opinion in Neurobiology, 9, 480-486.
25. Kovacs, I., Polat, U., Pennefather, P. M., Chandna, A., & Norcia, A. M. (2000). A new test of contour integration deficits in patients with a history of disrupted binocular experience during visual development. Vision Research, 40, 1775-1783.
26. Kupfer, C. (1957). Treatment of amblyopia exanopsia in adults; a preliminary report of seven cases. American Journal of Ophthalmology, 43, 918-922.
27. Levi, D. M. (1991). Spatial vision in amblyopia. In R. D. (Ed.), Vision and visual dysfunciton, 10B (pp. 212-239). London: MacMillan Press.
28. Levi, D. M. (2005). Perceptual learning in adults with amblyopia: A reevaluation of critical periods in human vision. Developmental Psychobiology, 46, 222-232.
29. Levi, D.M., & Klein, S. A. (1985). Vernier acuity, crowding and amblyopia. Vision Research, 25, 979-991.
30. Levi, D. M., & Klein, S. A. (2003). Noise provides some new signals about the spatial vision of amblyopes. Journal of Neuroscience, 23, 2522-2526.
31. Levi, D. M., Klein, S. A., & Chen, I. (2008). What limits performance in the amblyopic visual system: Seeing signals in noise with an amblyopic brain. Journal of Vision, 8(4):1, 1-23, http://journalofvision.org/8/4/1/, doi:10.1167/8.4.1.
32. Levi, D. M., & Li, R. W. (2009a). Improving the performance of the amblyopic visual system. Philosophical Transactions of the Royal Society of London B: Biological Sciences, 364, 399-407.
33. Levi, D. M., & Li, R. W. (2009b). Perceptual learning as a potential treatment for amblyopia: A mini-review. Vision Research, 49, 2535-2549.
34. Levi, D. M., & Polat, U. (1996). Neural plasticity in adults with amblyopia. Proceedings of the National Academy of Science United States of America, 93, 6830-6834.
35. Levi, D. M., Polat, U., & Hu, Y. S. (1997). Improvement in Vernier acuity in adults with amblyopia. Practice makes better. Investigative Ophthalmology and Vision Science, 38, 1493-1510.
36. Levitt, H. (1971). Transformed up-down methods in psychoacoustics. Journal of Acoustic Society of America, 49, 467.
37. Li, R. W., Klein, S. A., & Levi, D. M. (2008). Prolonged perceptual learning of positional acuity in adult amblyopia: Perceptual template retuning dynamics. Journal of Neuroscience, 28, 14223-14229.
38. Li, R. W., & Levi, D. M. (2004). Characterizing the mechanisms of improvement for position discrimination in adult amblyopia. Journal of Vision, 4(6):7, 476-487, http://journalofvision.org/4/6/7/, doi:10.1167/4.6.7.
39. Li, R. W., Provost, A., & Levi, D. M. (2007). Extended perceptual learning results in substantial recovery of positional acuity and visual acuity in juvenile amblyopia. Investigative Ophthalmology and Vision Science, 48, 5046-5051.
40. Li, R. W., Young, K. G., Hoenig, P., & Levi, D. M. (2005). Perceptual learning improves visual performance in juvenile amblyopia. Investigative Ophthalmology and Vision Science, 46, 3161-3168.
41. Li, X., Lu, Z. L., Xu, P., Jin, J., & Zhou, Y. (2003). Generating high gray-level resolution monochrome displays with conventional computer graphics cards and color monitors. Journal of Neuroscience Methods, 130, 9-18.
42. Lu, Z.-L., Chu, W., & Dosher, B. A. (2006). Perceptual Learning of motion direction discrimination in fovea: Separable mechanisms, Vision Research, 46, 2315-2327.
43. Lu, Z.-L., & Dosher, B. A. (1998). External noise distinguishes attention mechanisms. Vision Research, 38, 1183-1198.
44. Lu, Z.-L.,&Dosher, B. A. (2009).Mechanisms of perceptual learning. Learning and Perception, 1, 19-36.
45. Lu, Z. L., & Dosher, B. A. (1999). Characterizing human perceptual inefficiencies with equivalent internal noise. Journal of the Optical Society of America A, Optics, Image Science, and Vision, 16, 764-778.
46. Lu, Z. L., & Dosher, B. A. (2008). Characterizing observer states using external noise and observer models: Assessing internal representations with external noise. Psychological Review, 115, 44-82.
47. Lu, Z. L., Liu J., & Dosher B. A. (in press). Modeling mechanisms of perceptual learning with augmented Hebbian re-weighting. Vision Research.
48. McKee, S. P., Levi, D. M., & Movshon, J. A. (2003). The pattern of visual deficits in amblyopia. Journal of Vision, 3(5):5, 380-405, http://journalofvision.org/3/5/5/, doi:10.1167/3.5.5.
49. Mehdorn, E., Mattheus, S., Schuppe, A., Klein, U., & Kommerell, G. (1981). Treatment for amblyopia with rotating gratings and subsequent occlusion: A controlled study. International Ophthalmology, 3, 161-166.
50. Mou, T. (1966). Logarithmic visual acuity chart and fivescore recording. Chinese Journal of Ophthalmology, 13, 96-106.
51. Movshon, J. A., Eggers, H. M., Gizzi, M. S., Hendrickson, A. E., Kiorpes, L., & Boothe, R. G. (1987). Effects of early unilateral blur on the macaque's visual system. III: Physiological observations. Journal of Neuroscience, 7, 1340-1351.
52. Nordmann, J. P., Freeman, R. D., & Casanova, C. (1992). Contrast sensitivity in amblyopia: Masking effects of noise. Investigative Ophthalmology & Vision Science, 33, 2975-2985.
53. Pelli, D. G. (1997). The VideoToolbox software for visual psychophysics: Transforming numbers into movies. Spatial Vision, 10, 437-442.
54. Pelli, D. G., & Farell, B. (1999). Why use noise? Journal of the Optical Society of America A, Optics, Image, Science, and Vision, 16, 647-653.
55. Pelli, D. G., Levi, D. M., & Chung, S. T. (2004). Using visual noise to characterize amblyopic letter identification. Journal of Vision, 4(10):6, 904-920, http://journalofvision.org/4/10/6/, doi:10.1167/4.10.6.
56. Polat, U. (1999). Functional architecture of long-range perceptual interactions. Spatial Vision, 12, 143-162.
57. Polat, U. (2008). Restoration of underdeveloped cortical functions: Evidence from treatment of adult amblyopia. Restorative Neurology and Neuroscience, 26, 413-424.
58. Polat, U. (2009). Making perceptual learning practical to improve visual functions. Vision Research, 49, 2566-2573.
59. Polat, U., Ma-Naim, T., Belkin, M., & Sagi, D. (2004). Improving vision in adult amblyopia by perceptual learning. Proceedings of the National Academy of Sciences of the United States of America, 101, 6692-6697.
60. Polat, U., Sagi, D., & Norcia, A. M. (1997). Abnormal long-range spatial interactions in amblyopia. Vision Research, 37, 737-744.
61. Schor, C., & Wick, B. (1983). Rotating grating treatment of amblyopia with and without eccentric fixation. Journal of American Optometric Association, 54, 545-549.
62. Sharma, V., Levi, D. M., & Klein, S. A. (2000). Undercounting features and missing features: Evidence for a high-level deficit in strabismic amblyopia. Nature Neuroscience, 3, 496-501.
63. Simmers, A. J., & Gray, L. S. (1999). Improvement of visual function in an adult amblyope. Optometry and Vision Science, 76, 82-87.
64. Simmers, A. J., Ledgeway, T., Hess, R. F., & McGraw, P. V. (2003). Deficits to global motion processing in human amblyopia. Vision Research, 43, 729-738.
65. Terrell, A. (1981). Cambridge stimulator treatment for amblyopia. An evaluation of 80 consecutive cases treated by this method. Australian Journal of Ophthalmology, 9, 121-127.
66. Wick, B., Wingard, M., Cotter, S., & Scheiman, M. (1992). Anisometropic amblyopia: Is the patient ever too old to treat? Optometry and Vision Science, 69, 866-878.
67. Wong, E. H., Levi, D. M., & McGraw, P. V. (2005). Spatial interactions reveal inhibitory cortical networks in human amblyopia. Vision Research, 45, 2810-2819.
68. Xu, P., Lu, Z. L., Qiu, Z., & Zhou, Y. (2006). Identify mechanisms of amblyopia in Gabor orientation identification with external noise. Vision Research, 46, 3748-3760.
69. Zhou, Y. F., Huang, C. B., Xu, P. J., Tao, L. M., Qiu, Z. P., Li, X. R., et al. (2006). Perceptual learning improves contrast sensitivity and visual acuity in adults with anisometropic amblyopia. Vision Research, 46, 739-750.