Controlling the number of tooth rows

Science Signaling

Volumn 2, Issue 85, 2009, Pages

  Mikkola, Marja L ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR OSR2; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; MSX1 PROTEIN, MOUSE; OSR2 PROTEIN, MOUSE; SHH PROTEIN, MOUSE; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR PITX2;

BRANCHING MORPHOGENESIS; DENTITION; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE FUNCTION; HUMAN; MAMMALIAN GENETICS; NONHUMAN; PRIORITY JOURNAL; REVIEW; TOOTH DEVELOPMENT; TOOTH MALFORMATION; ANIMAL; ECTODERM; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; MAMMAL; MESODERM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; PRENATAL DEVELOPMENT; REGENERATION; SPECIES DIFFERENCE; VERTEBRATE;

MAMMALIA; VERTEBRATA;

ANIMALS; BONE MORPHOGENETIC PROTEIN 4; DENTITION; ECTODERM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; MAMMALS; MESODERM; MICE; MICE, KNOCKOUT; MSX1 TRANSCRIPTION FACTOR; ODONTOGENESIS; REGENERATION; SPECIES SPECIFICITY; TOOTH, SUPERNUMERARY; TRANSCRIPTION FACTORS; VERTEBRATES;

EID: 70449698513     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.285pe53     Document Type: Review

References (36)

1. M. M. Smith, Vertebrate dentitions at the origin of jaws: When and how pattern evolved. Evol. Dev. 5, 394-413 (2003).
2. G. J. Fraser, R. F. Bloomquist, J. T. Streelman, A periodic pattern generator for dental diversity. BMC Biol. 6, 32 (2008).
3. M. Buchtová, G. R. Handrigan, A. S. Tucker, S. Lozanoff, L. Town, K. Fu, V. M. Diewert, C. Wicking, J. M. Richman, Initiation and patterning of the snake dentition are dependent on Sonic hedgehog signaling. Dev. Biol. 319, 132-145 (2008).
4. M. L. Mikkola, Genetic basis of skin appendage development. Semin. Cell Dev. Biol. 18, 225-236 (2007).
5. G. J. Fraser, A. Graham, M. M. Smith, Developmental and evolutionary origins of the vertebrate dentition: Molecular controls for spatio-temporal organisation of tooth sites in osteichthyans. J. Exp. Zoolog. B Mol. Dev. Evol. 306, 183-203 (2006).
6. M. M. Smith, G. J. Fraser, N. Chaplin, C. Hobbs, A. Graham, Reiterative pattern of sonic hedgehog expression in the catshark dentition reveals a phylogenetic template for jawed vertebrates. Proc. Biol. Sci. 276, 1225-1233 (2009).
7. T. X. Jiang, R. B. Widelitz, W. M. Shen, P. Will, D. Y. Wu, C. M. Lin, H. S. Jung, C. M. Chuong, Integument pattern formation involves genetic and epigenetic controls: Feather arrays simulated by digital hormone models. Int. J. Dev. Biol. 48, 117-135 (2004).
8. I. Salazar-Ciudad, J. Jernvall, A gene network model accounting for development and evolution of mammalian teeth. Proc. Natl. Acad. Sci. U.S.A. 99, 8116-8120 (2002).
9. K. D. Kavanagh, A. R. Evans, J. Jernvall, Predicting evolutionary patterns of mammalian teeth from development. Nature 449, 427-432 (2007).
10. Z. Zhang, Y. Lan, Y. Chai, R. Jiang, Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row. Science 323, 1232-1234 (2009).
11. T. Mustonen, J. Pispa, M. L. Mikkola, M. Pummila, A. T. Kangas, L. Pakkasjärvi, R. Jaatinen, I. Thesleff, Stimulation of ectodermal organ development by Ectodysplasin-A1. Dev. Biol. 259, 123-136 (2003).
12. Q. Zhang, N. S. Murcia, L. R. Chittenden, W. G. Richards, E. J. Michaud, R. P. Woychik, B. K. Yoder, Loss of the Tg737 protein results in skeletal patterning defects. Dev. Dyn. 227, 78-90 (2003).
13. Y. Kassai, P. Munne, Y. Hotta, E. Penttilä, K. Kavanagh, N. Ohbayashi, S. Takada, I. Thesleff, J. Jernvall, N. Itoh, Regulation of mammalian tooth cusp patterning by ectodin. Science 309, 2067-2070 (2005).
14. O. D. Klein, G. Minowada, R. Peterkova, A. Kangas, B. D. Yu, H. Lesot, M. Peterka, J. Jernvall, G. R. Martin, Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial- mesenchymal FGF signaling. Dev. Cell 11, 181-190 (2006).
15. J. Jernvall, I. Thesleff, Reiterative signaling and patterning during mammalian tooth morphogenesis. Mech. Dev. 92, 19-29 (2000).
16. M. Mina, E. J. Kollar, The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium. Arch. Oral Biol. 32, 123-127 (1987).
17. A. G. Lumsden, Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ. Development 103, (Suppl), 155-169 (1988).
18. I. Thesleff, M. Tummers, Tooth organogenesis and regeneration (January 31, 2009). StemBook, ed. The Stem Cell Research Community, StemBook, 10.3824/stembook.1.37.1, www.stembook.org.
19. S. Vainio, I. Karavanova, A. Jowett, I. Thesleff, Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 75, 45-58 (1993).
20. Y. Chen, M. Bei, I. Woo, I. Satokata, R. Maas, Msx1 controls inductive signaling in mammalian tooth morphogenesis. Development 122, 3035-3044 (1996).
21. M. Bei, R. Maas, FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development. Development 125, 4325-4333 (1998).
22. M. Bei, K. Kratochwil, R. L. Maas, BMP4 rescues a non-cell-autonomous function of Msx1 in tooth development. Development 127, 4711-4718 (2000).
23. E. Järvinen, I. Salazar-Ciudad, W. Birchmeier, M. M. Taketo, J. Jernvall, I. Thesleff, Continuous tooth generation in mouse is induced by activated epithelial Wnt/b-catenin signaling. Proc. Natl. Acad. Sci. U.S.A. 103, 18627-18632 (2006).
24. F. Liu, E. Y. Chu, B.Watt, Y. Zhang, N. M. Gallant, T. Andl, S. H. Yang, M. M. Lu, S. Piccolo, R. Schmidt-Ullrich, M. M. Taketo, E. E. Morrisey, R. Atit, A. A. Dlugosz, S. E. Millar, Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev. Biol. 313, 210-224 (2008).
25. W. P. Luckett, An ontogenetic assessment of dental homologies in therian mammals. In Mammal Phylogeny: Mesozoic Differentiation, Multituberculates, Monotremes, Early Therians, and Marsupials, F. S. Szalay, M. J. Novacek, M. C. Kenna, Eds. (Springer, New York, 1993), pp. 182-204.
26. E. Järvinen, M. Tummers, I. Thesleff, The role of the dental lamina in mammalian tooth replacement. J. Exp. Zoolog. B (Mol. Dev. Evol.) 312B, 281-291 (2009).
27. X. Zhao, Z. Zhang, Y. Song, X. Zhang, Y. Zhang, Y. Hu, S. H. Fromm, Y. Chen, Transgenically ectopic expression of Bmp4 to the Msx1 mutant dental mesenchyme restores downstream gene expression but represses Shh and Bmp2 in the enamel knot of wild type tooth germ. Mech. Dev. 99, 29-38 (2000).
28. A. MacKenzie, M. W. Ferguson, P. T. Sharpe, Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape. Development 115, 403-420 (1992).
29. J. Laurikkala, Y. Kassai, L. Pakkasjärvi, I. Thesleff I, N. Itoh, Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. Dev. Biol. 264, 91-105 (2003).
30. W. Liu, J. Selever, D. Murali, X. Sun, S. M. Brugger, L. Ma, R. J. Schwartz, R. Maxson, Y. Furuta, J. F. Martin, Threshold-specific requirements for Bmp4 in mandibular development. Dev. Biol. 283, 282-293 (2005).
31. A. G. Lumsden, Pattern formation in the molar dentition of the mouse. J. Biol. Buccale 7, 77-103 (1979).
32. M. V. Plikus, M. Zeichner-David, J. A. Mayer, J. Reyna, P. Bringas, J. G. Thewissen, M. L. Snead, Y. Chai, C. M. Chuong, Morphoregulation of teeth: Modulating the number, size, shape and differentiation by tuning Bmp activity. Evol. Dev. 7, 440-457 (2005).
33. S. B. Wise, D. W. Stock, Conservation and divergence of Bmp2a, Bmp2b, and Bmp4 expression patterns within and between dentitions of teleost fishes. Evol. Dev. 8, 511-523 (2006).
34. P. M. Munne, M. Tummers, E. Järvinen, I. Thesleff, J. Jernvall, Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth induction. Development 136, 393-402 (2009).
35. M. Tummers, I. Thesleff, The importance of signal pathway modulation in all aspects of tooth development. J. Exp. Zoolog. B (Mol. Dev. Evol.) 312B, 309-319 (2009).
36. I thank I. Thesleff for discussions and I. T. and J. Jernvall for critical reading of the manuscript. G. Fraser, K. Hurmerinta, and M. Jussila provided illustrations.