Structure and ligand-based drug design to propose novel α-glucosidase inhibitors

Current Bioactive Compounds

Volumn 5, Issue 2, 2009, Pages 99-109

  Gomes, Adriane Da S ^a   Silva, Carlos H T P ^a   Da Silva, Vinicius B ^a   Carvalho, Ivone ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

glucosidase; Glucosidase inhibitor; Ligand based drug design; Structure based drug design

Indexed keywords

1 DEOXYNOJIRIMYCIN; 2,4,5 TRIHYDROXY CYCLOHEXANONE; 4 O ALPHA DEXTRO GLUCOPYRANOSYLMORANOLINE; ADENOPHORINE; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDASE INHIBITOR; ALPHA HOMONOJIRIMYCIN; AMINOSUGAR; BETA GLUCOSIDASE; BETA HOMONOJIRIMYCIN; CARBASUGAR; ENZYME INHIBITOR; GLYCOSIDASE INHIBITOR; HYDROLASE INHIBITOR; MALTOSE; MDL 73945; METHYL 3 (1' AMINO 5' METHYLCYCLOHEXANE 2',3',4' TRIHYDROXY) 2,4,6 TRIHYDROXY 3 DESOXY ALPHA DEXTRO GLUCOPYRANOSIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENETIC ALGORITHM; GLYCOPROTEIN SYNTHESIS; HUMAN; IC 50; MOLECULAR INTERACTION; NONHUMAN; PHARMACOPHORE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; STRUCTURE ACTIVITY RELATION;

EID: 70449698476     PISSN: 15734072     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340709788451984     Document Type: Article

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