Effect of ethacrynic acid on the anticonvulsant activity of the second-generation antiepileptics against maximal electroshock-induced seizures in mice

Epilepsy Research

Volumn 87, Issue 2-3, 2009, Pages 190-196

  Łukawski, Krzysztof ^a   Świderska, Grazyna ^a   Czuczwar, Stanisław J ^a,b  

^a INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Antiepileptics; Drug interactions; Ethacrynic acid; Maximal electroshock seizure test; Mice

Indexed keywords

ETACRYNIC ACID; LAMOTRIGINE; OXCARBAZEPINE; TOPIRAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG COMPETITION; DRUG DOSE REGIMEN; DRUG POTENTIATION; ELECTRIC SHOCK; MALE; MONOTHERAPY; MOUSE; NEUROPROTECTION; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; SEIZURE; SINGLE DRUG DOSE;

ANALYSIS OF VARIANCE; ANIMALS; ANTICONVULSANTS; AVOIDANCE LEARNING; BRAIN; BRAIN CHEMISTRY; CARBAMAZEPINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; ELECTROSHOCK; ETHACRYNIC ACID; FRUCTOSE; MALE; MICE; MOTOR SKILLS; SEIZURES; STATISTICS, NONPARAMETRIC; TRIAZINES;

EID: 70449670356     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2009.08.016     Document Type: Article

References (30)

1. Barbaro N.M., Takahashi D.K., and Baraban S.C. A potential role for astrocytes in mediating the antiepileptic actions of furosemide in vitro. Neuroscience 128 (2004) 655-663
2. Boissier J.R., Tardy J., and Diverres J.C. Une nouvelle methode simple pour explorer l'action 'tranquilisante': le test de la cheminee. Med. Exp. (Basel) 3 (1960) 81-84
3. Brater D.C. Pharmacology of diuretics. Am. J. Med. Sci. 319 (2000) 38-50
4. Cooling M.J., and Sim M.F. An investigation of the sex difference in the diuretic response to ethacrynic acid in mice. Br. J. Pharmacol. 61 (1977) 569-572
5. Dodgson S.J., Shank R.P., and Maryanoff B.E. Topiramate as an inhibitor of carbonic anhydrase isoenzymes. Epilepsia 41 Suppl. 1 (2000) S35-S39
6. Fisher R.S., Pedley T.A., Moody Jr. W.J., and Prince D.A. The role of extracellular potassium in hippocampal epilepsy. Arch. Neurol. 33 (1976) 76-83
7. Foy J.M., and Furman B.L. Effect of diuretics on mouse blood sugar following single dose administration. Br. J. Pharmacol. 41 (1971) 287-297
8. Gibbs J.W., Sombati S., DeLorenzo R.J., and Coulter D.A. Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia 41 Suppl 1 (2000) S10-S16
9. Gillen C.M., Brill S., Payne J.A., and Forbush III B. Molecular cloning and functional expression of the K-Cl cotransport from rabbit, rat, and human: a new member of the cation-chloride cotransporter family. J. Biol. Chem. 271 (1996) 16237-16244
10. A-mediated responses and activation of a potassium conductance. Neuropharmacology 42 (2002) 210-220
11. Hesdorffer D.C., Stables J.P., Hauser W.A., Annegers J.F., and Cascino G. Are certain diuretics also anticonvulsants?. Ann. Neurol. 50 (2001) 458-462
12. Holtkamp M., Matzen J., Buchheim K., Walker M.C., and Meierkord H. Furosemide terminates limbic status epilepticus in freely moving rats. Epilepsia 44 (2003) 1141-1144
13. Huh K., Lee S.I., and Song J.W. Protective effect of diallyl disulfide on ethacrynic acid-induced toxicity in mice. Arch. Pharm. Res. 10 (1987) 149-152
14. Inoue M., Uriu T., Otani H., Hara M., Omori K., and Inagaki C. Intracerebroventricular injection of ethacrynic acid induces status epilepticus. Eur. J. Pharmacol. 166 (1989) 101-106
15. Litchfield J.T., and Wilcoxon F. A simplified method of evaluating dose-effect experiments. J. Pharmacol. Exp. Ther. 96 (1949) 99-113
16. Löscher W., Fassbender C.P., and Nolting B. The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models. Epilepsy Res. 8 (1991) 79-94
17. Luszczki J.J., Borowicz K.K., Swiader M., and Czuczwar S.J. Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis. Epilepsia 44 (2003) 489-499
18. Luszczki J.J., and Czuczwar S.J. How significant is the difference between drug doses influencing the threshold for electroconvulsions?. Pharmacol. Rep. 57 (2005) 782-786
19. Luszczki J.J., Sawicka K.M., Kozinska J., Borowicz K.K., and Czuczwar S.J. Furosemide potentiates the anticonvulsant action of valproate in the mouse maximal electroshock seizure model. Epilepsy Res. 76 (2007) 66-72
20. Margineanu D.G., and Klitgaard H. Differential effects of cation-chloride co-transport-blocking diuretics in a rat hippocampal slice model of epilepsy. Epilepsy Res. 69 (2006) 93-99
21. o regulation. Am. J. Physiol. 273 (1997) C1516-C1525
22. Payne J.A., Rivera C., Voipio J., and Kaila K. Cation-chloride co-transporters in neuronal communication, development and trauma. Trends Neurosci. 26 (2003) 199-206
23. Payne J.A., Stevenson T.J., and Donaldson L.F. Molecular characterization of a putative K-Cl cotransporter in rat brain: a neuronal-specific isoform. J. Biol. Chem. 271 (1996) 16245-16252
24. Reid K.H., Guo S.Z., and Iyer V.G. Agents which block potassium-chloride cotransport prevent sound-triggered seizures in post-ischemic audiogenic seizure-prone rats. Brain Res. 864 (2000) 134-137
25. Reid K.H., Li G.-Y., Payne R.S., Schurr A., and Cooper N.G.F. The mRNA level of the potassium-chloride cotransporter KCC2 covaries with seizure susceptibility in inferior colliculus of the post-ischemic audiogenic seizure-prone rat. Neurosci. Lett. 308 (2001) 29-32
26. + current fractions by the new anticonvulsant topiramate. J. Pharmacol. Exp. Ther. 288 (1999) 960-968
27. Venault P., Chapouthier G., Prado de Carvalho L., Simiand J., Morre M., Dodd R.H., and Rossier J. Benzodiazepine impairs and β-carboline enhances performance in learning and memory tasks. Nature 321 (1986) 864-866
28. White H.S., Brown S.D., Woodhead J.H., Skeen G.A., and Wolf H.H. Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism. Epilepsia 41 Suppl. 1 (2000) S17-S20
29. Zhang X., Velumian A.A., Jones O.T., and Carlen P.L. Modulation of high voltage activated calcium channels in dentate granule cells by topiramate. Epilepsia 41 Suppl. 1 (2000) S52-S60
30. Zona C., Tancredi V., Longone P., D'Arcangelo G., D'Antuono M., Manfredi M., and Avoli M. Neocortical potassium currents are enhanced by the antiepileptic drug lamotrigine. Epilepsia 43 (2002) 685-690