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Volumn 217, Issue 1-2, 2009, Pages 46-50

Polyclonal immunoglobulins (IVIg) induce expression of MMP-9 in microglia

Author keywords

Intravenous immunoglobulins; IVIg; Matrix metalloproteinase; Microglia; MMP 9

Indexed keywords

GELATINASE A; GELATINASE B; IMMUNOGLOBULIN 7S; IMMUNOGLOBULIN F(AB) FRAGMENT; LIPOPOLYSACCHARIDE; MACROPHAGE ELASTASE; MATRILYSIN; STROMELYSIN; STROMELYSIN 2; STROMELYSIN 3; UNCLASSIFIED DRUG; VENIMMUN N;

EID: 70449658833     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.09.016     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 33645869560 scopus 로고    scopus 로고
    • Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis
    • Agrawal S., Anderson P., Durbeej M., van Rooijen N., Ivars F., Opdenakker G., and Sorokin L.M. Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis. J. Exp. Med. 4 (2006) 1007-1019
    • (2006) J. Exp. Med. , vol.4 , pp. 1007-1019
    • Agrawal, S.1    Anderson, P.2    Durbeej, M.3    van Rooijen, N.4    Ivars, F.5    Opdenakker, G.6    Sorokin, L.M.7
  • 2
    • 0036842362 scopus 로고    scopus 로고
    • Preanalytical aspects regarding the measurement of metalloproteinase-9 and tissue inhibitor or metalloproteinase-1 in blood
    • Alby C., Ben Abdesselam O., Foglietti M.J., and Beaudeux J.L. Preanalytical aspects regarding the measurement of metalloproteinase-9 and tissue inhibitor or metalloproteinase-1 in blood. Clin. Chim. Acta 1-2 (2002) 183-186
    • (2002) Clin. Chim. Acta , vol.1-2 , pp. 183-186
    • Alby, C.1    Ben Abdesselam, O.2    Foglietti, M.J.3    Beaudeux, J.L.4
  • 5
    • 0031794031 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression in rat pancreatic islets
    • Barro C., Zaoui P., Morel F., and Benhamou P.Y. Matrix metalloproteinase expression in rat pancreatic islets. Pancreas 4 (1998) 378-382
    • (1998) Pancreas , vol.4 , pp. 378-382
    • Barro, C.1    Zaoui, P.2    Morel, F.3    Benhamou, P.Y.4
  • 9
    • 0029907622 scopus 로고    scopus 로고
    • The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution
    • Cuzner M.L., Gveric D., Strand C., Loughlin A.J., Paemen L., Opdenakker G., and Newcombe J. The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution. J. Neuropathol. Exp. Neurol. 12 (1996) 1194-1204
    • (1996) J. Neuropathol. Exp. Neurol. , vol.12 , pp. 1194-1204
    • Cuzner, M.L.1    Gveric, D.2    Strand, C.3    Loughlin, A.J.4    Paemen, L.5    Opdenakker, G.6    Newcombe, J.7
  • 10
    • 33847202635 scopus 로고    scopus 로고
    • The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies
    • Dehmel T., Janke A., Hartung H.P., Goebel H.H., Wiendl H., and Kieseier B.C. The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies. Neurobiol. Dis. 3 (2007) 665-674
    • (2007) Neurobiol. Dis. , vol.3 , pp. 665-674
    • Dehmel, T.1    Janke, A.2    Hartung, H.P.3    Goebel, H.H.4    Wiendl, H.5    Kieseier, B.C.6
  • 12
    • 7744231499 scopus 로고    scopus 로고
    • MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity
    • Esparza J., Kruse M., Lee J., Michaud M., and Madri J.A. MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity. FASEB J. 14 (2004) 1682-1691
    • (2004) FASEB J. , vol.14 , pp. 1682-1691
    • Esparza, J.1    Kruse, M.2    Lee, J.3    Michaud, M.4    Madri, J.A.5
  • 13
    • 33845749224 scopus 로고    scopus 로고
    • Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma
    • Gerlach R.F., Demacq C., Jung K., and Tanus-Santos J.E. Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma. Clin. Biochem. 1-2 (2007) 119-123
    • (2007) Clin. Biochem. , vol.1-2 , pp. 119-123
    • Gerlach, R.F.1    Demacq, C.2    Jung, K.3    Tanus-Santos, J.E.4
  • 14
    • 0027368518 scopus 로고
    • Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein
    • Gijbels K., Proost P., Masure S., Carton H., Billiau A., and Opdenakker G. Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein. J. Neurosci. Res. 4 (1993) 432-440
    • (1993) J. Neurosci. Res. , vol.4 , pp. 432-440
    • Gijbels, K.1    Proost, P.2    Masure, S.3    Carton, H.4    Billiau, A.5    Opdenakker, G.6
  • 15
    • 0022922108 scopus 로고
    • Characterization of ameboid microglia isolated from developing mammalian brain
    • Giulian D., and Baker T.J. Characterization of ameboid microglia isolated from developing mammalian brain. J. Neurosci. 8 (1986) 2163-2178
    • (1986) J. Neurosci. , vol.8 , pp. 2163-2178
    • Giulian, D.1    Baker, T.J.2
  • 16
    • 0030451627 scopus 로고    scopus 로고
    • beta-Amyloid induction of gelatinase B secretion in cultured microglia: inhibition by dexamethasone and indomethacin
    • Gottschall P.E. beta-Amyloid induction of gelatinase B secretion in cultured microglia: inhibition by dexamethasone and indomethacin. NeuroReport 18 (1996) 3077-3080
    • (1996) NeuroReport , vol.18 , pp. 3077-3080
    • Gottschall, P.E.1
  • 17
    • 0029829594 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons
    • Gottschall P.E., and Deb S. Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons. Neuroimmunomodulation. 2-3 (1996) 69-75
    • (1996) Neuroimmunomodulation. , vol.2-3 , pp. 69-75
    • Gottschall, P.E.1    Deb, S.2
  • 18
    • 0028834682 scopus 로고
    • Increased production of gelatinase B (matrix metalloproteinase-9) and interleukin-6 by activated rat microglia in culture
    • Gottschall P.E., Yu X., and Bing B. Increased production of gelatinase B (matrix metalloproteinase-9) and interleukin-6 by activated rat microglia in culture. J. Neurosci. Res. 3 (1995) 335-342
    • (1995) J. Neurosci. Res. , vol.3 , pp. 335-342
    • Gottschall, P.E.1    Yu, X.2    Bing, B.3
  • 19
    • 0034710362 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system
    • Hartung H.P., and Kieseier B.C. The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system. J. Neuroimmunol. 2 (2000) 140-147
    • (2000) J. Neuroimmunol. , vol.2 , pp. 140-147
    • Hartung, H.P.1    Kieseier, B.C.2
  • 20
    • 20444408392 scopus 로고    scopus 로고
    • Intravenous immunoglobulin treatment of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis
    • Humle J.S., and Sorensen P.S. Intravenous immunoglobulin treatment of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. J. Neurol. Sci. 1-2 (2005) 61-65
    • (2005) J. Neurol. Sci. , vol.1-2 , pp. 61-65
    • Humle, J.S.1    Sorensen, P.S.2
  • 21
    • 33746788072 scopus 로고    scopus 로고
    • Serum levels of matrix metalloproteinases-2 and -9 and their tissue inhibitors in inflammatory neuromuscular disorders
    • Hurnaus S., Mueller-Felber W., Pongratz D., and Schoser B.G. Serum levels of matrix metalloproteinases-2 and -9 and their tissue inhibitors in inflammatory neuromuscular disorders. Eur. Neurol. 4 (2006) 204-208
    • (2006) Eur. Neurol. , vol.4 , pp. 204-208
    • Hurnaus, S.1    Mueller-Felber, W.2    Pongratz, D.3    Schoser, B.G.4
  • 23
    • 34147109292 scopus 로고    scopus 로고
    • IVIG enters the central nervous system during treatment of experimental autoimmune encephalomyelitis and is localised to inflammatory lesions
    • Jorgensen S.H., Storm N., Jensen P.E., Laursen H., and Sorensen P.S. IVIG enters the central nervous system during treatment of experimental autoimmune encephalomyelitis and is localised to inflammatory lesions. Exp. Brain Res. 4 (2007) 462-469
    • (2007) Exp. Brain Res. , vol.4 , pp. 462-469
    • Jorgensen, S.H.1    Storm, N.2    Jensen, P.E.3    Laursen, H.4    Sorensen, P.S.5
  • 24
    • 0035162094 scopus 로고    scopus 로고
    • Blood specimen collection methods influence the concentration and the diagnostic validity of matrix metalloproteinase 9 in blood
    • Jung K., Lein M., Laube C., and Lichtinghagen R. Blood specimen collection methods influence the concentration and the diagnostic validity of matrix metalloproteinase 9 in blood. Clin. Chim. Acta 1-2 (2001) 241-244
    • (2001) Clin. Chim. Acta , vol.1-2 , pp. 241-244
    • Jung, K.1    Lein, M.2    Laube, C.3    Lichtinghagen, R.4
  • 25
    • 0037080365 scopus 로고    scopus 로고
    • Differential regulation of myelin phagocytosis by macrophages/microglia, involvement of target myelin, Fc receptors and activation by intravenous immunoglobulins
    • Kuhlmann T., Wendling U., Nolte C., Zipp F., Maruschak B., Stadelmann C., Siebert H., and Bruck W. Differential regulation of myelin phagocytosis by macrophages/microglia, involvement of target myelin, Fc receptors and activation by intravenous immunoglobulins. J. Neurosci. Res. 2 (2002) 185-190
    • (2002) J. Neurosci. Res. , vol.2 , pp. 185-190
    • Kuhlmann, T.1    Wendling, U.2    Nolte, C.3    Zipp, F.4    Maruschak, B.5    Stadelmann, C.6    Siebert, H.7    Bruck, W.8
  • 26
    • 4444262381 scopus 로고    scopus 로고
    • The expression of matrix metalloproteinase-12 by oligodendrocytes regulates their maturation and morphological differentiation
    • Larsen P.H., and Yong V.W. The expression of matrix metalloproteinase-12 by oligodendrocytes regulates their maturation and morphological differentiation. J. Neurosci. 35 (2004) 7597-7603
    • (2004) J. Neurosci. , vol.35 , pp. 7597-7603
    • Larsen, P.H.1    Yong, V.W.2
  • 27
    • 0346749451 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan
    • Larsen P.H., Wells J.E., Stallcup W.B., Opdenakker G., and Yong V.W. Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan. J. Neurosci. 35 (2003) 11127-11135
    • (2003) J. Neurosci. , vol.35 , pp. 11127-11135
    • Larsen, P.H.1    Wells, J.E.2    Stallcup, W.B.3    Opdenakker, G.4    Yong, V.W.5
  • 28
    • 33645643179 scopus 로고    scopus 로고
    • Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice
    • Larsen P.H., DaSilva A.G., Conant K., and Yong V.W. Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice. J. Neurosci. 8 (2006) 2207-2214
    • (2006) J. Neurosci. , vol.8 , pp. 2207-2214
    • Larsen, P.H.1    DaSilva, A.G.2    Conant, K.3    Yong, V.W.4
  • 29
    • 34249734136 scopus 로고    scopus 로고
    • New concepts on progressive multiple sclerosis
    • Lassmann H. New concepts on progressive multiple sclerosis. Curr. Neurol. Neurosci. Rep. 3 (2007) 239-244
    • (2007) Curr. Neurol. Neurosci. Rep. , vol.3 , pp. 239-244
    • Lassmann, H.1
  • 30
    • 0030483220 scopus 로고    scopus 로고
    • Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis
    • Leppert D., Waubant E., Burk M.R., Oksenberg J.R., and Hauser S.L. Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis. Ann. Neurol. 6 (1996) 846-852
    • (1996) Ann. Neurol. , vol.6 , pp. 846-852
    • Leppert, D.1    Waubant, E.2    Burk, M.R.3    Oksenberg, J.R.4    Hauser, S.L.5
  • 32
    • 3042694846 scopus 로고    scopus 로고
    • Interferon-beta inhibits the expression of metalloproteinases in rat glial cell cultures: implications for multiple sclerosis pathogenesis and treatment
    • Liuzzi G.M., Latronico T., Fasano A., Carlone G., and Riccio P. Interferon-beta inhibits the expression of metalloproteinases in rat glial cell cultures: implications for multiple sclerosis pathogenesis and treatment. Mult. Scler. 3 (2004) 290-297
    • (2004) Mult. Scler. , vol.3 , pp. 290-297
    • Liuzzi, G.M.1    Latronico, T.2    Fasano, A.3    Carlone, G.4    Riccio, P.5
  • 33
    • 35848933695 scopus 로고    scopus 로고
    • Inhibitory effect of polyunsaturated fatty acids on MMP-9 release from microglial cells-implications for complementary multiple sclerosis treatment
    • Liuzzi G.M., Latronico T., Rossano R., Viggiani S., Fasano A., and Riccio P. Inhibitory effect of polyunsaturated fatty acids on MMP-9 release from microglial cells-implications for complementary multiple sclerosis treatment. Neurochem. Res. 12 (2007) 2184-2193
    • (2007) Neurochem. Res. , vol.12 , pp. 2184-2193
    • Liuzzi, G.M.1    Latronico, T.2    Rossano, R.3    Viggiani, S.4    Fasano, A.5    Riccio, P.6
  • 34
    • 38349129173 scopus 로고    scopus 로고
    • Differences in both matrix metalloproteinase 9 concentration and zymographic profile between plasma and serum with clot activators are due to the presence of amorphous silica or silicate salts in blood collection devices
    • Mannello F., Tanus-Santos J.E., Meschiari C.A., and Tonti G.A. Differences in both matrix metalloproteinase 9 concentration and zymographic profile between plasma and serum with clot activators are due to the presence of amorphous silica or silicate salts in blood collection devices. Anal. Biochem. 1 (2008) 56-63
    • (2008) Anal. Biochem. , vol.1 , pp. 56-63
    • Mannello, F.1    Tanus-Santos, J.E.2    Meschiari, C.A.3    Tonti, G.A.4
  • 35
    • 2642577574 scopus 로고    scopus 로고
    • Effect of a short-term in vitro exposure to the marine toxin domoic acid on viability, tumor necrosis factor-alpha, matrix metalloproteinase-9 and superoxide anion release by rat neonatal microglia
    • Mayer A.M., Hall M., Fay M.J., Lamar P., Pearson C., Prozialeck W.C., Lehmann V.K., Jacobson P.B., Romanic A.M., Uz T., and Manev H. Effect of a short-term in vitro exposure to the marine toxin domoic acid on viability, tumor necrosis factor-alpha, matrix metalloproteinase-9 and superoxide anion release by rat neonatal microglia. BMC. Pharmacol. 7 (2001)
    • (2001) BMC. Pharmacol. , vol.7
    • Mayer, A.M.1    Hall, M.2    Fay, M.J.3    Lamar, P.4    Pearson, C.5    Prozialeck, W.C.6    Lehmann, V.K.7    Jacobson, P.B.8    Romanic, A.M.9    Uz, T.10    Manev, H.11
  • 36
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn F., and Ravetch J.V. Fcgamma receptors as regulators of immune responses. Nat. Rev. Immunol. 1 (2008) 34-47
    • (2008) Nat. Rev. Immunol. , vol.1 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 37
    • 33847723000 scopus 로고    scopus 로고
    • Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia
    • Nuttall R.K., Silva C., Hader W., Bar-Or A., Patel K.D., Edwards D.R., and Yong V.W. Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia. Glia 5 (2007) 516-526
    • (2007) Glia , vol.5 , pp. 516-526
    • Nuttall, R.K.1    Silva, C.2    Hader, W.3    Bar-Or, A.4    Patel, K.D.5    Edwards, D.R.6    Yong, V.W.7
  • 38
    • 0033215979 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes
    • Oh L.Y., Larsen P.H., Krekoski C.A., Edwards D.R., Donovan F., Werb Z., and Yong V.W. Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes. J. Neurosci. 19 (1999) 8464-8475
    • (1999) J. Neurosci. , vol.19 , pp. 8464-8475
    • Oh, L.Y.1    Larsen, P.H.2    Krekoski, C.A.3    Edwards, D.R.4    Donovan, F.5    Werb, Z.6    Yong, V.W.7
  • 39
    • 0027169231 scopus 로고
    • Leukocyte gelatinase B cleavage releases encephalitogens from human myelin basic protein
    • Proost P., Van Damme J., and Opdenakker G. Leukocyte gelatinase B cleavage releases encephalitogens from human myelin basic protein. Biochem. Biophys. Res. Commun. 3 (1993) 1175-1181
    • (1993) Biochem. Biophys. Res. Commun. , vol.3 , pp. 1175-1181
    • Proost, P.1    Van Damme, J.2    Opdenakker, G.3
  • 40
    • 0036709244 scopus 로고    scopus 로고
    • Comparison of intravenous immunoglobulin preparations on microglial function in vitro: more potent immunomodulatory capacity of an IgM/IgA-enriched preparation
    • Pul R., Nguyen D., Schmitz U., Marx P., and Stangel M. Comparison of intravenous immunoglobulin preparations on microglial function in vitro: more potent immunomodulatory capacity of an IgM/IgA-enriched preparation. Clin. Neuropharmacol. 5 (2002) 254-259
    • (2002) Clin. Neuropharmacol. , vol.5 , pp. 254-259
    • Pul, R.1    Nguyen, D.2    Schmitz, U.3    Marx, P.4    Stangel, M.5
  • 41
    • 0036737795 scopus 로고    scopus 로고
    • Matrix metalloproteinases in neuroinflammation
    • Rosenberg G.A. Matrix metalloproteinases in neuroinflammation. Glia 3 (2002) 279-291
    • (2002) Glia , vol.3 , pp. 279-291
    • Rosenberg, G.A.1
  • 42
    • 17044372776 scopus 로고    scopus 로고
    • Matrix metalloproteinases biomarkers in multiple sclerosis
    • Rosenberg G.A. Matrix metalloproteinases biomarkers in multiple sclerosis. Lancet 9467 (2005) 1291-1293
    • (2005) Lancet , vol.9467 , pp. 1291-1293
    • Rosenberg, G.A.1
  • 43
    • 0036840967 scopus 로고    scopus 로고
    • Intravenous gamma globulin inhibits the production of matrix metalloproteinase-9 in macrophages
    • Shapiro S., Shoenfeld Y., Gilburd B., Sobel E., and Lahat N. Intravenous gamma globulin inhibits the production of matrix metalloproteinase-9 in macrophages. Cancer 9 (2002) 2032-2037
    • (2002) Cancer , vol.9 , pp. 2032-2037
    • Shapiro, S.1    Shoenfeld, Y.2    Gilburd, B.3    Sobel, E.4    Lahat, N.5
  • 44
    • 10444221955 scopus 로고    scopus 로고
    • IV immunoglobulins as add-on treatment to methylprednisolone for acute relapses in MS
    • Sorensen P.S., Haas J., Sellebjerg F., Olsson T., and Ravnborg M. IV immunoglobulins as add-on treatment to methylprednisolone for acute relapses in MS. Neurology 11 (2004) 2028-2033
    • (2004) Neurology , vol.11 , pp. 2028-2033
    • Sorensen, P.S.1    Haas, J.2    Sellebjerg, F.3    Olsson, T.4    Ravnborg, M.5
  • 45
    • 0035209290 scopus 로고    scopus 로고
    • Polyclonal immunoglobulins (IVIg) modulate nitric oxide production and microglial functions in vitro via Fc receptors
    • Stangel M., and Compston A. Polyclonal immunoglobulins (IVIg) modulate nitric oxide production and microglial functions in vitro via Fc receptors. J. Neuroimmunol. 1-2 (2001) 63-71
    • (2001) J. Neuroimmunol. , vol.1-2 , pp. 63-71
    • Stangel, M.1    Compston, A.2
  • 46
    • 0034237140 scopus 로고    scopus 로고
    • Normal polyclonal immunoglobulins ('IVIg') inhibit microglial phagocytosis in vitro
    • Stangel M., Joly E., Scolding N.J., and Compston D.A. Normal polyclonal immunoglobulins ('IVIg') inhibit microglial phagocytosis in vitro. J. Neuroimmunol. 1-2 (2000) 137-144
    • (2000) J. Neuroimmunol. , vol.1-2 , pp. 137-144
    • Stangel, M.1    Joly, E.2    Scolding, N.J.3    Compston, D.A.4
  • 47
    • 33750329819 scopus 로고    scopus 로고
    • Chemokine expression by astrocytes plays a role in microglia/macrophage activation and subsequent neurodegeneration in secondary progressive multiple sclerosis
    • Tanuma N., Sakuma H., Sasaki A., and Matsumoto Y. Chemokine expression by astrocytes plays a role in microglia/macrophage activation and subsequent neurodegeneration in secondary progressive multiple sclerosis. Acta Neuropathol. 2 (2006) 195-204
    • (2006) Acta Neuropathol. , vol.2 , pp. 195-204
    • Tanuma, N.1    Sakuma, H.2    Sasaki, A.3    Matsumoto, Y.4
  • 48
    • 0031964427 scopus 로고    scopus 로고
    • Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix
    • Uhm J.H., Dooley N.P., Oh L.Y., and Yong V.W. Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix. Glia 1 (1998) 53-63
    • (1998) Glia , vol.1 , pp. 53-63
    • Uhm, J.H.1    Dooley, N.P.2    Oh, L.Y.3    Yong, V.W.4
  • 50
    • 0347337774 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled pilot study of i.v. immune globulins in combination with i.v. methylprednisolone in the treatment of relapses in patients with MS
    • Visser L.H., Beekman R., Tijssen C.C., Uitdehaag B.M., Lee M.L., Movig K.L., and Lenderink A.W. A randomized, double-blind, placebo-controlled pilot study of i.v. immune globulins in combination with i.v. methylprednisolone in the treatment of relapses in patients with MS. Mult. Scler. 1 (2004) 89-91
    • (2004) Mult. Scler. , vol.1 , pp. 89-91
    • Visser, L.H.1    Beekman, R.2    Tijssen, C.C.3    Uitdehaag, B.M.4    Lee, M.L.5    Movig, K.L.6    Lenderink, A.W.7
  • 52
    • 0030472401 scopus 로고    scopus 로고
    • Quantitation of matrix metalloproteinases in cultured rat astrocytes using the polymerase chain reaction with a multi-competitor cDNA standard
    • Wells G.M., Catlin G., Cossins J.A., Mangan M., Ward G.A., Miller K.M., and Clements J.M. Quantitation of matrix metalloproteinases in cultured rat astrocytes using the polymerase chain reaction with a multi-competitor cDNA standard. Glia 4 (1996) 332-340
    • (1996) Glia , vol.4 , pp. 332-340
    • Wells, G.M.1    Catlin, G.2    Cossins, J.A.3    Mangan, M.4    Ward, G.A.5    Miller, K.M.6    Clements, J.M.7
  • 53
    • 28644435880 scopus 로고    scopus 로고
    • Metalloproteinases: mediators of pathology and regeneration in the CNS
    • Yong V.W. Metalloproteinases: mediators of pathology and regeneration in the CNS. Nat. Rev. Neurosci. 12 (2005) 931-944
    • (2005) Nat. Rev. Neurosci. , vol.12 , pp. 931-944
    • Yong, V.W.1


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