Whey protein potentiates the intestinotrophic action of glucagon-like peptide-2 in parenterally fed rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 297, Issue 5, 2009, Pages

  Liu, Xiaowen ^a   Murali, Sangita G ^a   Holst, Jens J ^b   Ney, Denise M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Dipeptidyl peptidase IV; Mucosal growth; Proglucagon; Whey protein concentrate

Indexed keywords

CASEIN; DIPEPTIDYL PEPTIDASE IV; GLUCAGON LIKE PEPTIDE 2; PROGLUCAGON; SOYBEAN PROTEIN; SUCRASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELEMENTAL DIET; ENTERIC FEEDING; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HYPOPLASIA; ILEUM; INTESTINE CRYPT; INTESTINE VILLUS; JEJUNUM; MALE; NONHUMAN; PARENTERAL NUTRITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WEIGHT GAIN; WHEY;

ANIMALS; BODY WEIGHT; DIPEPTIDYL PEPTIDASE 4; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; GLUCAGON-LIKE PEPTIDE 2; INTESTINAL MUCOSA; INTESTINES; MALE; MILK PROTEINS; MODELS, ANIMAL; PARENTERAL NUTRITION; PROGLUCAGON; RATS; RATS, SPRAGUE-DAWLEY; SUCRASE;

EID: 70449642950     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00423.2009     Document Type: Article

References (33)

1. Burrin DG, Stoll B, Guan X, Cui L, Chang X, Holst JJ. Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets. Endocrinology 146: 22-32, 2005. (Pubitemid 40051718)
2. Burrin DG, Stoll B, Jiang R, Chang X, Hartmann B, Holst JJ, Greeley GH Jr, and Reeds PJ. Minimal enteral nutrient requirements for intestinal growth in neonatal piglets: how much is enough? Am J Clin Nutr 71: 1603-1610, 2000. (Pubitemid 30395911)
3. Chabance B, Marteau P, Rambaud JC, Migliore-Samour D, Boynard M, Perrotin P, Guillet R, Jolles P, Fiat AM. Casein peptide release and passage to the blood in humans during digestion of milk or yogurt. Biochimie 80: 155-165, 1998. (Pubitemid 28185054)
4. Dahlqvist A. Method for assay of intestinal disaccharidases. Anal Biochem 7: 18-25, 1964.
5. Dahly EM, Gillingham MB, Guo Z, Murali SG, Nelson DW, Holst JJ, Ney DM. Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection. Am J Physiol Gastrointest Liver Physiol 284: G670-G682, 2003. (Pubitemid 36343217)
6. Dahly EM, Guo Z, Ney DM. Alterations in enterocyte proliferation and apoptosis accompany TPN-induced mucosal hypoplasia and IGF-I-induced hyperplasia in rats. J Nutr 132: 2010-2014, 2002. (Pubitemid 34742892)
7. Dahly EM, Guo Z, Ney DM. IGF-I augments resection-induced mucosal hyperplasia by altering enterocyte kinetics. Am J Physiol Regul Integr Comp Physiol 285: R800-R808, 2003. (Pubitemid 37169142)
8. Dube PE, Brubaker PL. Frontiers in glucagon-like peptide-2: multiple actions, multiple mediators. Am J Physiol Endocrinol Metab 293: E460-E465, 2007.
9. Dube PE, Brubaker PL. Nutrient, neural and endocrine control of glucagon-like peptide secretion. Horm Metab Res 36: 755-760, 2004.
10. Dube PE, Forse CL, Bahrami J, Brubaker PL. The essential role of insulin-like growth factor-1 in the intestinal tropic effects of glucagon-like peptide-2 in mice. Gastroenterology 131: 589-605, 2006. (Pubitemid 44142460)
11. Dumoulin V, Moro F, Barcelo A, Dakka T, Cuber JC. Peptide YY, glucagon-like peptide-1, and neurotensin responses to luminal factors in the isolated vascularly perfused rat ileum. Endocrinology 139: 3780-3786, 1998. (Pubitemid 28512258)
12. Estall JL, Drucker DJ. Glucagon-like Peptide-2. Annu Rev Nutr 26: 391-411, 2006.
13. Ferrone M, Scolapio JS. Teduglutide for the treatment of short bowel syndrome. Ann Pharmacother 40: 1105-1109, 2006. (Pubitemid 43886968)
14. Gardner ML. Gastrointestinal absorption of intact proteins. Annu Rev Nutr 8: 329-350, 1988.
15. Gunnarsson PT, Winzell MS, Deacon CF, Larsen MO, Jelic K, Carr RD, Ahren B. Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice. Endocrinology 147: 3173-3180, 2006. (Pubitemid 43901106)
16. Hartmann B, Johnsen AH, Orskov C, Adelhorst K, Thim L, Holst JJ. Structure, measurement, and secretion of human glucagon-like peptide-2. Peptides 21: 73-80, 2000. (Pubitemid 30126045)
17. Jeppesen PB, Hartmann B, Thulesen J, Graff J, Lohmann J, Hansen BS, Tofteng F, Poulsen SS, Madsen JL, Holst JJ, Mortensen PB. Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon. Gastroenterology 120: 806-815, 2001. (Pubitemid 32193176)
18. Kang W, Gomez FE, Lan J, Sano Y, Ueno C, Kudsk KA. Parenteral nutrition impairs gut-associated lymphoid tissue and mucosal immunity by reducing lymphotoxin Beta receptor expression. Ann Surg 244: 392-399, 2006. (Pubitemid 44273575)
19. Koopmann MC, Nelson DW, Murali SG, Liu X, Brownfield MS, Holst JJ, Ney DM. Exogenous glucagon-like peptide-2 (GLP-2) augments GLP-2 receptor mRNA and maintains proglucagon mRNA levels in resected rats. JPEN J Parenter Enteral Nutr 32: 254-265, 2008.
20. Kudsk KA, Li J, Renegar KB. Loss of upper respiratory tract immunity with parenteral feeding. Ann Surg 223: 629-635; discussion 635-1628, 1996. (Pubitemid 26185207)
21. Labarca C, Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 102: 344-352, 1980. (Pubitemid 10115803)
22. Lasekan JB, Rivera J, Hirvonen MD, Keesey RE, Ney DM. Energy expenditure in rats maintained with intravenous or intragastric infusion of total parenteral nutrition solutions containing medium- or long-chain triglyceride emulsions. J Nutr 122: 1483-1492, 1992.
23. Liu X, Murali SG, Holst JJ, Ney DM. Enteral nutrients potentiate the intestinotrophic action of glucagon-like peptide-2 in association with increased insulin-like growth factor-I responses in rats. Am J Physiol Regul Integr Comp Physiol 295: R1794-R1802, 2008.
24. Liu X, Nelson DW, Holst JJ, Ney DM. Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome. Am J Clin Nutr 84: 1142-1150, 2006. (Pubitemid 44730386)
25. McArdle AH, Wittnich C, Freeman CR, Duguid WP. Elemental diet as prophylaxis against radiation injury. Histological and ultrastructural studies. Arch Surg 120: 1026-1032, 1985. (Pubitemid 16215216)
26. Nagatsu T, Hino M, Fuyamada H, Hayakawa T, Sakakibara S. New chromogenic substrates for X-prolyl dipeptidyl-aminopeptidase. Anal Biochem 74: 466-476, 1976.
27. Nelson DW, Murali SG, Liu X, Koopmann MC, Holst JJ, Ney DM. Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats. Am J Physiol Regul Integr Comp Physiol 294: R1175-R1184, 2008.
28. Nilsson M, Holst JJ, Bjorck IM. Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks. Am J Clin Nutr 85: 996-1004, 2007. (Pubitemid 46557914)
29. Nilsson M, Stenberg M, Frid AH, Holst JJ, Bjorck IM. Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: the role of plasma amino acids and incretins. Am J Clin Nutr 80: 1246-1253, 2004. (Pubitemid 41350685)
30. Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123: 1939-1951, 1993.
31. Reimer RA, Darimont C, Gremlich S, Nicolas-Metral V, Ruegg UT, Mace K. A human cellular model for studying the regulation of glucagon-like peptide-1 secretion. Endocrinology 142: 4522-4528, 2001. (Pubitemid 32907084)
32. Ruiz-Grande C, Pintado J, Alarcon C, Castilla C, Valverde I, Lopez- Novoa JM. Renal catabolism of human glucagon-like peptides 1 and 2. Can J Physiol Pharmacol 68: 1568-1573, 1990.
33. Xiao Q, Boushey RP, Drucker DJ, Brubaker PL. Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans. Gastroenterology 117: 99-105, 1999. (Pubitemid 29297625)