Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks

Journal of Peptide Science

Volumn 15, Issue 10, 2009, Pages 647-653

  Moccia, Maria ^a   Musumeci, Domenica ^a   Roviello, Giovanni N ^a   Fusco, Sabato ^b   Valente, Margherita ^a   Bucci, Enrico M ^a   Sapio, Roberto ^a   Pedonea, Carlo ^a   Netti, Paolo A ^b  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Microrheology; Noncovalent polymers; Pna dna building blocks; Uv cd studies

Indexed keywords

DENDRIMER; DNA; PEPTIDE NUCLEIC ACID;

ARTICLE; BASE PAIRING; BIOENGINEERING; BIOTECHNOLOGY; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENCAPSULATION; FLOW KINETICS; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; POLLUTANT; PRIORITY JOURNAL; REACTION ANALYSIS; SYNTHESIS; THERMODYNAMICS; ULTRAVIOLET SPECTROSCOPY; VISCOELASTICITY;

BASE PAIRING; CIRCULAR DICHROISM; DENDRIMERS; DNA; KINETICS; PEPTIDE NUCLEIC ACIDS; POLYMERS; RHEOLOGY; SPECTROPHOTOMETRY, ULTRAVIOLET; THERMODYNAMICS;

EID: 70449633255     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1162     Document Type: Article

References (27)

1. Boas U, Heegaard PM. Dendrimers in drug research. Chem. Soc. Rev. 2004; 33(1): 43-63.
2. Boas U, Christensen JB, Heegaard PMH. Dendrimers in Medicine and Biotechnology: New Molecular Tools. RSC Publishing: Cambridge, UK, 2006.
3. Lee CC, MacKay JA, Fréchet JM, Szoka FC. Designing dendrimers for biological applications. Nat. Biotechnol. 2005; 23(12): 1517-1526.
4. Gillies ER, Fréchet JM. Dendrimers and dendritic polymers in drug delivery. Drug Discov. Today 2005; 10(1): 35-43. (Pubitemid 40164817)
5. Svenson S, Tomalia DA. Dendrimers in biomedical applications-reflections on the field. Adv. Drug Deliv. Rev. 2005; 57: 2106-2129.
6. Kobayashi H, James D, Kawamoto S, Brechbiel MW, Star RA, Choyke PL. Dendrimer-based nano-sized contrast agents for functional renal MRI: new insights into pathogenesis of acute renal diseases. Contrast Media Mol. Imaging 2005; 1(2): 66-67.
7. Guillot-Nieckowski M, Eisler S, Diederich F. Dendritic vectors for gene transfection. New J. Chem. 2007; 31: 1111-1127.
8. Arkas M, Allabashi R, Tsiourvas D, Mattausch E, Perfler R. Organic/inorganic hybrid filters based on dendritic and cyclodextrin "Nanosponges" for the removal of organic pollutants from water. Environ. Sci. Technol. 2006; 40(8): 2771-2777.
9. Song C, Koo B, Kim C. Application of dendrimer as a new material for electrical and optical devices. Jpn. J. Appl. Phys. 2002; 41: 2735-2738. (Pubitemid 43225642)
10. Li Y, Tseng YD, Kwon SY, D'Espaux L, Bunch JS, Mceuen PL, Luo D. Controlled assembly of dendrimer-like DNA. Nat. Mater. 2004; 3: 38-42.
11. Luo D. The road from biology to materials. Mater. Today 2003; 6(11): 38-43.
12. Shchepinov MS, Mir KU, Elder JK, Frank-Kamenetskii MD, Southern EM. Oligonucleotide dendrimers: stable nano-structures. Nucleic Acids Res. 1999; 27(15): 3035-3041.
13. Luo D, Li Y, Um SH, Cu Y. A dendrimer-like DNA-based vector for dna delivery: a viral and nonviral hybrid approach. Methods Mol. Med. 2006; 127: 115-126.
14. Biondi M, Ungaro F, Quaglia F, Netti PA. Controlled drug delivery in tissue engineering. Adv. Drug Deliv. Rev. 2008; 60: 229-242. (Pubitemid 350236401)
15. Hamad-Schifferli K, Schwartz JJ, Santos AT, Zhang S, Jacobson JM. Remote electronic control of DNA hybridization through inductive coupling to an attached metal nanocrystal antenna. Nature 2002; 415: 152-155. (Pubitemid 34059512)
16. Uhlmann E, Peyman A, Breipohl G, Will DW. Synthetic polyamide nucleic acids with unusual binding properties. Angew. Chem. Int. Ed. Engl. 1998; 37: 2796-2823. (Pubitemid 29008562)
17. Silvester NC, Bushell GR, Searles DJ, Brown CL. Effect of terminal amino acids on the stability and specificity of PNA-DNA hybridization. Org. Biomol. Chem. 2007; 5(6): 917-923.
18. Wittung P, Eriksson M, Lyng R, Nielsen PE, Nordén B. Induced chirality in PNA-PNA duplexes. J. Am. Chem. Soc. 1995; 117: 10167-10173.
19. Wittung P, Nielsen PE, Norden B. Observation of a PNA/PNA/PNA triplex. J. Am. Chem. Soc. 1997; 119: 3189-3190.
20. Lagriffoule P, Wittung P, Eriksson M, Jensen KK, Norden B, Buchardt O, Nielsen PE. PNAs with a conformationally constrained chiral cyclohexyl derived backbone. Chem. Eur. J. 1997;3(6):912-919. (Pubitemid 27268757)
21. Tedeschi T, Sforza S, Dossena A, Corradini R, Marchelli R. Lysine-based peptide nucleic acids (PNAs) with strong chiral constraint: control of helix handedness and DNA binding by chirality. Chirality 2005; 17: S196-S204. (Pubitemid 40962081)
22. Gardel ML, Valentine MT, Weitz DA. In Microscale Diagnostic Techniques, Brues KS (ed.). Springer: New York, 2005.
23. Mukhopadhyay A, Granick S. Micro- and nanorheology. Curr. Opin. Colloid Interface Sci. 2001; 6: 423-429.
24. Waigh TA. Microrheology of complex fluids. Rep. Prog. Phys. 2005; 68: 685-742.
25. Ferry J. Viscoelastic Properties of Polymers. John Wiley and Sons: New York, 1980.
26. Rouse PE. A theory of the linear viscoelastic properties of dilute solutions of coiling polymers. J. Chem. Phys. 1953; 21: 1272-1280.
27. Zimm BH. Dynamics of polymer molecules in dilute solution: viscoelasticity, flow birefringence and dielectric loss. J. Chem. Phys. 1956; 24: 269-278.