The rationale for placebo-controlled Trials: Methodology and policy considerations

American Journal of Bioethics

Volumn 9, Issue 9, 2009, Pages 49-50

  Miller, Franklin G ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO;

ARTICLE; CONTROLLED CLINICAL TRIAL; ETHICS; FOOD AND DRUG ADMINISTRATION; HUMAN; METHODOLOGY; RESEARCH ETHICS; SAMPLE SIZE; UNITED STATES;

CONTROLLED CLINICAL TRIALS AS TOPIC; ETHICS, RESEARCH; HUMANS; PLACEBOS; RESEARCH DESIGN; SAMPLE SIZE; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 70449602681     PISSN: 15265161     EISSN: 15360075     Source Type: Journal    
DOI: 10.1080/15265160903098408     Document Type: Article

References (3)

1. Freedman, B., Weijer, C., and Glass, K. C. 1996. Placebo orthodoxy in clinical research I: Empirical and methodological myths. Journal of Law, Medicine, & Ethics 24: 243-251.
2. Howick, J. 2009. Questioning the methodologic superiority of 'placebo'over 'active'controlled trials. American Journal of Bioethics- Neuroscience 9(9): 34-48.
3. Leon, A. C. 2001. Can placebo controls reduce the number of non- responders in clinical trials? A power-analytic perspective. Clinical Therapeutics 23: 596-607.