메뉴 건너뛰기




Volumn 4, Issue 10, 2009, Pages

Heritability and demographic analyses in the large isolated population of val borbera suggest advantages in mapping complex traits genes

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANTHROPOMETRY; ARTICLE; BONE STRUCTURE; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; EPIDEMIOLOGICAL DATA; FAMILY; FEMALE; GENE CLUSTER; GENE MAPPING; GENEALOGY; GENETIC CORRELATION; GENETIC TRAIT; GENETIC VARIABILITY; HERITABILITY; HUMAN; ITALY; MALE; POPULATION GENETICS; CHROMOSOME MAP; CLUSTER ANALYSIS; ETHNIC AND RACIAL GROUPS; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETICS; GEOGRAPHY; PHENOTYPE;

EID: 70449597270     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007554     Document Type: Article
Times cited : (39)

References (29)
  • 1
    • 44349132708 scopus 로고    scopus 로고
    • Common and rare variants in multifactorial susceptibility to common diseases
    • Bodmer W, Bonilla C (2008) Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet 40: 695-701.
    • (2008) Nat Genet , vol.40 , pp. 695-701
    • Bodmer, W.1    Bonilla, C.2
  • 2
    • 62549085618 scopus 로고    scopus 로고
    • Human genetic variation and its contribution to complex traits
    • Frazer KA, Murray SS, Schork NJ, Topol EJ (2009) Human genetic variation and its contribution to complex traits. Nat Rev Genet 10: 241-251.
    • (2009) Nat Rev Genet , vol.10 , pp. 241-251
    • Frazer, K.A.1    Murray, S.S.2    Schork, N.J.3    Topol, E.J.4
  • 3
    • 2542446307 scopus 로고    scopus 로고
    • Isolates and their potential use in complex gene mapping efforts
    • Varilo T, Peltonen L (2004) Isolates and their potential use in complex gene mapping efforts. Curr Opin Genet Dev 14: 316-323.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 316-323
    • Varilo, T.1    Peltonen, L.2
  • 4
    • 0036556373 scopus 로고    scopus 로고
    • Genetics of population isolates
    • Arcos-Burgos M, Muenke M (2002) Genetics of population isolates. Clin Genet 61: 233-247.
    • (2002) Clin Genet , vol.61 , pp. 233-247
    • Arcos-Burgos, M.1    Muenke, M.2
  • 5
    • 33745184400 scopus 로고    scopus 로고
    • New susceptibility locus for hypertension on chromosome 8q by efficient pedigree-breaking in an Italian isolate
    • Ciullo M, Bellenguez C, Colonna V, Nutile T, Calabria A, et al. (2006) New susceptibility locus for hypertension on chromosome 8q by efficient pedigree-breaking in an Italian isolate. Hum Mol Genet 15: 1735-1743.
    • (2006) Hum Mol Genet , vol.15 , pp. 1735-1743
    • Ciullo, M.1    Bellenguez, C.2    Colonna, V.3    Nutile, T.4    Calabria, A.5
  • 6
    • 0032707163 scopus 로고    scopus 로고
    • Population choice in mapping genes for complex diseases
    • Wright AF, Carothers AD, Pirastu M (1999) Population choice in mapping genes for complex diseases. Nat Genet 23: 397-404.
    • (1999) Nat Genet , vol.23 , pp. 397-404
    • Wright, A.F.1    Carothers, A.D.2    Pirastu, M.3
  • 7
    • 0030000431 scopus 로고    scopus 로고
    • Genetic analysis of Sardinia: I. data on 12 polymorphisms in 21 linguistic domains
    • Cappello N, Rendine S, Griffo R, Mameli GE, Succa V, et al. (1996) Genetic analysis of Sardinia: I. data on 12 polymorphisms in 21 linguistic domains. Ann Hum Genet 60: 125-141.
    • (1996) Ann Hum Genet , vol.60 , pp. 125-141
    • Cappello, N.1    Rendine, S.2    Griffo, R.3    Mameli, G.E.4    Succa, V.5
  • 8
    • 57649098768 scopus 로고    scopus 로고
    • The genome-wide patterns of variation expose significant substructure in a founder population
    • Jakkula E, Rehnstrom K, Varilo T, Pietilainen OP, Paunio T, et al. (2008) The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet 83: 787-794.
    • (2008) Am J Hum Genet , vol.83 , pp. 787-794
    • Jakkula, E.1    Rehnstrom, K.2    Varilo, T.3    Pietilainen, O.P.4    Paunio, T.5
  • 10
    • 17944372318 scopus 로고    scopus 로고
    • Archival, demographic and genetic studies define a Sardinian sub-isolate as a suitable model for mapping complex traits
    • Angius A, Melis PM, Morelli L, Petretto E, Casu G, et al. (2001) Archival, demographic and genetic studies define a Sardinian sub-isolate as a suitable model for mapping complex traits. Hum Genet 109: 198-209.
    • (2001) Hum Genet , vol.109 , pp. 198-209
    • Angius, A.1    Melis, P.M.2    Morelli, L.3    Petretto, E.4    Casu, G.5
  • 11
    • 37149051777 scopus 로고    scopus 로고
    • Estimates of genetic and environmental contribution to 43 quantitative traits support sharing of a homogeneous environment in an isolated population from South Tyrol, Italy
    • Marroni F, Grazio D, Pattaro C, Devoto M, Pramstaller P (2008) Estimates of genetic and environmental contribution to 43 quantitative traits support sharing of a homogeneous environment in an isolated population from South Tyrol, Italy. Hum Hered 65: 175-182.
    • (2008) Hum Hered , vol.65 , pp. 175-182
    • Marroni, F.1    Grazio, D.2    Pattaro, C.3    Devoto, M.4    Pramstaller, P.5
  • 12
    • 33748501230 scopus 로고    scopus 로고
    • Heritability of serum iron, ferritin and transferrin saturation in a genetically isolated population, the Erasmus Rucphen Family (ERF) Study
    • Njajou OT, Alizadeh BZ, Aulchenko Y, Zillikens MC, Pols HA, et al. (2006) Heritability of serum iron, ferritin and transferrin saturation in a genetically isolated population, the Erasmus Rucphen Family (ERF) Study. Hum Hered 61: 222-228.
    • (2006) Hum Hered , vol.61 , pp. 222-228
    • Njajou, O.T.1    Alizadeh, B.Z.2    Aulchenko, Y.3    Zillikens, M.C.4    Pols, H.A.5
  • 13
    • 58149161560 scopus 로고    scopus 로고
    • Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
    • Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, et al. (2009) Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 41: 47-55.
    • (2009) Nat Genet , vol.41 , pp. 47-55
    • Aulchenko, Y.S.1    Ripatti, S.2    Lindqvist, I.3    Boomsma, D.4    Heid, I.M.5
  • 14
    • 58149159573 scopus 로고    scopus 로고
    • Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, et al. (2009) Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet 41: 35-46.
    • Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, et al. (2009) Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet 41: 35-46.
  • 15
    • 33748039452 scopus 로고    scopus 로고
    • Heritability of cardiovascular and personality traits in 6,148 Sardinians
    • Pilia G, Chen WM, Scuteri A, Orru M, Albai G, et al. (2006) Heritability of cardiovascular and personality traits in 6,148 Sardinians. PLoS Genet 2: e132.
    • (2006) PLoS Genet , vol.2
    • Pilia, G.1    Chen, W.M.2    Scuteri, A.3    Orru, M.4    Albai, G.5
  • 16
    • 53849098349 scopus 로고    scopus 로고
    • Tepper BJ, Koelliker Y, Zhao L, Ullrich NV, Lanzara C, et al. (2008) Variation in the bitter-taste receptor gene TAS2R38, and adiposity in a genetically isolated population in Southern Italy. Obesity (Silver Spring) 16: 2289-2295.
    • Tepper BJ, Koelliker Y, Zhao L, Ullrich NV, Lanzara C, et al. (2008) Variation in the bitter-taste receptor gene TAS2R38, and adiposity in a genetically isolated population in Southern Italy. Obesity (Silver Spring) 16: 2289-2295.
  • 19
    • 51849137780 scopus 로고    scopus 로고
    • Prevalence and heritability of the metabolic syndrome and its individual components in a Dutch isolate: The Erasmus Rucphen Family study
    • Henneman P, Aulchenko YS, Frants RR, van Dijk KW, Oostra BA, et al. (2008) Prevalence and heritability of the metabolic syndrome and its individual components in a Dutch isolate: the Erasmus Rucphen Family study. J Med Genet 45: 572-577.
    • (2008) J Med Genet , vol.45 , pp. 572-577
    • Henneman, P.1    Aulchenko, Y.S.2    Frants, R.R.3    van Dijk, K.W.4    Oostra, B.A.5
  • 20
    • 0035023261 scopus 로고    scopus 로고
    • Broad and narrow heritabilities of quantitative traits in a founder population
    • Abney M, McPeek MS, Ober C (2001) Broad and narrow heritabilities of quantitative traits in a founder population. Am J Hum Genet 68: 1302-1307.
    • (2001) Am J Hum Genet , vol.68 , pp. 1302-1307
    • Abney, M.1    McPeek, M.S.2    Ober, C.3
  • 22
    • 35948931767 scopus 로고    scopus 로고
    • Bone mineral density in adults with the metabolic syndrome: Analysis in a population-based U.S. sample
    • Kinjo M, Setoguchi S, Solomon DH (2007) Bone mineral density in adults with the metabolic syndrome: analysis in a population-based U.S. sample. J Clin Endocrinol Metab 92: 4161-4164.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 4161-4164
    • Kinjo, M.1    Setoguchi, S.2    Solomon, D.H.3
  • 25
    • 64549083234 scopus 로고    scopus 로고
    • Use of a genetic isolate to identify rare disease variants: C7 on 5p associated with MS
    • Kallio SP, Jakkula E, Purcell S, Suvela M, Koivisto K, et al. (2009) Use of a genetic isolate to identify rare disease variants: C7 on 5p associated with MS. Hum Mol Genet 18: 1670-1683.
    • (2009) Hum Mol Genet , vol.18 , pp. 1670-1683
    • Kallio, S.P.1    Jakkula, E.2    Purcell, S.3    Suvela, M.4    Koivisto, K.5
  • 26
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J (1998) Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62: 1198-1211.
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 27
    • 34547628858 scopus 로고    scopus 로고
    • Family-based association tests for genomewide association scans
    • Chen WM, Abecasis GR (2007) Family-based association tests for genomewide association scans. Am J Hum Genet 81: 913-926.
    • (2007) Am J Hum Genet , vol.81 , pp. 913-926
    • Chen, W.M.1    Abecasis, G.R.2
  • 28
    • 0042387785 scopus 로고    scopus 로고
    • Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus
    • Bourgain C, Hoffjan S, Nicolae R, Newman D, Steiner L, et al. (2003) Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet 73: 612-626.
    • (2003) Am J Hum Genet , vol.73 , pp. 612-626
    • Bourgain, C.1    Hoffjan, S.2    Nicolae, R.3    Newman, D.4    Steiner, L.5
  • 29
    • 40049106184 scopus 로고    scopus 로고
    • Jenti: An efficient tool for mining complex inbred genealogies
    • Falchi M, Fuchsberger C (2008) Jenti: an efficient tool for mining complex inbred genealogies. Bioinformatics 24: 724-726.
    • (2008) Bioinformatics , vol.24 , pp. 724-726
    • Falchi, M.1    Fuchsberger, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.