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Volumn 37, Issue SUPPL. 1, 2009, Pages 1-4

Drug discovery and development tomorrow - Changing the mindset

(1)  Coleman, Robert A a  

a NONE

Author keywords

Drug discovery and development; Human focus; Human tissues and organs; Success rate

Indexed keywords

BECLOMETASONE; BECLOMETASONE DIPROPIONATE; BIOMATERIAL; CEFTAZIDINE; CEFUROXIME; FLUTICASONE PROPIONATE; LABETALOL; ONDANSETRON; RANITIDINE; SALBUTAMOL; SALMETEROL; SALMETEROL XINAFOATE; SUMATRIPTAN SUCCINATE; UNCLASSIFIED DRUG; XOFRAN;

EID: 70449591024     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290903701s02     Document Type: Conference Paper
Times cited : (4)

References (27)
  • 1
    • 43949101389 scopus 로고    scopus 로고
    • Rebuilding the R&D engine in big pharma
    • Garnier, J-P. (2008). Rebuilding the R&D engine in big pharma. Harvard Business Review 86 (5), 68-76.
    • (2008) Harvard Business Review , vol.86 , Issue.5 , pp. 68-76
    • Garnier, J.-P.1
  • 2
    • 72249113895 scopus 로고    scopus 로고
    • Drug companies: Big Pharma besieged from all sides
    • Available at: Accessed 09.03. 09. London, UK: Guardian News and Media Group Ltd
    • Kollewe, J. (2008). Drug companies: Big Pharma besieged from all sides. The Guardian. Available at: http://www.guardian.co.uk/business/2008/aug/30/ pharmaceuticals.medicalresearch (Accessed 09.03. 09). London, UK: Guardian News and Media Group Ltd.
    • (2008) The Guardian
    • Kollewe, J.1
  • 3
    • 0024566835 scopus 로고
    • The challenge of drug discovery
    • Jack, D. (1989). The challenge of drug discovery. Drug Design & Delivery 4, 167-186.
    • (1989) Drug Design & Delivery , vol.4 , pp. 167-186
    • Jack, D.1
  • 5
    • 0021025586 scopus 로고
    • 2-antagonists - Past, present and future
    • Brittain, R.T. & Jack, D. (1983). Histamine H2-antagonists - past, present and future. Journal of Clinical Gastroenterology 5, Suppl. 1, 71-79. (Pubitemid 14214243)
    • (1983) Journal of Clinical Gastroenterology , vol.5 , Issue.SUPPL. 1 , pp. 71-79
    • Brittain, R.T.1    Jack, D.2
  • 6
    • 0031977044 scopus 로고    scopus 로고
    • 2-agonists in asthma therapy
    • Moore, R.H., Khan, A. & Dickey, B.F. (1998). Long-acting inhaled beta2-agonists in asthma therapy. Chest 113, 1095-1108. (Pubitemid 28216460)
    • (1998) Chest , vol.113 , Issue.4 , pp. 1095-1108
    • Moore, R.H.1    Khan, A.2    Dickey, B.F.3
  • 8
    • 0031428470 scopus 로고    scopus 로고
    • Interspecies comparisons of liver carcinogenesis: Implications for cancer risk assessment
    • Grisham, J.W. (1997). Interspecies comparisons of liver carcinogenesis: implications for cancer risk assessment. Carcinogenesis 18, 59-81.
    • (1997) Carcinogenesis , vol.18 , pp. 59-81
    • Grisham, J.W.1
  • 14
    • 59649105834 scopus 로고    scopus 로고
    • Genetic basis of inter- and intrastrain differences in diazepam p-hydroxylation in rats
    • advance online publication, 29.10.08 (DOI: 10.1124/dmd.108.024273)
    • Sakai, N., Saito K., Sakamoto, K.Q., Ishizuka, M. & Fujita, S. (2008). Genetic basis of inter- and intrastrain differences in diazepam p-hydroxylation in rats. Drug Metabolism & Disposition advance online publication, 29.10.08 (DOI: 10.1124/dmd.108.024273).
    • (2008) Drug Metabolism & Disposition
    • Sakai, N.1    Saito, K.2    Sakamoto, K.Q.3    Ishizuka, M.4    Fujita, S.5
  • 15
    • 0032768264 scopus 로고    scopus 로고
    • Current animal models are not predictive for clinical asthma
    • Coleman, R.A. (1999). Current animal models are not predictive for clinical asthma. Pulmonary Pharmacology & Therapeutics 12, 87-89.
    • (1999) Pulmonary Pharmacology & Therapeutics , vol.12 , pp. 87-89
    • Coleman, R.A.1
  • 17
    • 64249119491 scopus 로고    scopus 로고
    • Mouse models of allergic asthma: Acute and chronic allergen challenge
    • Nials, A.T. & Uddin, S. (2008). Mouse models of allergic asthma: acute and chronic allergen challenge. Disease Models & Mechanisms 1, 213-220.
    • (2008) Disease Models & Mechanisms , vol.1 , pp. 213-220
    • Nials, A.T.1    Uddin, S.2
  • 18
    • 50849140491 scopus 로고    scopus 로고
    • Modeling of asthma, COPD and cystic fibrosis in sheep
    • Abraham, W.M. (2008). Modeling of asthma, COPD and cystic fibrosis in sheep. Pulmonary Pharmacology & Therapeutics 21, 743-754.
    • (2008) Pulmonary Pharmacology & Therapeutics , vol.21 , pp. 743-754
    • Abraham, W.M.1
  • 20
    • 33749991402 scopus 로고    scopus 로고
    • Global similarity and local divergence in human and mouse gene co-expression networks
    • DOI: 10.1186/1471-2148-6-70
    • Tsaparas, P., Mariño-Ramírez, L., Bodenreider, O., Koonin, E.V. & Jordan, I.K. (2006). Global similarity and local divergence in human and mouse gene co-expression networks. BMC Evolutionary Biology 12, 70. (DOI: 10.1186/1471-2148-6-70).
    • (2006) BMC Evolutionary Biology , vol.12 , pp. 70
    • Tsaparas, P.1    Mariño-Ramírez, L.2    Bodenreider, O.3    Koonin, E.V.4    Jordan, I.K.5
  • 21
    • 72249113474 scopus 로고    scopus 로고
    • Safer Medicines Campaign website. Available at: Accessed 11.03.09. London, UK: Safer Medicines Campaign/Safer Medicines Trust
    • Safer Medicines Campaign website. Available at: http://www. safermedicines.org (Accessed 11.03.09). London, UK: Safer Medicines Campaign/Safer Medicines Trust.
  • 22
    • 15744366276 scopus 로고    scopus 로고
    • The legal and ethical considerations relating to the supply and use of human tissue for biomedical research: A UK perspective
    • Wilkinson, J. & Coleman, R.A. (2001). The legal and ethical considerations relating to the supply and use of human tissue for biomedical research: a UK perspective. Journal of Commercial Biotechnology 8, 140-146.
    • (2001) Journal of Commercial Biotechnology , vol.8 , pp. 140-146
    • Wilkinson, J.1    Coleman, R.A.2
  • 23
    • 33747379538 scopus 로고    scopus 로고
    • undated. Available at: Accessed 11.03.09. London, UK: Human Tissue Authority
    • Human Tissue Authority (undated). Human Tissue Act. Available at: www.hta.gov.uk/about-hta/human-tissue-act.cfm (Accessed 11.03.09). London, UK: Human Tissue Authority.
    • Human Tissue Act
  • 24
    • 72249092378 scopus 로고    scopus 로고
    • Human Tissue Authority website. Available at: Accessed 11.03.09. London, UK: Human Tissue Authority
    • Human Tissue Authority website. Available at: http://www.hta.gov.uk/ (Accessed 11.03.09). London, UK: Human Tissue Authority.
  • 26
    • 72249102882 scopus 로고    scopus 로고
    • Ministers struggle to combat shortages
    • Anon. 4 January 2009. Available at: Accessed 11.03.09. London, UK: Times Newspapers Ltd.
    • Anon. (2009). Ministers struggle to combat shortages. The Sunday Times, 4 January 2009. Available at: http://www.timesonline.co.uk/to]/news/uk/health/ article5439441.ece (Accessed 11.03.09). London, UK: Times Newspapers Ltd.
    • (2009) The Sunday Times
  • 27
    • 72249083809 scopus 로고    scopus 로고
    • Available at: Accessed 11.03.09. London, UK: Telegraph Media Group Ltd
    • Smith, R. (2008). Presumed consent law change 'not necessary' to donate organs. Available at: http://www.telegraph.co.uk/health/2228818/Presumed- consent-law-change-not-necessary-to-donate-organs.html (Accessed 11.03.09). London, UK: Telegraph Media Group Ltd.
    • (2008) Presumed Consent Law Change 'Not Necessary' to Donate Organs
    • Smith, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.