The dual-route hypothesis: Evaluating a neurocomputational model of fear conditioning in rats

Connection Science

Volumn 21, Issue 1, 2009, Pages 15-37

  Lowe, Robert ^a   Humphries, Mark ^b   Ziemke, Tom ^a  

^a UNIVERSITY OF SKÖVDE   (Sweden)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Amygdala; Dual route hypothesis; Emotion; Fear; Population coding

Indexed keywords

AMYGDALA; DUAL-ROUTE HYPOTHESIS; EMOTION; FEAR; POPULATION CODING;

EID: 70449579168     PISSN: 09540091     EISSN: 13600494     Source Type: Journal    
DOI: 10.1080/09540090802414085     Document Type: Article

References (51)

1. Armony, J.L. (2005), 'Computational Models of Emotion,' in Proceedings of the IEEE International Joint Conference on Neural Networks, pp. 1598-1602.
2. Armony, J.L., Servan-Schreiber, D., Cohen, J.D., and LeDoux, J.E. (1995), 'AnAnatomically Constrained Neural Network Model of Fear Conditioning,' Behavioral Neuroscience, 109, 246-257.
3. Armony, J.L., Servan-Schreiber, D., Cohen, J.D., and LeDoux, J.E. (1997a), 'Computational Modeling of Emotion: Explorations Through the Anatomy and Physiology of Fear Conditioning,' Trends in Cognitive Science, 1, 28-34.
4. Armony, J.L., Servan-Schreiber, D., Romanski, L.M., Cohen, J.D., and LeDoux, J.E. (1997b), 'Stimulus Generalization of Fear Responses: Effects of Auditory Cortex Lesions in a Computational Model and in Rats,.Cerebral Cortex, 7, 157-165.
5. Armony, J.L., Quirk, G.J., and LeDoux, J.E. (1998), 'Differential Effects of Amygdala Lesions on Early and Late Plastic Components of Auditory Cortex Spike Trains during Fear Conditioning,' The Journal of Neuroscience, 18, 2592-2601.
6. Arnold, M.B. (1960) Emotion and Personality, New York: Columbia University Press.
7. Balleine, B.W., Kilcross, A.S., and Dickinson, A. (2003), 'The Effects of Lesions of the Basolateral Amygdala on Instrumental Conditioning,' The Journal of Neuroscience, 23, 666-675.
8. Balkenius, C. and Morén, J. (2001), 'Emotional Learning: A Computational Model of the Amygdala,' Cybernetics and Systems, 32, 611-636.
9. Bechara, A., Damasio, H., and Damasio, A.R., (2003), 'Role of the Amygdala in Decision-Making,' Annals of the New York Academy of Sciences, 985, 356-69.
10. Bordi, F. and LeDoux, J.E. (1994), 'Response Properties of Single Units in Areas of Rat Auditory Thalamus that Project to the Amygdala,' Experimental Brain Research, 98, 275-286.
11. Cardinal, R., Parkinson, J., Hall, J., and Everitt, B. (2002), 'Emotion and Motivation: The Role of the Amygdala, Ventral Striatum, and Prefrontal Cortex,' Neuroscience and Biobehavioral Reviews, 26, 321-352.
12. Corcoran, K.A., Desmond, T.J., Frey, K.A., and Maren, S. (2005), 'Hippocampal Inactivation Disrupts the Acquisition and Contextual Encoding of Fear Extinction,' The Journal of Neuroscience, 25, 8978-8987.
13. Corcoran, K.A. and Maren, S. (2001), 'Hippocampal Inactivation Disrupts Contextual Retrieval of Fear Memory after Extinction,' The Journal of Neuroscience, 21, 1720-1726.
14. Cruikshank, S.J., Edeline, J., and Weinberger, N.M. (1992), 'Stimulation at a Site of Auditory-Somatosensory Convergence in the Medial Geniculate Nucleus is an Effective Unconditioned Stimulus for Fear Conditioning,' Behavioral Neuroscience, 106, 471-483.
15. Damasio, A. (2003), Looking for Spinoza: Joy, Sorrow, and the Feeling Brain, Orlando, FL: Harcourt.
16. Davis, M. (2006), 'The Role of the Amygdala in Conditioned and Unconditioned Fear and Anxiety,' in The Amgydala: A Functional Analysis (2nd ed.) ed. J.P. Aggleton, New York: Oxford University Press, pp. 213-288.
17. Fellous, J.-M., Armony, J.L., and LeDoux, J.E. (2003), 'Emotional Circuits and Computational Neuroscience,' in The Handbook of Brain Theory and Neural Networks, (2nd ed.) ed. M.A. Arbib, Cambridge, MA: The MIT Press, pp. 398-401.
18. Fellous, J.-M. and LeDoux, J.E. (2005), 'Toward Basic Principles for Emotional Processing: What the Fearful Brain Tells the Robot,' in Who Needs Emotions? The Brain Meets the Robot, eds. J.-M. Fellous and M.A. Arbib, Eds, New York: Oxford University Press, pp. 79-117.
19. Freeman, W.J. (2000), How Brains Make Up Their Minds, New York: Columbia University Press.
20. Gewirtz, J.C., McNish, K.A., and Davis, M. (2000), 'Is the Hippocampus Necessary for Fear Conditioning?' Behavioural Brain Research, 110, 83-95.
21. Klopf, A.H., Morgan, J.S., and Weaver, S.E. (1993), 'A Hierarchical Network of Control Systems that Learn: Modeling Nervous System Function During Classical and Instrumental Conditioning,' Adaptive Behavior, 1, 263-319.
22. Lazarus, R.S. (1991) Emotion and Adaptation, New York: Oxford University Press.
23. LeBar, K.S. and LeDoux, J.E. (1996), 'Partial Disruption of Fear Conditioning in Rats with UnilateralAmygdala Damage: Correspondence with Unilateral Temporal Lobectomy in Humans,' Behavioral Neuroscience, 110, 991-997.
24. LeDoux, J.E. (1990), 'Information Flow from Sensation to Emotion: Plasticity in the Neural Computation of Stimulus Value,' in Learning and Computational Neuroscience: Foundations of Adaptive Networks, eds. M. Gabriel and J. Moore, Cambridge, MA: MIT Press, pp. 3-51.
25. LeDoux, J.E. (1992), 'Brain Mechanisms of Emotion and Emotional Learning,' Current Opinion in Neurobiology, 2, 191-197.
26. LeDoux, J.E. (1995), 'Emotion: Clues from the Brain,' Annual Review of Psychology, 46, 209-235.
27. LeDoux, J.E. (1996), The Emotional Brain, New York: Simon & Schuster.
28. LeDoux, J.E. (2000), 'Emotion Circuits in the Brain,' Annual Review of Neuroscience, 23, 155-184.
29. LeDoux, J.E. (2006), 'TheAmygdala and Emotion:AView Through Fear,' in The Amygdala: A Functional Analysis, (2nd ed.) ed. J.P. Aggleton, Oxford: Oxford University Press, pp. 289-310.
30. Lewis, M. (2005), 'Bridging emotion theory and neurobiology through dynamic systems modeling,' Behavioral and Brain Sciences, 28, 169-194.
31. Lowe, R., Morse, A., and Ziemke, T. (2008), 'An Enactive Approach for Modeling Cognition, Emotion and Autonomy: Predictive Regulation at Different Levels of Organizational Complexity' (Submitted).
32. Mannella, F., Mirolli, M., and Baldassarre, G. (2007), 'The Role of Amygdala in Devaluation: A Model Tested with a Simulated Robot,' in Proceedings of the Seventh International Conference on Epigenetic Robotics, Lund University Cognitive Studies, pp. 77-84.
33. Mannella, F., Zappacosta, S., Mirolli, M., and Baldassarre, G. (2008), 'A Computational Model of theAmygdala Nuclei's Role in Second Order Conditioning,' in Proceedings of the Tenth International Conference on Simulation of Adaptive Behavior, pp. 321-330.
34. Morén, J. (2002). Learning and Emotion, Ph.D. thesis, Lund University.
35. Morén, J. and Balkenius, C. (2000), 'A Computational Model of Emotional Learning in the Amygdala,' in Proceedings of the Sixth International Conference on Simulation of Adaptive Behavior, Cambridge, MA: MIT Press, pp. 383-391.
36. Morse, T., Lowe, R., and Ziemke, T. (2005), 'Towards an Enactive Cognitive Architecture,' International Conference on Cognitive Systems, presentation.
37. Mowrer, O. (1973) Learning Theory and Behavior, New York: Wiley.
38. Öhman, A., Flykt, A., and Lundqvist, D. (2000), 'Unconscious Emotion: Evolutionary Perspectives, Psychophysiological Data and Neuropsychological Mechanisms,' in Cognitive Neuroscience of Emotion, eds. R.D. Lane and L. Nadel, Oxford: Oxford University Press, pp. 296-327.
39. Panksepp, J. (1998) Affective Neuroscience, Oxford: Oxford University Press.
40. Pinault, D. and Deschenes, M. (1998), 'Anatomical Evidence for a Mechanism of Lateral Inhibition in the Rat Thalamus,' European Journal of Neuroscience, 10, 3462-3469.
41. Pitkänen, A. (2006), 'Connectivity of the Rat Amygdaloid Complex,' in The Amygdala: A Functional Analysis, (2nd ed.) ed. J.P. Aggleton, Oxford: Oxford University Press, pp. 31-116.
42. Pitkänen, A., Savander, V., and LeDoux, J.E.(1997), 'Organization of Intra-amygdaloid Circuitries in the Rat: An Emerging Framework for Understanding Functions of the Amgydala,' Trends in Neuroscience, 20, 517-523.
43. Rolls, E. (1999), The Brain and Emotion, Oxford: Oxford University Press.
44. Rolls, E. (2005a), Emotion Explained, Oxford: Oxford University Press.
45. Rolls, E. (2005b), 'What Are Emotions, Why DoWe Have Emotions, and What is their Computational Basis in the Brain?' in Who Needs Emotions? The Brain Meets the Robot, eds. J-M. Fellous and M.A. Arbib, Oxford: Oxford University Press, pp. 117-146.
46. Sapolsky, R.M. (2007), 'Stress, Stress-related Disease, and Emotional Regulation,' in Handbook of Emotion Regulation, ed. J.J. Gross, New York, London: The Guilford Press, pp. 606-615.
47. Scherer, K.R. (2000), 'Emotions as Episodes of Subsytem Synchronization Driven by Non-linear Appraisal Processes,' in Emotion, Development, and Self-organization, eds. M.D. Lewis and I. Granic, Cambridge: Cambridge University Press, pp. 70-99
48. Stent, G.S. (1973), 'A Physiological Mechanism for Hebb's Postulate of Learning,' Proceedings of the National Academy of Sciences, USA, 70, 997-1001.
49. Wehrle, T. and Scherer, K.R. (2001), 'Toward Computational Modeling of Appraisal Theories,' in Appraisal Processes in Emotion: Theory, Methods, Research, eds. K.R. Scherer, A. Schorr, and T. Johnstone, Oxford: Oxford University Press, pp. 350-368.
50. Winstanley, C.A., Theobald, D.E.H., Cardinal, R.N., and Robbins, T.W. (2004), 'Contrasting Roles of Basolateral Amygdala and Orbitofrontal Cortex in Impulsive Choice,' The Journal of Neuroscience, 24, 4718-4722.
51. Ziemke, T., and Lowe, R., 'On the Role of Emotion in Embodied Cognitive Architectures: From Organisms to Robots', Cognitive Computation, 1, in press.