One billion years of p53/p63/p73 evolution

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 42, 2009, Pages 17609-17610

  Belyi, Vladimir A ^a   Levine, Arnold J ^a  

^a INSTITUTE FOR ADVANCED STUDY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; PROTEIN P63; PROTEIN P73; TRANSCRIPTION FACTOR;

ANEMONE; DNA BINDING; DNA DAMAGE; FISH; GENOME; HETEROZYGOSITY; INVERTEBRATE; MOLECULAR EVOLUTION; MUTATION; NEOPLASM; NONHUMAN; NOTE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SHARK;

ANIMALS; CAENORHABDITIS ELEGANS PROTEINS; DNA-BINDING PROTEINS; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; HUMANS; MUTATION; NEOPLASMS; NUCLEAR PROTEINS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 70449562133     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0910634106     Document Type: Note

References (23)

1. Joerger AC, et al. (2009) Structural evolution of p53, p63 and p73: Implications for heterotetramer formation. Proc Natl Acad Sci USA 106:17705-17710.
2. Vogelstein B, Lane D, Levine AJ (2000) Surfing the p53 network. Nature 408:307-310.
3. Malkin D, et al. (1990) Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238. (Pubitemid 120031831)
4. Yang A, et al. (1999) p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398:714-718. (Pubitemid 29197650)
5. Celli J, et al. (1999) Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome. Cell 99:143-153. (Pubitemid 29491781)
6. Yang A (2000) p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumors. Nature 404:99-103.
7. Suh E-K, et al. (2006) p63 protects the female germ line during meiotic arrest. Nature 444:624-628.
8. Tommasini R (2008) Tap73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev 22:2677-2691.
9. Muller AJ, Teresky AK, Levine AJ (2000) A male germ cell tumor-susceptibility-determining locus, pgct1, identified on murine chromosome 13. Proc Natl Acad Sci USA 97:8421-8426.
10. Hu W, Feng Z, Teresky AK, Levine AJ (2007) p53 regulates maternal reproduction through LIF. Nature 450:721-724. (Pubitemid 350207678)
11. Kang H-J, et al. (2009) Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans. Proc Natl Acad Sci USA 106:9761-9766.
12. Belyi VA, et al. (2009) The origins and evolution of the p53 family of genes. The p53 Family of Genes, eds Levine AJ, Lane D (Cold Spring Harbor Lab Press, Cold Spring Harbor, NY), in press.
13. Utikal J, et al. (2009) Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature 460:1145-1148.
14. Marion RM, et al. (2009) A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature 460:1149-1153.
15. Li H, et al. (2009) The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 460:1136-1139.
16. Hong H, et al. (2009) Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460:1132-1135.
17. Kawamura T, et al. (2009) Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 460:1140-1144.
18. Jeffrey PD, Gorina S, Pavletich NP (1995) Crystal structure of the tetramerization domain of the p53 tumor Suppressor at 1.7 ångstroms, Science 267:1498-1502.
19. Dittmer D, et al. (1993) Gain of function mutations in p53. Nat Genet 4:42-46.
20. Liu G, et al. (2000) High metastatic potential in mice inheriting a targeted p53 missense mutation. Proc Natl Acad Sci USA 97:4174-4179. (Pubitemid 30226106)
21. Irwin MS, et al. (2003) Chemosensitivity linked to p73 function. 3:403-410.
22. Irwin MS, Kaelin WG (2001) Role of newer p53 family proteins in malignancy. Apoptosis 6:17-22.
23. Marin MC, et al. (2000) A common polymorphism acts as an intragenic modifier of mutant p53 behaviour. Nat Genet 25:47-54.