Soluble total human leukocyte antigen class I and human leukocyte antigen-G molecules in kidney and kidney/pancreas transplantation

Human Immunology

Volumn 70, Issue 12, 2009, Pages 995-999

  Rebmann, Vera ^a   Bartsch, Diana ^b   Wunsch, Andreas ^b   Möllenbeck, Petra ^a,b   Golda, Thomas ^b   Viebahn, Richard ^b   Grosse Wilde, Hans ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b ST JOSEF HOSPITAL   (Germany)

Author keywords

Graft rejection; Kidney transplantation; Kidney pancreas transplantation; Prognostic marker; Soluble HLA G; Total soluble HLA class I

Indexed keywords

HLA ANTIGEN CLASS 1; HLA G ANTIGEN; SOLUBLE HLA G ANTIGEN; UNCLASSIFIED DRUG;

ADULT; AGE; ANTIGEN EXPRESSION; ARTICLE; BODY MASS; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GRAFT RECIPIENT; GRAFT REJECTION; GRAFT SURVIVAL; HLA MATCHING; HUMAN; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY PANCREAS TRANSPLANTATION; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; RECIPIENT; RETRANSPLANTATION; RISK FACTOR;

BIOLOGICAL MARKERS; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; KIDNEY TRANSPLANTATION; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PANCREAS TRANSPLANTATION;

EID: 70449534881     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.07.016     Document Type: Article

References (50)

1. Lopez-Botet M., Bellon T., Llano M., Navarro F., Garcia P., and de Miguel M. Paired inhibitory and triggering NK cell receptors for HLA class I molecules. Hum Immunol 61 (2000) 7-17
2. Lopez-Botet M., Llano M., Navarro F., and Bellon T. NK cell recognition of non-classical HLA class I molecules. Semin Immunol 12 (2000) 109-119
3. Lopez-Botet M., Navarro F., and Llano M. How do NK cells sense the expression of HLA-G class Ib molecules?. Semin Cancer Biol 9 (1999) 19-26
4. Gao G.F., Willcox B.E., Wyer J.R., et al. Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha. J Biol Chem 275 (2000) 15232-15238
5. Yan W.H., and Fan L.A. Residues Met76 and Gln79 in HLA-G alpha1 domain involve in KIR2DL4 recognition. Cell Res 15 (2005) 176-182
6. Rajagopalan S., and Long E.O. A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells. J Exp Med 189 (1999) 1093-1100
7. Fons P., Chabot S., Cartwright J.E., et al. Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells. Blood 108 (2006) 2608-2615
8. Ristich V., Liang S., Zhang W., Wu J., and Horuzsko A. Tolerization of dendritic cells by HLA-G. Eur J Immunol 35 (2005) 1133-1142
9. Liang S., Ristich V., Arase H., Dausset J., Carosella E.D., and Horuzsko A. Modulation of dendritic cell differentiation by HLA-G and ILT4 requires the IL-6--STAT3 signaling pathway. Proc Natl Acad Sci U S A 105 (2008) 8357-8362
10. Park B., Lee S., Kim E., Chang S., Jin M., and Ahn K. The truncated cytoplasmic tail of HLA-G serves a quality-control function in post-ER compartments. Immunity 15 (2001) 213-224
11. McMaster M.T., Librach C.L., Zhou Y., et al. Human placental HLA-G expression is restricted to differentiated cytotrophoblasts. J Immunol 154 (1995) 3771-3778
12. Amiot L., Onno M., Renard I., et al. HLA-G transcription studies during the different stages of normal and malignant hematopoiesis. Tissue Antigens 48 (1996) 609-614
13. Menier C., Rabreau M., Challier J.C., Le Discorde M., Carosella E.D., and Rouas-Freiss N. Erythroblasts secrete the nonclassical HLA-G molecule from primitive to definitive hematopoiesis. Blood 104 (2004) 3153-3160
14. Mallet V., Fournel S., Schmitt C., Campan A., Lenfant F., and Le Bouteiller P. Primary cultured human thymic epithelial cells express both membrane-bound and soluble HLA-G translated products. J Reprod Immunol 43 (1999) 225-234
15. Le Discorde M., Moreau P., Sabatier P., Legeais J.M., and Carosella E.D. Expression of HLA-G in human cornea, an immune-privileged tissue. Hum Immunol 64 (2003) 1039-1044
16. Lila N., Amrein C., Guillemain R., et al. Human leukocyte antigen-G expression after heart transplantation is associated with a reduced incidence of rejection. Circulation 105 (2002) 1949-1954
17. Lila N., Carpentier A., Amrein C., Khalil-Daher I., Dausset J., and Carosella E.D. Implication of HLA-G molecule in heart-graft acceptance. Lancet 355 (2000) 2138
18. Creput C., Durrbach A., Menier C., et al. Human leukocyte antigen-G (HLA-G) expression in biliary epithelial cells is associated with allograft acceptance in liver-kidney transplantation. J Hepatol 39 (2003) 587-594
19. Creput C., Le Friec G., Bahri R., et al. Detection of HLA-G in serum and graft biopsy associated with fewer acute rejections following combined liver-kidney transplantation: Possible implications for monitoring patients. Hum Immunol 64 (2003) 1033-1038
20. Crispim J.C., Duarte R.A., Soares C.P., et al. Human leukocyte antigen-G expression after kidney transplantation is associated with a reduced incidence of rejection. Transpl Immunol 18 (2008) 361-367
21. Racca A.L., Veaute C.M., Bailat A.S., et al. Expression of HLA-G and MICA mRNA in renal allograft. Transpl Immunol 21 (2009) 10-12
22. Luque J., Torres M.I., Aumente M.D., et al. Soluble HLA-G in heart transplantation: Their relationship to rejection episodes and immunosuppressive therapy. Hum Immunol 67 (2006) 257-263
23. Naji A., Le Rond S., Durrbach A., et al. CD3+CD4low and CD3+CD8low are induced by HLA-G: Novel human peripheral blood suppressor T-cell subsets involved in transplant acceptance. Blood 110 (2007) 3936-3948
24. Qiu J., Terasaki P.I., Miller J., Mizutani K., Cai J., and Carosella E.D. Soluble HLA-G expression and renal graft acceptance. Am J Transplant 6 (2006) 2152-2156
25. Lila N., Rouas-Freiss N., Dausset J., Carpentier A., and Carosella E.D. Soluble HLA-G protein secreted by allospecific CD4+ T cells suppresses the alloproliferative response: A CD4+ T cell regulatory mechanism. Proc Natl Acad Sci U S A 98 (2001) 12150-12155
26. Park G.M., Lee S., Park B., et al. Soluble HLA-G generated by proteolytic shedding inhibits NK-mediated cell lysis. Biochem Biophys Res Commun 313 (2004) 606-611
27. Solier C., Aguerre-Girr M., Lenfant F., et al. Secretion of pro-apoptotic intron 4-retaining soluble HLA-G1 by human villous trophoblast. Eur J Immunol 32 (2002) 3576-3586
28. Naji A., Durrbach A., Carosella E.D., and Rouas-Freiss N. Soluble HLA-G and HLA-G1 expressing antigen-presenting cells inhibit T-cell alloproliferation through ILT-2/ILT-4/FasL-mediated pathways. Hum Immunol 68 (2007) 233-239
29. Gros F., Cabillic F., Toutirais O., Maux A.L., Sebti Y., and Amiot L. Soluble HLA-G molecules impair natural killer/dendritic cell crosstalk via inhibition of dendritic cells. Eur J Immunol 38 (2008) 742-749
30. Zavazava N., and Kronke M. Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes. Nat Med 2 (1996) 1005-1010
31. Spaggiari G.M., Contini P., Carosio R., et al. Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8: Evidence for a negative regulation exerted by members of the inhibitory receptor superfamily. Blood 99 (2002) 1706-1714
32. Contini P., Ghio M., Poggi A., et al. Soluble HLA-A, -B, -C and -G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation. Eur J Immunol 33 (2003) 125-134
33. Contini P., Ghio M., Merlo A., et al. Soluble HLA class I/CD8 ligation triggers apoptosis in EBV-specific CD8+ cytotoxic T lymphocytes by Fas/Fas-ligand interaction. Hum Immunol 61 (2000) 1347-1351
34. Shiroishi M., Tsumoto K., Amano K., et al. Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc Natl Acad Sci U S A 100 (2003) 8856-8861
35. Schutt P., Rebmann V., Brandhorst D., et al. The clinical significance of soluble human leukocyte antigen class-I, ICTP, and RANKL molecules in multiple myeloma patients. Hum Immunol 69 (2008) 79-87
36. Rebmann V., Lemaoult J., Rouas-Freiss N., Carosella E.D., and Grosse-Wilde H. Report of the Wet Workshop for Quantification of Soluble HLA-G in Essen, 2004. Hum Immunol 66 (2005) 853-863
37. Rebmann V., Pfeiffer K., Passler M., et al. Detection of soluble HLA-G molecules in plasma and amniotic fluid. Tissue Antigens 53 (1999) 14-22
38. Spaggiari G.M., Contini P., Dondero A., et al. Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction. Blood 100 (2002) 4098-4107
39. Rebmann V., van der Ven K., Passler M., Pfeiffer K., Krebs D., and Grosse-Wilde H. Association of soluble HLA-G plasma levels with HLA-G alleles. Tissue Antigens 57 (2001) 15-21
40. Luque J., Torres M.I., Aumente M.D., et al. sHLA-G levels in the monitoring of immunosuppressive therapy and rejection following heart transplantation. Transpl Immunol 17 (2006) 70-73
41. Puppo F., Contini P., Ghio M., et al. Soluble human MHC class I molecules induce soluble Fas ligand secretion and trigger apoptosis in activated CD8(+) Fas (CD95)(+) T lymphocytes. Int Immunol 12 (2000) 195-203
42. LeMaoult J., Krawice-Radanne I., Dausset J., and Carosella E.D. HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4+ T cells. Proc Natl Acad Sci U S A 101 (2004) 7064-7069
43. Kanai T., Fujii T., Kozuma S., et al. Soluble HLA-G influences the release of cytokines from allogeneic peripheral blood mononuclear cells in culture. Mol Hum Reprod 7 (2001) 195-200
44. Clements C.S., Kjer-Nielsen L., McCluskey J., and Rossjohn J. Structural studies on HLA-G: Implications for ligand and receptor binding. Hum Immunol 68 (2007) 220-226
45. Shiroishi M., Kuroki K., Rasubala L., et al. Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d). Proc Natl Acad Sci U S A 103 (2006) 16412-16417
46. Shiroishi M., Kuroki K., Ose T., et al. Efficient leukocyte Ig-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer. J Biol Chem 281 (2006) 10439-10447
47. Shiroishi M., Kohda D., and Maenaka K. Preparation and crystallization of the disulfide-linked HLA-G dimer. Biochim Biophys Acta 1764 (2006) 985-988
48. Boyson J.E., Erskine R., Whitman M.C., et al. Disulfide bond-mediated dimerization of HLA-G on the cell surface. Proc Natl Acad Sci U S A 99 (2002) 16180-16185
49. Zhong M., Weng X., Liang Z., et al. Dimerization of soluble HLA-G by IgG-Fc fragment augments ILT2-mediated inhibition of T-cell alloresponse. Transplantation 87 (2009) 8-15
50. LeMaoult J., Zafaranloo K., Le Danff C., and Carosella E.D. HLA-G upregulates ILT2, ILT3, ILT4, and KIR2DL4 in antigen presenting cells, NK cells, and T cells. FASEB J 19 (2005) 662-664