Cytokine gene expression in splenic CD4+ and CD8+ T cell subsets of genetically resistant and susceptible chickens infected with Marek's disease virus

Veterinary Immunology and Immunopathology

Volumn 132, Issue 2-4, 2009, Pages 209-217

  Parvizi, P ^a   Read, L R ^a   Abdul Careem, M F ^a   Sarson, A J ^a   Lusty, C ^a   Lambourne, M ^a   Thanthrige Don, N ^a   Burgess, S C ^b   Sharif, S ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b MISSISSIPPI STATE UNIVERSITY   (United States)

Author keywords

CD4 T cell; CD8 T cell; Chicken; Cytokine; Disease resistance; Immunology; Marek's disease; Real time qRT PCR

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN B; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIRD DISEASE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHICKEN; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOMODULATION; INFECTION RESISTANCE; INFECTION SENSITIVITY; MARDIVIRUS; NONHUMAN; T LYMPHOCYTE SUBPOPULATION; VIRUS IMMUNITY;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHICKENS; CYTOKINES; GENE EXPRESSION; GENES, VIRAL; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-18; INTERLEUKIN-4; INTERLEUKIN-6; MARDIVIRUS; MAREK DISEASE; SPECIES SPECIFICITY; TIME FACTORS;

GALLID HERPESVIRUS 2; GALLUS GALLUS;

EID: 70449523556     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2009.06.009     Document Type: Article

References (50)

1. Abdul-Careem M.F., Hunter B.D., Nagy E., Read L.R., Sanei B., Spencer J.L., and Sharif S. Development of a real-time PCR assay using SYBR green chemistry for monitoring Marek's disease virus genome load in feather tips. J. Virol. Methods 133 (2006) 34-40
2. Abdul-Careem M.F., Hunter B.D., Parvizi P., Haghighi H.R., Thanthrige-Don N., and Sharif S. Cytokine gene expression patterns associated with immunization against Marek's disease in chickens. Vaccine 25 (2007) 424-432
3. Abdul-Careem M.F., Hunter B.D., Sarson A.J., Parvizi P., Haghighi H.R., Read L., et al. Host responses are induced in feathers of chickens infected with Marek's disease virus. Virology 370 (2008) 323-332
4. Bacon L.D., Hunt H.D., and Cheng H.H. Genetic resistance to Marek's disease. In: Hirai K. (Ed). Marek's Disease (2001), Springer-Verlag, Berlin, Heidelberg, New York 121-141
5. Belkaid Y., Piccirillo C.A., Mendez S., Shevach E.M., and Sacks D.L. CD4+ CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420 (2002) 502-507
6. Berndt A., Pieper J., and Methner U. Circulating gamma delta T cells in response to Salmonella enterica serovar Enteritidis exposure in chickens. Infect. Immun. 74 (2006) 3967-3978
7. Briles W.E., and Briles R.W. Identification of haplotypes of the chicken major histocompatibility complex (B). Immunogenetics 15 (1982) 449-459
8. Buza J.J., and Burgess S.C. Modeling the proteome of a Marek's disease transformed cell line: a natural animal model for CD30 overexpressing lymphomas. Proteomics 7 (2007) 1316-1326
9. Calnek B.W. Pathogenesis of Marek's disease virus infection. In: Hirai K. (Ed). Marek's Disease (2001), Springer-Verlag, Berlin, Heidelberg, New York 25-55
10. Calnek B.W. Marek's disease-a model for herpesvirus oncology. Crit. Rev. Microbiol. 12 (1986) 293-320
11. Calnek B.W., and Madin S.H. Characteristics of in vitro infection of chicken kidney cell cultures with a herpesvirus from Marek's disease. Am. J. Vet. Res. 30 (1969) 1389-1402
12. Chan M.M., Chen C.L., Ager L.L., and Cooper M.D. Identification of the avian homologues of mammalian CD4 and CD8 antigens. J. Immunol. 140 (1988) 2133-2138
13. Cole R.K. Studies on genetic resistance to Marek's disease. Avian Diseases (1967) 9-29
14. Davison A. Comments on the phylogenetics and evolution of herpesviruses and other large DNA viruses. Virus Res. 82 (2002) 127-132
15. Degen W.G., Daal N., Rothwell L., Kaiser P., and Schijns V.E. Th1/Th2 polarization by viral and helminth infection in birds. Vet. Microbiol. 105 (2005) 163-167
16. Djeraba A., Musset E., Bernardet N., Le Vern Y., and Quere P. Similar pattern of iNOS expression, NO production and cytokine response in genetic and vaccination-acquired resistance to Marek's disease. Vet. Immunol. Immunopathol. 85 (2002) 63-75
17. Giansanti F., Giardi M.F., and Botti D. Avian cytokines-an overview. Curr. Pharm. Des. 12 (2006) 3083-3099
18. Gobel T.W., Schneider K., Schaerer B., Mejri I., Puehler F., Weigend S., et al. IL-18 stimulates the proliferation and IFN-gamma release of CD4+ T cells in the chicken: Conservation of a Th1-like system in a nonmammalian species. J. Immunol. 171 (2003) 1809-1815
19. Heidari M., Zhang H.M., and Sharif S. Marek's disease virus induces th-2 activity during cytolytic infection. Viral Immunol. (2008)
20. Hong Y.H., Lillehoj H.S., Lillehoj E.P., and Lee S.H. Changes in immune-related gene expression and intestinal lymphocyte subpopulations following eimeria maxima infection of chickens. Vet. Immunol. Immunopathol. 114 (2006) 259-272
21. Izumiya Y., Jang H.-K., Ono M., and Mikami T. A complete genomic DNA sequence of Marek's disease virus type 2, strain HPRS24. In: Hirai K. (Ed). Marek's Disease (2001), Springer-Verlag, Berlin, Heidelberg, New York
22. Jarosinski K.W., Njaa B.L., O'connell P.H., and Schat K.A. Pro-inflammatory responses in chicken spleen and brain tissues after infection with very virulent plus Marek's disease virus. Viral Immunol. 18 (2005) 148-161
23. Jarosinski K.W., Yunis R., O'Connell P.H., Markowski-Grimsrud C.J., and Schat K.A. Influence of genetic resistance of the chicken and virulence of Marek's disease virus (MDV) on nitric oxide responses after MDV infection. Avian Dis. 46 (2002) 636-649
24. Kaiser P., Underwood G., and Davison F. Differential cytokine responses following Marek's disease virus infection of chickens differing in resistance to Marek's disease. J. Virol. 77 (2003) 762-768
25. Lee S.I., Ohashi K., Morimura T., Sugimoto C., and Onuma M. Re-isolation of Marek's disease virus from T cell subsets of vaccinated and non-vaccinated chickens. Arch. Virol. 144 (1999) 45-54
26. Lessard M., Hutchings D.L., Spencer J.L., Lillehoj H.S., and Gavora J.S. Influence of Marek's disease virus strain AC-1 on cellular immunity in birds carrying endogenous viral genes. Avian Dis. 40 (1996) 645-653
27. Lillehoj H.S., Lillehoj E.P., Weinstock D., and Schat K.A. Functional and biochemical characterizations of avian T lymphocyte antigens identified by monoclonal antibodies. Eur. J. Immunol. 18 (1988) 2059-2065
28. Longenecker B.M., Pazderka F., Gavora J.S., Spencer J.L., and Ruth R.F. Lymphoma induced by herpesvirus: resistance associated with a major histocompatibility gene. Immunogenetics 3 (1976) 401-407
29. Lynagh G.R., Bailey M., and Kaiser P. Interleukin-6 is produced during both murine and avian eimeria infections. Vet. Immunol. Immunopathol. 76 (2000) 89-102
30. Markowski-Grimsrud C.J., and Schat K.A. Cytotoxic T lymphocyte responses to Marek's disease herpesvirus-encoded glycoproteins. Vet. Immunol. Immunopathol. 90 (2002) 133-144
31. Minang J.T., Arestrom I., Zuber B., Jonsson G., Troye-Blomberg M., and Ahlborg N. Nickel-induced IL-10 down-regulates Th1- but not Th2-type cytokine responses to the contact allergen nickel. Clin. Exp. Immunol. 143 (2006) 494-502
32. Murphy K.M., and Reiner S.L. The lineage decisions of helper T cells. Nat. Rev. Immunol. 2 (2002) 933-944
33. Nair V., and Kung H.J. Marek's disease virus oncogenecity: molecular mechanisms. In: Davison F., and Nair V. (Eds). Marek's Disease: An Evolving Problem (2004), Elsevier, Great Britain 32-47
34. Okada T., Takagi M., Murata S., Onuma M., and Ohashi K. Identification and characterization of a novel spliced form of the meq transcript in lymphoblastoid cell lines derived from Marek's disease tumours. J. Gen. Virol. 88 (2007) 2111-2120
35. Okamura H., Tsutsi H., Komatsu T., Yutsudo M., Hakura A., Tanimoto T., et al. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature 378 (1995) 88-91
36. Parvizi P., Read L., Abdul-Careem M.F., Lusty C., and Sharif S. Cytokine gene expression in splenic CD4(+) and CD8(+) T-cell subsets of chickens infected with Marek's disease virus. Viral Immunol. 22 1 (2009 Feb) 31-38
37. Pazderka F., Longenecker B.M., Law G.R.J., Stone H.A., and Ruth R.F. Histocompatibility of chicken populations selected for resistance to Marek's disease. Immunogenetics 2 (1975) 93-100
38. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29 (2001) e45
39. Pfaffl M.W., Horgan G.W., and Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 30 (2002) e36
40. Quere P., Rivas C., Ester K., Novak R., and Ragland W.L. Abundance of IFN-alpha and IFN-gamma mRNA in blood of resistant and susceptible chickens infected with Marek's disease virus (MDV) or vaccinated with turkey herpesvirus; and MDV inhibition of subsequent induction of IFN gene transcription. Arch. Virol. 150 (2005) 507-519
41. Rothwell L., Young J.R., Zoorob R., Whittaker C.A., Hesketh P., Archer A., et al. Cloning and characterization of chicken IL-10 and its role in the immune response to eimeria maxima. J. Immunol. 173 (2004) 2675-2682
42. Schat K.A., Chen C.L., Calnek B.W., and Char D. Transformation of T-lymphocyte subsets by Marek's disease herpesvirus. J. Virol. 65 (1991) 1408-1413
43. Schat K.A., Chen C.L., Shek W.R., and Calnek B.W. Surface antigens on Marek's disease lymphoblastoid tumor cell lines. J. Natl. Cancer Inst. 69 (1982) 715-720
44. Shack L.A., Buza J.J., and Burgess S.C. The neoplastically transformed (CD30(hi)) Marek's disease lymphoma cell phenotype most closely resembles T-regulatory cells. Cancer Immunol. Immunother. 57 (2008) 1253-1262
45. Sloan D.D., and Jerome K.R. Herpes simplex virus remodels T-cell receptor signaling, resulting in p38-dependent selective synthesis of interleukin-10. J. Virol. 81 (2007) 12504-12514
46. Stober C.B., Lange U.G., Roberts M.T., Alcami A., and Blackwell J.M. IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection. J. Immunol. 175 (2005) 2517-2524
47. Wigley P., and Kaiser P. Avian cytokines in health and disease. Braz. J. Poultry Sci. 5 (2003) 1-14
48. Xing Z., and Schat K.A. Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus. J. Virol. 74 (2000) 3605-3612
49. Xing Z., and Schat K.A. Expression of cytokine genes in Marek's disease virus-infected chickens and chicken embryo fibroblast cultures. Immunology 100 (2000) 70-76
50. Xu D., Trajkovic V., Hunter D., Leung B.P., Schulz K., Gracie J.A., et al. IL-18 induces the differentiation of Th1 or Th2 cells depending upon cytokine milieu and genetic background. Eur. J. Immunol. 30 (2000) 3147-3156