Myxinidin, a novel antimicrobial peptide from the epidermal mucus of hagfish, Myxine glutinosa L.

Marine Biotechnology

Volumn 11, Issue 6, 2009, Pages 748-757

  Subramanian, Sangeetha ^a,b   Ross, Neil W ^a   MacKinnon, Shawna L ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Antimicrobial peptide; Hagfish; Innate immunity; Mucus; Myxinidin

Indexed keywords

ANTIMICROBIAL PEPTIDE; HAGFISH; INNATE IMMUNITY; MUCUS; MYXINIDIN;

AMINES; AMINO ACIDS; BIOASSAY; BLOOD; ESCHERICHIA COLI; MAMMALS; MASS SPECTROMETRY; MEATS; ORGANIC ACIDS; PATHOGENS; PEPTIDES; SODIUM; SODIUM CHLORIDE; YEAST;

POLYPEPTIDES;

ANTIINFECTIVE AGENT; PEPTIDE;

AMINO ACID; ANTIMICROBIAL ACTIVITY; DEFENSE BEHAVIOR; FISH; HOST-PATHOGEN INTERACTION; IMMUNITY; INFECTIOUS DISEASE; INNATE BEHAVIOR; MAMMAL; MASS SPECTROMETRY; MUCUS; PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BACTERIUM; CHEMISTRY; DRUG EFFECT; EPIDERMIS; FRACTIONATION; HAGFISH; IMMUNOLOGY; INNATE IMMUNITY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; MICROBIOLOGICAL EXAMINATION; MOLECULAR GENETICS; MUCUS; SEQUENCE ANALYSIS; YEAST;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; BACTERIA; CHEMICAL FRACTIONATION; EPIDERMIS; HAGFISHES; IMMUNITY, INNATE; MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUCUS; PEPTIDES; SEQUENCE ANALYSIS, PROTEIN; YEASTS;

AEROMONAS SALMONICIDA; BACTERIA (MICROORGANISMS); CANDIDA ALBICANS; ESCHERICHIA COLI; HAGFISH; LISTONELLA ANGUILLARUM; MAMMALIA; MYXINE GLUTINOSA; SALMONELLA ENTERICA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; STAPHYLOCOCCUS EPIDERMIDIS; YERSINIA RUCKERI;

EID: 70449523332     PISSN: 14362228     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10126-009-9189-y     Document Type: Article

References (56)

1. Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402.
2. Aranishi F, Mano N (2000) Response of skin cathepsins to infection of Edwardsiella tarda in Japanese flounder. Fish Sci 66:169-170.
3. Argiolas A, Pisano JJ (1985) Bombolitins, a new class of mast cell degranulating peptides from the venom of the bumblebee (Megabombus pennsylvanicus). J Biol Chem 260:1437-1444.
4. Austin B, McIntosh D (1988) Natural antibacterial compounds on the surface of rainbow trout, Salmo gairdneri Richardson. J Fish Dis 11:275-277.
5. Bardack D (1998) Relationships of living and fossil hagfishes. In: Jorgensen JM, Lomholt JP, Weber RE, Malte H (eds) The Biology of Hagfishes. Chapman and Hall, London, U.K., pp 3-14.
6. Befus AD, Mowat C, Gilchrist M, Hu J, Solomon S, Bateman A (1999) Neutrophil defensins induce histamine secretion from mast cells: mechanisms of action. J Immunol 163:947-953.
7. Bergsson G, Agerberth B, Jörnvall H, Gudmundsson GH (2005) Isolation and identification of antimicrobial components from the epidermal mucus of Atlantic cod (Gadus morhua). FEBS J 272:4960-4969.
8. Bignami GS (1993) A rapid and sensitive hemolysis neutralization assay for palytoxin. Toxicon 31:817-820.
9. Birkemo GA, Luders T, Anderson O, Nes IF, Nissen-Meyyer J (2003) Hipposin, a histone-derived antimicrobial peptide in Atlantic halibut (Hippoglossus hippoglossus L.). Biochim Biophys Acta 1646:207-215.
10. Blum H, Beier H, Gross HJ (1987) Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels. Electrophoresis 8:93-99.
11. Boman HG, Nilsson-Faye I, Paul K, Rasmuson T Jr (1974) Characteristics of an inducible cell-free antibacterial reaction in hemolymph of Samia Cynthia pupae. Infect Immun 10:136-145.
12. Boulanger N, Munks RJL, Hamilton JV, Vovelle F, Brun R, Lehane MJ, Bulet P (2002) A novel antimicoribal peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans. J Biol Chem 277:49921-49926.
13. Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of proteins using the principle of protein-dye binding. Anal Biochem 72:248-254.
14. Brogden KA (2005) Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev 3:238-250.
15. Cole AM, Weis P, Diamond G (1997) Isolation and characterization of pleurocidin, an antimicrobial peptides in the skin secretions of winter flounder. J Biol Chem 272:12008-12013.
16. Ellis AE (2001) Innate host defense mechanisms of fish against viruses and bacteria. Dev Comp Immunol 25:827-839.
17. Fernandes JMO, Molle G, Kemp GD, Smith VJ (2004) Isolation and characterization of Oncorhyncin II, a histone H1-derived antimicrobial peptide from skin secretions of rainbow trout, Oncorhynchus mykiss. Dev Comp Immunol 28:127-138.
18. Fernandes JMO, Saint N, Kemp GD, Smith VJ (2003) Oncorhyncin III: a potent antimicrobial peptide derived from the non-histone chromosomal protein H6 of rainbow trout, Oncorhynchus mykiss. Biochem J 373:621-628.
19. Fields PI, Groisman EA, Heffron F (1989) A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cells. Science 243:1059-1062.
20. Fouz B, Devesa S, Gravningen K, Barja JL, Toranzo AE (1990) Antibacterial action of the mucus of turbot. Bull Eur Assoc Fish Pathol 10:56-59.
21. Goldman MJ, Anderson GM, Stolzenberg ED, Kari UP, Zasloff M, Wilson JM (1997) Human β-defensin-1 is a salt-sensitive antibiotic in ling that is inactivated in cystic fibrosis. Cell 88:553-560.
22. Habermann E (1972) Bee and wasp venoms. Science 177:314-322.
23. Hancock REW (1997) Peptide antibiotics. Lancet 349:418-422.
24. Hancock REW (2001) Cationic peptides: effectors in innate immunity and novel antimicrobials. Lancet Infect Dis 1:156-164.
25. Hwang EY, Seo JK, Kim CH, Go HJ, Kim EJ, Chung JK, Ryu HS, Park NG (1999) Purification and characterization of a novel antimicrobial peptide from the skin of the hagfish, Eptatretus burgeri. J Food Sci 4:28-32.
26. Kanno T, Nakai T, Muroga K (1989) Mode of transmission of vibriosis among ayu, Plecoglossus altivelis. J Aquat Anim Health 1:2-6.
27. Kennedy J, Baker P, Piper C, Cotter PD, Walsh M, Mooij MJ, Bourke MB, Rea MC, O'Connor PM, Ross RP, Hill C, O'Gara F, Marchesi JR, Dobson ADW (2008) Isolation and analysis of bacteria with antimicrobial activitites from marine sponge Haliclona simulans collected from Irish waters. Mar Biotechnol. doi:10.1007/s10126-008-9154-1.
28. Kimbrell DA, Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2:256-267.
29. Kjuul AK, Büllesbach EE, Espelid S, Dunham R, Jørgensen TØ, Warr GW, Styrvold OB (1999) Effects of cecropin peptides on bacteria pathogenic to fish. J Fish Dis 22:387-394.
30. Lazarovici P, Primor N, Loew LM (1986) Purification and pore-forming activity of two hydrophobic polypeptides from the secretion of the Red Sea Moses sole (Pardachirus marmoratus). J Biol Chem 261:16704-16713.
31. Lemaître C, Orange N, Saglio P, Saint N, Gagnon J, Molle G (1996) Characterization and ion channel activities of novel antibacterial proteins from the skin mucosa of carp (Cyprinus carpio). Eur J Biochem 240:143-149.
32. Lüders T, Birkemo GA, Meyer JN, Andersen Ø, Nes IF (2005) Proline conformation-dependent antimicrobial activity of a proline-rich histone H1 N-terminal peptide fragment isolated from the skin mucus of Atlantic salmon. Antimicrob Agents Chemother 49:2399-2406.
33. Ming L, Xiaoling P, Yan L, Lili W, Qi W, Xiyong Y, Boyao W, Ning H (2007) Purification of antimicrobial factors from human cervical mucus. Hum Reprod 22:1810-1815.
34. Nagashima Y, Kikuchi N, Shimakura K, Shiomi K (2003) Purification and characterization of an antibacterial factor in the skin secretion of rock fish Sebastes schlegeli. Comp Biochem Physiol 136C:63-71.
35. Noga EJ, Silphaduang U (2003) Piscidins: a novel family of peptide antibiotics from fish. Drug News Perspect 16:87-92.
36. Oren Z, Shai Y (1996) A class of highly potent antibacterial peptides derived from pardaxin, a pore-forming peptide isolated from Moses sole Pardachirus marmoratus. Eur J Biochem 237:303-310.
37. Palakaha KJ, Shin GW, Kim YR, Jung TS (2008) Evaluation of non-specific immune components from the skin mucus of olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol 24:479-488.
38. Park IY, Park CB, Kim MS, Kim SC (1998) Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS Lett 437:258-262.
39. Patrzykat A, Friedrich CL, Zhang L, Mendoza V, Hancock REW (2002) Sublethal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in Escherichia coli. Antimicrob Agents Chemother 46:605-614.
40. Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE (2003) Novel antimicrobial peptides derived from flatfish genes. Antimicrob Agents Chemother 47:2464-2470.
41. Patrzykat A, Zhang L, Mendoza V, Iwama GK, Hancock REW (2001) Synergy of histone-derived peptides of coho salmon with lysozyme and flounder pleurocidin. Antimicrob Agents Chemother 45:1337-1342.
42. Pukala TL, Bowie JH, Maselli VM, Musgrave IF, Tyler MJ (2006) Host-defence peptides from the glandular secretions of amphibians: structure and activity. Nat Prod Rep 23:368-393.
43. Raison RL, dos Remedios NJ (1998) The hagfish immune system. In: Jorgensen JM, Lomholt JP, Weber RE, Malte H (eds) The Biology of Hagfishes. U.K.:Chapman and Hall, London, pp 334-344.
44. Robinson WE Jr, McDougall B, Tran D, Selsted ME (1998) Anti-HIV-1 activity of indolicidin, an antimicrobial peptide from neutrophils. J Leukoc Biol 63:94-100.
45. Rolff J (2007) Why did the acquired immune system of vertebrates evolve? Dev Comp Immunol 31:476-482.
46. Sarmaşik A (2002) Antimicrobial peptides: a potential therapeutic alternative for the treatment of fish diseases. Turk J Biol 26:201-207.
47. Schägger H, Jagow GV (1987) Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 166:368-379.
48. Scott MG, Rosenberger CM, Gold MR, Finlay BB, Hancock REW (2000) An α-helical cationic antimicrobial peptide selectively modulates macrophage responses to lipopolysaccharide and directly alters macrophage gene expression. J Immunol 165:3358-3365.
49. Shephard KL (1993) Mucus on the epidermis of fish and its influence on drug delivery. Adv Drug Deliv Rev 11:403-417.
50. Shinnar AE, Uzzell T, Rao MN, Spooner E, Lane WS, Zasloff M (1996) New family of linear antimicrobial peptides from hagfish intestine contains bromotryptophan as novel amino acid. In: Kaumaya PTP, Hodges RS (eds) Proceedings of the fourteenth American peptide symposium. U.S.A. Mayflower Scientific Ltd., Ohio, pp 189-191.
51. Subramanian S, MacKinnon SL, Ross NW (2007) A comparative study on innate immune parameters in the epidermal mucus of various fish species. Comp Biochem Physiol 148B:256-263.
52. Subramanian S, Ross NW, MacKinnon SL (2008) Comparison of antimicrobial activity in the epidermal mucus extracts of fish. Comp Biochem Physiol 150B:85-92.
53. Syvitski R, Burton I, Mattatall NR, Douglas SE, Jakeman DL (2005) Structural characterization of the antimicrobial peptide pleurocidin from winter flounder. Biochemistry 44:7282-7293.
54. Verbanac D, Zanetti M, Romeo D (1993) Chemotactic and protease-inhibiting activities of antibiotic peptide precursors. FEBS Lett 317:255-258.
55. Wang Z, Wang G (2004) APD: the antimicrobial peptide database. Nucleic Acids Res 32:590-592.
56. Yano T (1996) The non-specific immune system: humoral defence. In: Iwama G, Nakanishi T (eds) The fish Immune system: Organism, Pathogen and Environment. Academic press, San Diego, U.S.A, pp 105-157.