Screening for germline mutations of MLH1, MSH2, MSH6 and PMS2 genes in Slovenian colorectal cancer patients: Implications for a population specific detection strategy of Lynch syndrome

Familial Cancer

Volumn 8, Issue 4, 2009, Pages 421-429

  Berginc, Gašper ^a   Bračko, Matej ^b   Ravnik Glavač, Metka ^a   Glavač, Damjan ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b INSTITUTE OF ONCOLOGY   (Slovenia)

Author keywords

Detection strategy; Lynch syndrome; Microsatellite instability; Mismatch repair genes; Mononucleotide microsatellite markers

Indexed keywords

MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; COLORECTAL CANCER; FAMILIAL CANCER; FEMALE; GENE FUNCTION; GENE REARRANGEMENT; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; METHYLATION; MICROSATELLITE INSTABILITY; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; SLOVENIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; AGED; BASE SEQUENCE; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA METHYLATION; DNA MISMATCH REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GERM-LINE MUTATION; HUMANS; MALE; MICROSATELLITE INSTABILITY; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; SLOVENIA; TUMOR MARKERS, BIOLOGICAL;

EID: 70449521186     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10689-009-9258-4     Document Type: Article

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