Protective effect of copy number polymorphism of glutathione S-transferase T1 gene on melanoma risk in presence of CDKN2A mutations, MC1R variants and host-related phenotypes

Familial Cancer

Volumn 8, Issue 4, 2009, Pages 371-377

  Chaudru, Valérie ^a,b   Lo, M T ^a,c   Lesueur, F ^d,e   Marian, C ^f   Mohamdi, H ^a,c   Laud, K ^g   Barrois, M ^d   Chompret, A ^d   Avril, M F ^h   Demenais, F ^a,c   Paillerets, B Bressac De ^d  

^a FONDATION JEAN DAUSSET CEPH   (France)

^b UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d INSTITUT GUSTAVE ROUSSY   (France)

^e INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^f GEORGETOWN UNIVERSITY   (United States)

^g INSTITUT CURIE   (France)

^h Université René Descartes Paris 5 ^*  (France)

Author keywords

CDKN2A mutations; GSTM1; GSTP1; GSTT1; MC1R variants; Melanoma

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1;

ADULT; ARTICLE; CANCER RISK; CORRELATION ANALYSIS; FAMILIAL CANCER; FEMALE; GENE; GENE FUNCTION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; MC1R GENE; MELANOMA; NULL ALLELE; PENETRANCE; PHENOTYPE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SUN EXPOSURE;

ADULT; DNA COPY NUMBER VARIATIONS; FEMALE; GENES, P16; GENETIC PREDISPOSITION TO DISEASE; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; MALE; MELANOMA; MUTATION; PHENOTYPE; POLYMERASE CHAIN REACTION; RECEPTOR, MELANOCORTIN, TYPE 1; RISK FACTORS;

EID: 70449518191     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10689-009-9249-5     Document Type: Article

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