Human platelet alloantigens (HPA) 1, HPA2, HPA3, HPA4, and HPA5 polymorphisms in sickle cell anemia patients with vaso-occlusive crisis

European Journal of Haematology

Volumn 83, Issue 6, 2009, Pages 579-585

  Al Subaie, Abeer M ^a   Fawaz, Naglaa A ^b   Mahdi, Najat ^a,c   Al Absi, Iman K ^a   Al Ola, Khadija ^c   Ameen, Ghada ^a   Almawi, Wassim Y ^a  

^a ARABIAN GULF UNIVERSITY   (Bahrain)

^b SULTAN QABOOS UNIVERSITY HOSPITAL   (Oman)

^c Salmaniya Medical Complex ^*  (Bahrain)

Author keywords

Human platelet alloantigen; Sickle cell anemia; Vaso occlusive crisis

Indexed keywords

ALLOANTIGEN; FOLIC ACID; GENOMIC DNA; HEMOGLOBIN; HUMAN PLATELET ALLOANTIGEN 1; HUMAN PLATELET ALLOANTIGEN 2; HUMAN PLATELET ALLOANTIGEN 3; HUMAN PLATELET ALLOANTIGEN 4; HUMAN PLATELET ALLOANTIGEN 5; HYDROXYUREA; NARCOTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; ACUTE CHEST SYNDROME; ADOLESCENT; ALLELE; ARTICLE; AVASCULAR NECROSIS; BACKACHE; BLOOD SAMPLING; BLOOD TRANSFUSION; BLOOD VESSEL OCCLUSION; CASE CONTROL STUDY; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA EXTRACTION; DNA POLYMORPHISM; FEMALE; FEMUR HEAD; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HEMATOCRIT; HOSPITALIZATION; HUMAN; LEUKOCYTE COUNT; LIMB PAIN; MAJOR CLINICAL STUDY; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MULTIVARIATE ANALYSIS; ONSET AGE; OSTEOMYELITIS; PAIN ASSESSMENT; POLYMERASE CHAIN REACTION; PRIAPISM; PRIORITY JOURNAL; PROTHROMBIN TIME; RETROSPECTIVE STUDY; SICKLE CELL ANEMIA; STEADY STATE; THORAX PAIN; THROMBOCYTE COUNT; THROMBOPLASTIN TIME; UNIVARIATE ANALYSIS; VASOOCCLUSIVE CRISIS;

ACUTE CHEST SYNDROME; ANEMIA, SICKLE CELL; ANTIGENS, HUMAN PLATELET; ARTERIAL OCCLUSIVE DISEASES; BAHRAIN; CASE-CONTROL STUDIES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; PAIN; PLATELET ADHESIVENESS; POLYMORPHISM, GENETIC; RETROSPECTIVE STUDIES; RISK FACTORS; THROMBOSIS;

EID: 70449467284     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2009.01339.x     Document Type: Article

References (32)

1. Mehanna AS. Sickle cell anemia and antisickling agents then and now. Curr Med Chem 2001 8 : 79 88.
2. Conran N, Franco-Penteado CF, Costa FF. Newer aspects of the pathophysiology of sickle cell disease vaso-occlusion. Hemoglobin 2009 33 : 1 16.
3. Field JJ, Knight-Perry JE, Debaun MR. Acute pain in children and adults with sickle cell disease: management in the absence of evidence-based guidelines. Curr Opin Hematol 2009 16 : 173 178.
4. Zennadi R, Chien A, Xu K, Batchvarova M, Telen MJ. Sickle red cells induce adhesion of lymphocytes and monocytes to endothelium. Blood 2008 112 : 3474 3483.
5. Lanaro C, Franco-Penteado CF, Albuqueque DM, Saad ST, Conran N, Costa FF. Altered levels of cytokines and inflammatory mediators in plasma and leukocytes of sickle cell anemia patients and effects of hydroxyurea therapy. J Leukoc Biol 2009 85 : 235 242.
6. Kaul DK, Finnegan E, Barabino GA. Sickle red cell-endothelium interactions. Microcirculation 2009 16 : 97 111.
7. Buchanan GR, DeBaun MR, Quinn CT, Steinberg MH. Sickle Cell Disease. Hematology (Am Soc Hematol Educ Program) 2004 2004 (1 35 47.
8. Kutlar A, Kutlar F, Turker I, Tural C. The methylene tetrahydrofolate reductase (C667T) mutation as a potential risk factor for avascular necrosis in sickle cell disease. Hemoglobin 2001 25 : 213 217.
9. Sebastiani P, Ramoni MF, Nolan V, Baldwin CT, Steinberg MH. Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia. Nat Genet 2005 37 : 435 440.
10. Weyrich AS, Zimmerman GA. Platelets: signaling cells in the immune continuum. Trends Immunol 2004 25 : 489 495.
11. Santoso S. Human platelet alloantigens. Transfus Apher Sci 2003 28 : 227 236.
12. Rozman P. Platelet antigens. The role of human platelet alloantigens (HPA) in blood transfusion and transplantation. Transpl Immunol 2002 10 : 165 181.
13. Kunicki TJ. The influence of platelet collagen receptor polymorphisms in hemostasis and thrombotic disease. Arterioscler Thromb Vasc Biol 2002 22 : 14 20.
14. Deckmyn H, Ulrichts H, Van De Walle G, Vanhoorelbeke K. Platelet antigens and their function. Vox Sang 2004 87 (Suppl. 2 105 111.
15. Calvete JJ. Platelet integrin GPIIb/IIIa: structure-function correlations. An update and lessons from other integrins. Proc Soc Exp Biol Med 1999 222 : 29 38.
16. Corral J, Rivera J, González-Conejero R, Vicente V. The number of platelet glycoprotein Ia molecules is associated with the genetically linked 807 C/T and HPA-5 polymorphisms. Transfusion 1999 39 : 372 378.
17. Ulrichts H, Vanhoorelbeke K, Cauwenberghs S, Vauterin S, Kroll H, Santoso S, Deckmyn H. von Willebrand factor but not α-thrombin binding to platelet glycoprotein Ibα is influenced by the HPA-2 polymorphism. Arterioscler Thromb Vasc Biol 2003 23 : 1302 1307.
18. Bray PF. Platelet glycoprotein polymorphisms as risk factors for thrombosis. Curr Opin Hematol 2000 7 : 284 289.
19. Castro V, Alberto FL, Costa RN, Lepikson-Neto J, Gualandro SF, Figueiredo MS, Annichino-Bizzacchi JM, Saad ST, Costa F. Polymorphism of the human platelet antigen-5 system is a risk factor for occlusive vascular complications in patients with sickle cell anemia. Vox Sang 2004 87 : 118 123.
20. Baker RI, Eikelboom J, Lofthouse E, Staples N, Afshar-Kharghan V, López JA, Shen Y, Berndt MC, Hankey G. Platelet glycoprotein Iba Kozak polymorphism is associated with an increased risk of ischemic stroke. Blood 2001 98 : 36 40.
21. Iniesta JA, Gonzalez-Conejero R, Piqueras C, Vicente V, Corral J. Platelet GP IIIa polymorphism HPA-1 (PlA) protects against subarachnoid hemorrhage. Stroke 2004 35 : 2282 2286.
22. Gerhardt A, Scharf RE, Mikat-Drozdzynski B, Krussel JS, Bender HG, Zotz RB. The polymorphism of platelet membrane integrin α2β1 (α2807TT) is associated with premature onset of fetal loss. Thromb Haemost 2005 93 : 124 129.
23. Bojesen SE, Juul K, Schnohr P, Tybjaerg-Hansen A, Nordestgaard BG. Platelet glycoprotein IIb/IIIa Pl(A2)/Pl(A2) homozygosity associated with risk of ischemic cardiovascular disease and myocardial infarction in young men: the Copenhagen City Heart Study. J Am Coll Cardiol 2003 42 : 661 667.
24. Adams GT, Sneider H, McKie VC, Clair B, Brambilla D, Adams RJ, Kutlar F, Kutlar A. Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genome-wide screen. BMC Med Genet 2003 4 : 1 10.
25. Hurd CM, Cavanagh G, Schuh A, Ouwehand WH, Metcalfe P. Genotyping for platelet-specific antigens: techniques for the detection of single nucleotide polymorphisms. Vox Sang 2002 83 : 1 12.
26. Al-Subaie AM, Al-Absi IK, Al-Ola K, Saidi S, Fawaz NA, Almawi WY. Gene frequencies of human platelet alloantigens in Bahraini Arabs. Am J Hematol 2007 82 : 242 244.
27. Santoso S, Kunicki T. Platelet receptor polymorphisms and thrombotic risk. Ital Heart J 2001 2 : 811 815. (Pubitemid 34041370)
28. Kunicki TJ, Nugent DJ. The influence of platelet glycoprotein polymorphisms on receptor function and risk for thrombosis. Vox Sang 2002 83 (Suppl. 1 85 90.
29. Singer ST, Ataga KI. Hypercoagulability in sickle cell disease and beta-thalassemia. Curr Mol Med 2008 8 : 639 645.
30. Wun T, Cordoba M, Rangaswami A, Cheung AW, Paglieroni T. Activated monocytes and platelet-monocyte aggregates in patients with sickle cell disease. Clin Lab Haematol 2002 24 : 81 8.
31. Michelson AD, Furman MI, Goldschmidt-Clermont P, et al. Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists. Circulation 2000 101 : 1013 1018.
32. Charakida M, Tousoulis D, Stefanadis C, Toutouzas P. The impact of platelet glycoprotein IIIa and Ia polymorphisms in cardiovascular thrombotic disease. Ital Heart J 2003 4 : 17 22.