In-Source Fragmentation Technique for the Production of Thermalized Ions

Journal of the American Society for Mass Spectrometry

Volumn 20, Issue 12, 2009, Pages 2312-2317

  Carl, Damon R ^a   Moision, Robert M ^a   Armentrout, P B ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHARGE SEPARATIONS; COLLISION-INDUCED DISSOCIATION; CRITICAL SIZE; DISTRIBUTION OF IONS; ELECTRICAL COSTS; ENERGY PATHWAY; HEXAPOLE; HIGH PRESSURE REGIONS; ION FUNNELS; ION GUIDE; ION-BEAM MASS SPECTROMETER; LOWER ENERGIES; THERMALIZED IONS; WATER LOSS;

CALCIUM; ELECTROSPRAY IONIZATION; ION SOURCES; MASS SPECTROMETRY; SIZE SEPARATION;

IONS;

CALCIUM ION; WATER;

ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; ELECTRODE; ELECTROSPRAY MASS SPECTROMETRY; FRAGMENTATION REACTION; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; WATER LOSS;

HOT TEMPERATURE; IONS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 70449466828     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2009.08.024     Document Type: Article

References (20)

1. Loo J.A., Edmonds C.G., and Smith R.D. Primary Sequence Information from Intact Proteins by Electrospray Ionization Tandem Mass Spectrometry. Science 248 (1990) 201-204
2. Loo J.A., Edmonds C.G., and Smith R.D. Tandem Mass Spectrometry of Very Large Molecules: Serum Albumin Sequence Information from Multiply Charged Ions Formed by Electrospray Ionization. Anal. Chem. 63 (1991) 2488-2499
3. Zhai H., Han X., Breuker K., and McLafferty F.W. Consecutive Ion Activation for Top Down Mass Spectrometry: Improved Protein Sequencing by Nozzle-Skimmer Dissociation. Anal. Chem. 77 (2005) 5777-5784
4. Gauthier J.W., Trautman T.R., and Jacobson D.B. Sustained Off-Resonance Irradiation for Collision-Activated Dissociation Involving Fourier Transform Mass Spectrometry. Collision-Activated Dissociation Technique That Emulates Infrared Multiphoton Dissociation. Anal. Chim. Acta 246 (1991) 211-225
5. Little D.P., Speir J.P., Senko M.W., O'Connor P.B., and McLafferty F.W. Infrared Multiphoton Dissociation of Large Multiply-Charged Ions for Biomolecule Sequencing. Anal. Chem. 66 (1994) 2809-2815
6. Sannes-Lowery K., Griffey R.H., Kruppa G.H., Speir J.P., and Hofstadler S. Multipole Storage Assisted Dissociation, a Novel In-Source Dissociation Technique for Electrospray Ionization Generated Ions. Rapid Commun. Mass Spectrom. 12 (1998) 1957-1961
7. McFarland M.A., Hendrickson C.L., and Marshall A.G. Ion "Threshing": Collisionally Activated Dissociation in an External Octopole Ion Trap by Oscillation of an Axial Electric Potential Gradient. Anal. Chem. 76 (2004) 1545-1549
8. Hofstadler S.A., Sannes-Lowery K.A., and Griffey R.H. Infrared Multiphoton Dissociation in an External Ion Reservoir. Anal. Chem. 71 (1999) 2067-2070
9. Pan C., and Hettich R.L. Multipole-Storage-Assisted Dissociation for the Characterization of Large Proteins and Simple Protein Mixtures by ESI-FTICR-MS. Anal. Chem. 77 (2005) 3072-3082
10. Collings B.A., Stott W.R., and Londry F.A. Resonant Excitation in a Low-Pressure Linear Ion Trap. J. Am. Soc. Mass Spectrom. 14 (2003) 622-634
11. Campbell J.M., Collings B.A., and Douglas D.J. A New Linear Ion Trap Time-of-Flight System with Tandem Mass Spectrometry Capabilities. Rapid Commun. Mass Spectrom. 12 (1998) 1463-1474
12. Collings B.A. Increased Fragmentation Efficiency of Ions in a Low Pressure Linear Ion Trap with an Added dc Octopole Field. J. Am. Soc. Mass Spectrom. 16 (2005) 1342-1352
13. Vilkov A.N., Bogdanov B., Paša-Tolić L., Prior D.C., Anderson G.A., Masselson C.D., Moore R.J., and Smith R.D. Tailored noise waveform/collision-induced dissociation of ions stored in a linear ion trap combined with liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun. Mass Spectrom. 18 (2004) 2682-2690
14. Moision R.M., and Armentrout P.B. An Electrospray Ionization Source for Thermochemical Investigation with the Guided Ion Beam Mass Spectrometer. J. Am. Soc. Mass Spectrom. 18 (2007) 1124-1134
15. x complexes (x = 5-9). Int. J. Mass Spectrom. 265 (2007) 308-325
16. 2, HD) from thermal to 30 eV cm. J. Chem. Phys. 83 (1985) 166-189
17. Muntean F., and Armentrout P.B. Guided Ion Beam Study of Collision-Induced Dissociation Dynamics: Integral and Differential Cross Sections. J. Chem. Phys. 115 (2001) 1213-1228
18. Teloy E., and Gerlich D. Integral Cross Sections for Ion-Molecule Reactions. 1. The Guided Beam Technique. Chem. Phys. 4 (1974) 417-427
19. +. J. Am. Chem. Soc. 121 (1999) 1565-1573
20. x complexes (x = 2-8). J. Phys. Chem. A, unpublished (manuscript in preparation).