The differential effects of the timing of maternal nutrient restriction in the ovine placenta on glucocorticoid sensitivity, uncoupling protein 2, peroxisome proliferator-activated receptor-γ and cell proliferation

Reproduction

Volumn 138, Issue 3, 2009, Pages 601-608

  Yiallourides, M ^a   Sebert, S P ^a   Wilson, V ^a   Sharkey, D ^a   Rhind, S M ^b   Symonds, M E ^a   Budge, H ^a  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b SCOTTISH CROP RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN C RECEPTOR; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DIET RESTRICTION; FATTY ACID METABOLISM; FEMALE; FETUS GROWTH; GENE EXPRESSION REGULATION; GESTATIONAL AGE; GLUCOSE UTILIZATION; HORMONE ACTION; HORMONE SENSITIVITY; MATERNAL NUTRITION; METABOLIC REGULATION; NONHUMAN; NUTRITIONAL REQUIREMENT; PLACENTA DEVELOPMENT; PLACENTA FUNCTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHEEP; UPREGULATION;

ANIMAL FEED; ANIMALS; CALORIC RESTRICTION; CELL PROLIFERATION; DRUG RESISTANCE; FEMALE; FOOD; GLUCOCORTICOIDS; ION CHANNELS; LIPID METABOLISM; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MITOCHONDRIAL PROTEINS; PLACENTA; PPAR GAMMA; PREGNANCY; PREGNANCY, ANIMAL; SHEEP; TIME FACTORS;

OVIS; OVIS ARIES;

EID: 70449435768     PISSN: 14701626     EISSN: 17417899     Source Type: Journal    
DOI: 10.1530/REP-09-0043     Document Type: Article

References (51)

1. Alaynick WA 2008 Nuclear receptors, mitochondria and lipid metabolism. Mitochondrion 8 329-337.
2. Bauer MK, Breier BH, Harding J, Veldhuis JD & Gluckman PD 1995 The fetal somatotrophic axis during long term maternal undernutrition in sheep; evidence of nutritional regulation in utero. Endocrinology 136 1250-1257.
3. Bispham J, Gopalakrishnan G, Dandrea J, Wilson V, Budge H, Keisler D, Broughton Pipkin F, Stephenson T & Symonds M 2003 Maternal endocrine adaptation throughout pregnancy to nutritional manipulation: consequences for maternal plasma leptin and cortisol and the programming of fetal adipose tissue development. Endocrinology 144 3575-3585. (Pubitemid 36904437)
4. Brameld JM, Mostyn A, Dandrea J, Stephenson TJ, Dawson JM, Buttery PJ & Symonds ME 2000 Maternal nutrition alters the expression of insulin-like growth factors in fetal sheep liver and skeletal muscle. Journal of Endocrinology 167 429-437. (Pubitemid 32047549)
5. Brennan KA, Gopalakrishnan GS, Kurlak L, Rhind SM, Kyle CE, Brooks AN, Rae MT, Olson DM, Stephenson T & Symonds ME 2005 Impact of maternal undernutrition and fetal number on glucocorticoid, growth hormone and insulin-like growth factor receptor mRNA abundance in the ovine fetal kidney. Reproduction 129 151-159. (Pubitemid 40331007)
6. Chandler KD, Leury BJ, Bird AR & Bell AW 1985 Effects of undernutrition and exercise during late pregnancy on uterine, fetal and uteroplacental metabolism in the ewe. British Journal of Nutrition 53 625-635.
7. Clarke L, Heasman L, Juniper D & Symonds M 1998 Maternal nutrition in early-mid gestation and placental size in sheep. British Journal of Nutrition 79 359-364. (Pubitemid 28163898)
8. Correia-da-Silva G, Bell S, Pringle J & Teixeira N 2004 Patterns of uterine cellular proliferation and apoptosis in the implantation site of the rat during pregnancy. Placenta 25 538-547. (Pubitemid 38701897)
9. Dandrea J, Wilson V, Gopalakrishnan G, Heasman L, Budge H, Stephenson T & Symonds ME 2001 Maternal nutritional manipulation of placental growth and glucose transporter-1 abundance in sheep. Reproduction 122 793-800. (Pubitemid 33062034)
10. Echtay KS, Winkler E & Klingenberg M 2000 Coenzyme Q is an obligatory cofactor for uncoupling protein function. Nature 408 609-613.
11. Edwards LJ & McMillen IC 2001 Maternal undernutrition increases arterial blood pressure in the sheep fetus during late gestation. Journal of Physiology 533 561-570.
12. Edwards CR, Benediktsson R, Lindsay RS & Seckl JR 1996 11β-Hydroxysteroid dehydrogenases: key enzymes in determining tissue-specific glucocorticoid effects. Steroids 61 263-269. (Pubitemid 26144433)
13. Ehrhardt RA & Bell AW 1995 Growth and metabolism of the ovine placenta during mid-gestation. Placenta 16 727-741.
14. Fernandes D, Guida E, Koutsoubos V, Harris T, Vadiveloo P, Wilson JW & Stewart AG 1999 Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology 21 77-88. (Pubitemid 129508630)
15. Fowden AL 2003 The insulin-like growth factors and feto-placental growth. Placenta 24 803-812.
16. Fowden AL, Li J & Forhead AJ 1998 Glucocorticoids and the preparation for life after birth: are there long-term consequences of the life insurance? Proceedings of the Nutrition Society 57 113-122.
17. Fowden AL, Ward JW, Wooding FP, Forhead AJ & Constancia M 2006 Programming placental nutrient transport capacity. Journal of Physiology 572 5-15.
18. Fowden AL, Forhead AJ, Coan PM & Burton GJ 2008 The placenta and intrauterine programming. Journal of Neuroendocrinology 20 439-450.
19. Gnanalingham MG, Williams P, Wilson V, Bispham J, Hyatt MA, Pellicano A, Budge H, Stephenson T & Symonds ME 2007 Nutritional manipulation between early to mid-gestation: effects on uncoupling protein-2, glucocorticoid sensitivity, IGF-I receptor and cell proliferation but not apoptosis in the ovine placenta. Reproduction 134 615-623. (Pubitemid 47555055)
20. Hay WW 1995 Current topic: metabolic interrelationships of placenta and fetus. Placenta 16 19-30.
21. Heasman L, Clarke L, Firth K, Stephenson T & Symonds M 1998a Influence of restricted maternal nutrition in early to mid gestation on placental and fetal development at term in sheep. Pediatric Research 44 546-551. (Pubitemid 28447341)
22. Heasman L, Clarke L, Dandrea J, Stephenson T & Symonds ME 1998b Correlation of fetal number with placental mass in sheep. Contemporary Reviews in Obstetrics and Gynaecology 10 275-280. (Pubitemid 29084215)
23. Herrera E 2002 Implications of dietary fatty acids during pregnancy on placental, fetal and postnatal development - a review. Placenta 23 S9-S19. (Pubitemid 40003787)
24. Hull D, Elphick MC & Broughton Pipkin F 1979 The transfer of fatty acids across the sheep placenta. Journal of Developmental Physiology 1 31-45. (Pubitemid 10063611)
25. Jaquiery AL, Oliver MH, Bloomfield FH, Connor KL, Challis JR & Harding JE 2006 Fetal exposure to excess glucocorticoid is unlikely to explain the effects of periconceptional undernutrition in sheep. Journal of Physiology 572 109-118.
26. Jensen EC, Gallaher BW, Breier BH & Harding JE 2002 The effect of a chronic maternal cortisol infusion on the late-gestation fetal sheep. Journal of Endocrinology 174 27-36.
27. Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K & Evans RM 1994 Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. PNAS 91 7355-7359. (Pubitemid 24226862)
28. Livak K & Schmittgen T 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 402-408. (Pubitemid 34164012)
29. McMillen IC & Robinson JS 2005 Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiological Reviews 85 571-633.
30. McMullen S, Osgerby JC, Milne JS, Wallace JM & Wathes DC 2005 The effects of acute nutrient restriction in the mid-gestational ewe on maternal and fetal nutrient status, the expression of placental growth factors and fetal growth. Placenta 26 25-33. (Pubitemid 40123673)
31. Meschia G, Battaglia FC, Hay WW & Sparks JW 1980 Utilization of substrates by the ovine placenta. Federation Proceedings 39 245-249.
32. Miodovnik M, Lavin JP, Harrington DJ, Leung LS, Seeds AE & Clark KE 1982 Effect of maternal ketoacidemia on the pregnant ewe and the fetus. American Journal of Obstetrics and Gynecology 144 585-593.
33. Nunn AV, Bell J & Barter P 2007 The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance. Nuclear Receptor 5 1. (Pubitemid 47029155)
34. Osgerby JC, Wathes DC, Howard D & Gadd TS 2002 The effect of maternal undernutrition on fetal growth. Journal of Endocrinology 173 131-141. (Pubitemid 34428899)
35. Pecqueur C, Bui T, Gelly C, Hauchard J, Barbot C, Bouillaud F, Ricquier D, Miroux B & Thompson CB 2008 Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization. FASEB Journal 22 9-18.
36. Quigley SP, Kleemann DO, Walker SK, Speck PA, Rudiger SR, Nattrass GS, DeBlasio MJ & Owens JA 2008 Effect of variable long-term maternal feed allowance on the development of the ovine placenta and fetus. Placenta 29 539-548.
37. Rae M, Palassio S, Kyle C, Brooks A, Lea R, Miller D & Rhind S 2001 Effect of maternal undernutrition during pregnancy on early ovarian development and subsequent follicular development in sheep fetuses. Reproduction 122 915-922. (Pubitemid 33138572)
38. Robinson JJ, Russel AFF, Treacher TT & Kilkenny JB 1983 In Feeding the Ewe, pp 1-60. Milton Keynes: Meat and Livestock Commission Sheep Improvement Services.
39. Roseboom T, de Rooij S & Painter R 2006 The Dutch famine and its long-term consequences for adult health. Early Human Development 82 485-491. (Pubitemid 44189773)
40. Rumball CW, Harding JE, Oliver MH & Bloomfield FH 2008 Effects of twin pregnancy and periconceptional undernutrition on maternal metabolism, fetal growth and glucose-insulin axis function in ovine pregnancy. Journal of Physiology 586 1399-1411.
41. Russel A 1984 Body condition scoring of sheep. In Practice 6 91-93.
42. Schaiff WT, Barak Y & Sadovsky Y 2006 The pleiotropic function of PPAR gamma in the placenta. Molecular and Cellular Endocrinology 249 10-15.
43. Schneider H 1996 Ontogenic changes in the nutritive function of the placenta. Placenta 17 15-26. (Pubitemid 26108961)
44. Sebert SP, Hyatt MA, Chan LL, Patel N, Bell RC, Keisler D, Stephenson T, Budge H, Symonds ME & Gardner DS 2009 Maternal nutrient restriction between early-to-mid gestation and its impact upon appetite regulation following juvenile obesity. Endocrinology 150 634-641.
45. Sharkey D, Gardner DS, Fainberg HP, Wilson V, Sebert S, Bos P, Bell R, Symonds ME & Budge H 2009 Maternal nutrient restriction during pregnancy differentially alters the unfolded protein response in adipose and renal tissue of obese juvenile offspring. FASEB Journal 23 1314-1324.
46. Sosa C, Abecia JA, Carriquiry M, Forcada F, Martin GB, Palacin I & Meikle A 2009 Early pregnancy alters the metabolic responses to restricted nutrition in sheep. Domestic Animal Endocrinology 36 13-23.
47. Stegmann JHJ 1974 Placental development in sheep. Bijdragen Tot de Dierkunde 44 4-72.
48. Symonds M, Stephenson T, Gardner D & Budge H 2007 Long-term effects of nutritional programming of the embryo and fetus: mechanisms and critical windows. Reproduction Fertility and Development 19 53-63. (Pubitemid 46044731)
49. Thompson MP & Kim D 2004 Links between fatty acids and expression of UCP2 and UCP3 mRNAs. FEBS Letters 568 4-9. (Pubitemid 38757945)
50. Waseem N & Lane D 1990 Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nuclear form. Journal of Cell Science 96 121-129. (Pubitemid 20162680)
51. Whorwood CB, Firth KM, Budge H & Symonds ME 2001 Maternal undernutrition during early- to mid-gestation programmes tissue-specific alterations in the expression of the glucocorticoid receptor, 11β-hydroxysteroid dehydrogenase isoforms and type 1 angiotensin II receptor in neonatal sheep. Endocrinology 142 1778-1785. (Pubitemid 32575520)