Towards improved understanding of protective mechanisms induced by the BCG vaccine

Expert Review of Vaccines

Volumn 8, Issue 11, 2009, Pages 1531-1534

  Villarreal Ramos, Bernardo ^a  

^a VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

BCG; CD8 T cells; TB; Tuberculosis; Vaccination

Indexed keywords

BCG VACCINE; GAMMA INTERFERON; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN SPECIFICITY; BCG VACCINATION; CD8+ T LYMPHOCYTE; CELL POPULATION; DEATH; DEVELOPING COUNTRY; DRUG DOSAGE FORM COMPARISON; HUMAN; IMMUNE RESPONSE; IMMUNITY; INOCULATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; TH1 CELL; TUBERCULOSIS;

EID: 70449427754     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/erv.09.109     Document Type: Review

References (26)

1. Ryan AA, Nambiar JK, Wozniak TM et al. Antigen load governs the differential priming of CD8 T cells in response to the bacille Calmette-Guérin vaccine or Mycobacterium tuberculosis infection. J. Immunol. 182(11), 7172-7177 (2009).
2. WHO. BCG vaccine. WHO Wkly Epidemiol. Rec. 4(79), 27-38 (2004).
3. Calmette A. Preventive vaccination against tuberculosis with BCG. Proc. R. Soc. Med. 24(11), 1481-1490 (1931).
4. Colditz GA, Brewer TF, Berkey CS et al. Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature. JAMA 271(9), 698-702 (1994).
5. Flynn JL, Goldstein MM, Triebold KJ, Koller B, Bloom BR. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl Acad. Sci. USA 89(24), 12013-12017 (1992). (Pubitemid 23004775)
6. + T cells. Infect. Immun. 55(9), 2037-2041 (1987).
7. Orme IM. Aging and immunity to tuberculosis: increased susceptibility of old mice reflects a decreased capacity to generate mediator T lymphocytes. J. Immunol. 138(12), 4414-4418 (1987).
8. Orme IM, Collins FM. Adoptive protection of the Mycobacterium tuberculosis-infected lung. Dissociation between cells that passively transfer protective immunity and those that transfer delayed-type hypersensitivity to tuberculin. Cell. Immunol. 84(1), 113-120 (1984).
9. Sousa AO, Mazzaccaro RJ, Russell RG et al. Relative contributions of distinct MHC class I-dependent cell populations in protection to tuberculosis infection in mice. Proc. Natl Acad. Sci. USA 97(8), 4204-4208 (2000).
10. Turner J, D'Souza CD, Pearl JE et al. CD8- and CD95/95L-dependent mechanisms of resistance in mice with chronic pulmonary tuberculosis. Am. J. Respir. Cell. Mol. Biol. 24(2), 203-209 (2001). (Pubitemid 32152083)
11. van Pinxteren LA, Cassidy JP, Smedegaard BH, Agger EM, Andersen P. Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells. Eur. J. Immunol. 30(12), 3689-3698 (2000). (Pubitemid 32005243)
12. Wang J, Santosuosso M, Ngai P, Zganiacz A, Xing Z. Activation of CD8 T cells by mycobacterial vaccination protects against pulmonary tuberculosis in the absence of CD4 T cells. J. Immunol. 173(7), 4590-4597 (2004). (Pubitemid 39280692)
13. + T cells in bovine tuberculosis in vivo. Infect. Immun. 71(8), 4297-4303 (2003).
14. Chen CY, Huang D, Wang RC et al. A critical role for CD8 T cells in a nonhuman primate model of tuberculosis. PLoS Pathog. 5(4), e1000392 (2009).
15. + T cells requires the production of γ interferon. Infect. Immun. 66(2), 830-834 (1998).
16. Stenger S, Hanson DA, Teitelbaum R et al. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 282(5386), 121-125 (1998). (Pubitemid 28471143)
17. Endsley JJ, Furrer JL, Endsley MA et al. Characterization of bovine homologues of granulysin and NK-lysin. J. Immunol. 173(4), 2607-2614 (2004).
18. van der Wel N, Hava D, Houben D et al. M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell 129(7), 1287-1298 (2007). (Pubitemid 46962098)
19. Russell MS, Iskandar M, Mykytczuk OL, Nash JH, Krishnan L, Sad S. A reduced antigen load in vivo, rather than weak inflammation, causes a substantial delay in CD8+ T cell priming against Mycobacterium bovis (bacillus Calmette-Guérin). J. Immunol. 179(1), 211-220 (2007). (Pubitemid 46986536)
20. Mahairas GG, Sabo PJ, Hickey MJ, Singh DC, Stover CK. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J. Bacteriol. 178(5), 1274-1282 (1996).
21. Berthet F-X, Rasmussen PB, Rosenkrands I, Andersen P, Gicquel B. A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular- mass culture filtrate protein (CFP-10). Microbiology 144(11), 3195-3203 (1998). (Pubitemid 28515598)
22. + T-cell population. Vaccine 27(2), 270-279 (2009).
23. Wang J, Thorson L, Stokes RW et al. Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis. J. Immunol. 173(10), 6357-6365 (2004). (Pubitemid 39487795)
24. Forbes EK, Sander C, Ronan EO et al. Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice. J. Immunol. 181(7), 4955-4964 (2008).
25. Santosuosso M, Zhang X, McCormick S, Wang J, Hitt M, Xing Z. Mechanisms of mucosal and parenteral tuberculosis vaccinations: adenoviral-based mucosal immunization preferentially elicits sustained accumulation of immune protective CD4 and CD8 T cells within the airway lumen. J. Immunol. 174(12), 7986-7994 (2005). (Pubitemid 40806309)
26. Huang LP, Lyu S-C, Clayberger C, Krensky AM. Granulysin-mediated tumor rejection in transgenic mice. J. Immunol. 178(1), 77-84 (2007). (Pubitemid 46033589)