Retinal vascular fractal dimension and risk of early diabetic retinopathy: A prospective study of children and adolescents with type 1 diabetes

Diabetes Care

Volumn 32, Issue 11, 2009, Pages 2081-2083

  Shueh, Wen Lim ^a   Cheung, Ning ^a   Wang, Jie J ^a,b   Donaghue, Kim C ^b   Liew, Gerald ^b   Islam, F M Amirul ^a   Jenkins, Alicia J ^a   Wong, Tien Y ^a,c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C;

ADOLESCENT; ADULT; ARTICLE; BLOOD VESSEL DIAMETER; CHILD; COMPUTER PROGRAM; DIABETIC RETINOPATHY; DISEASE COURSE; DISEASE DURATION; EYE PHOTOGRAPHY; FOLLOW UP; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; RETINA BLOOD VESSEL; RISK ASSESSMENT; RISK FACTOR; SCHOOL CHILD;

ADOLESCENT; CHILD; DIABETES MELLITUS, TYPE 1; DIABETIC RETINOPATHY; FOLLOW-UP STUDIES; FRACTALS; FUNCTIONAL LATERALITY; HUMANS; INCIDENCE; PATIENT SELECTION; PHOTOGRAPHY; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; RETINAL VESSELS; RISK FACTORS; YOUNG ADULT;

EID: 70449426833     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc09-0719     Document Type: Article

References (15)

1. Macgillivray TJ, Patton N, Doubal FN, Graham C, Wardlaw JM. Fractal analysis of the retinal vascular network in fundus images. Conf Proc IEEE Eng Med Biol Soc 2007;2007:6456-6459
2. Mainster MA. The fractal properties of retinal vessels: embryological and clinical implications. Eye 1990;4:235-241
3. Masters BR. Fractal analysis of the vascular tree in the human retina. Annu Rev Biomed Eng 2004;6:427-452 (Pubitemid 39213987)
4. Avakian A, Kalina RE, Sage EH, Rambhia AH, Elliott KE, Chuang EL, Clark JI, Hwang JN, Parsons-Wingerter P. Fractal analysis of region-based vascular change in the normal and non-proliferative diabetic retina. Curr Eye Res 2002;24:274-280 (Pubitemid 35155743)
5. Daxer A. Characterisation of the neovascularisation process in diabetic retinopathy by means of fractal geometry: diagnostic implications. Graefes Arch Clin Exp Ophthalmol 1993;231:681-686 (Pubitemid 24026551)
6. Daxer A. The fractal geometry of proliferative diabetic retinopathy: implications for the diagnosis and the process of retinal vasculogenesis. Curr Eye Res 1993;12:1103-1109 (Pubitemid 24033646)
7. Daxer A. Mechanisms in retinal vasculogenesis: an analysis of the spatial branching site correlation. Curr Eye Res 1995;14:251-254
8. Liew G, Wang JJ, Cheung N, Zhang YP, Hsu W, Lee ML, Mitchell P, Tikellis G, Taylor B, Wong TY. The retinal vasculature as a fractal: methodology, reliability, and relationship to blood pressure. Ophthalmology 2008;115:1951-1956
9. Cheung N, Donaghue KC, Liew G, Rogers SL, Wang JJ, Lim SW, Jenkins AJ, Hsu W, Li Lee M, Wong TY. Quantitative assessment of early diabetic retinopathy using fractal analysis. Diabetes Care 2009;32:106-110
10. Donaghue KC, Fung AT, Hing S, Fairchild J, King J, Chan A, Howard NJ, Silink M. The effect of prepubertal diabetes duration on diabetes. Microvascular complications in early and late adolescence. Diabetes Care 1997;20:77-80
11. Maguire A, Chan A, Cusumano J, Hing S, Craig M, Silink M, Howard N, Donaghue K. The case for biennial retinopathy screening in children and adolescents. Diabetes Care 2005;28:509-513 (Pubitemid 40315305)
12. Mohsin F, Craig ME, Cusumano J, Chan AK, Hing S, Lee JW, Silink M, Howard NJ, Donaghue KC. Discordant trends in microvascular complications in adolescents with type 1 diabetes from 1990 to 2002. Diabetes Care 2005;28:1974-1980
13. Cheung N, Rogers SL, Donaghue KC, Jenkins AJ, Tikellis G, Wong TY. Retinal arteriolar dilation predicts retinopathy in adolescents with type 1 diabetes. Diabetes Care 2008;31:1842-1846
14. Rogers SL, Tikellis G, Cheung N, Tapp R, Shaw J, Zimmet PZ, Mitchell P, Wang JJ, Wong TY. Retinal arteriolar caliber predicts incident retinopathy: the Australian Diabetes, Obesity and Lifestyle (AusDiab) study. Diabetes Care 2008;31:761-763
15. Nguyen TT, Wang JJ, Sharrett AR, Islam FM, Klein R, Klein BE, Cotch MF, Wong TY. Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care 2008;31:544-549