-
1
-
-
0013426707
-
Procedure and apparatus for preservation in the lyophile form of serum and other biological substances
-
Flosdorf EW, Mudd S. Procedure and apparatus for preservation in the lyophile form of serum and other biological substances. J. Immunol. 29, 389-425 (1935).
-
(1935)
J. Immunol.
, vol.29
, pp. 389-425
-
-
Flosdorf, E.W.1
Mudd, S.2
-
2
-
-
0025265488
-
Comparision of the effect of various chemical stabilisers and lyophilization cycles on the thermostability of a Vero cell adapted rinderpest vaccine
-
Landmark paper describing the comparision of three stabilizers, three lyophilization schedules and three diluents at 37°C and three higher temperature ranges: 42, 45 and 56°C. The live-attenuated rinderpest vaccine was used. This is one of the earliest systematically planned studies on the thermostability of a veterinary vaccine
-
Mariner JC, House JA, Sollod AE et al. Comparision of the effect of various chemical stabilisers and lyophilization cycles on the thermostability of a Vero cell adapted rinderpest vaccine. Vet. Microbiol. 21, 195-209 (1990). •• Landmark paper describing the comparision of three stabilizers, three lyophilization schedules and three diluents at 37°C and three higher temperature ranges: 42, 45 and 56°C. The live-attenuated rinderpest vaccine was used. This is one of the earliest systematically planned studies on the thermostability of a veterinary vaccine.
-
(1990)
Vet. Microbiol.
, vol.21
, pp. 195-209
-
-
Mariner, J.C.1
House, J.A.2
Sollod, A.E.3
-
3
-
-
2342571556
-
Modelling effect of physical and chemical parameters on heat inactivation kinetics of hepatitis A virus in a fruit model system
-
Deboosere'N O, Legeay Y, Caudrelier M et al. Modelling effect of physical and chemical parameters on heat inactivation kinetics of hepatitis A virus in a fruit model system. Intl. J. Food Microbiol. 93(1), 73-85 (2004).
-
(2004)
Intl. J. Food Microbiol.
, vol.93
, Issue.1
, pp. 73-85
-
-
Deboosere'N, O.1
Legeay, Y.2
Caudrelier, M.3
-
4
-
-
70449432118
-
Lyophilization of vaccines from methods in molecular medicine
-
(2nd Edition). Robinson A, Hudson MJ, Cranage MP (Eds). Humana Press, NJ, USA An excellent compilation of all relevant topics in the field of vaccinology. The chapter on lyophilization of vaccines is of special interest. The review on temperature-sensitive mutants is also noteworthy
-
Adams GDJ. Lyophilization of vaccines from methods in molecular medicine. In: Vaccine Protocols (2nd Edition). Robinson A, Hudson MJ, Cranage MP (Eds). Humana Press, NJ, USA (2003). •• An excellent compilation of all relevant topics in the field of vaccinology. The chapter on lyophilization of vaccines is of special interest. The review on temperature-sensitive mutants is also noteworthy.
-
(2003)
Vaccine Protocols
-
-
Adams, G.D.J.1
-
5
-
-
0030339883
-
Stability of yellow fever vaccine
-
Monath TP. Stability of yellow fever vaccine. Dev. Biol. Stand. 87, 219-225 (1996).
-
(1996)
Dev. Biol. Stand.
, vol.87
, pp. 219-225
-
-
Monath, T.P.1
-
6
-
-
0021591748
-
17D lyophilize. I. Essai de substances protectrices
-
17D lyophilize. I. Essai de substances protectrices. J. Biol. Stand. 12, 435-442 (1984).
-
(1984)
J. Biol. Stand.
, vol.12
, pp. 435-442
-
-
Barme, M.1
Bronnert, C.2
-
8
-
-
85025396219
-
The use of yellow fever modified by in vitro cultivation for human immunization
-
Theiler M, Smith HH. The use of yellow fever modified by in vitro cultivation for human immunization. J. Exp. Med. 65, 787-800 (1937).
-
(1937)
J. Exp. Med.
, vol.65
, pp. 787-800
-
-
Theiler, M.1
Smith, H.H.2
-
9
-
-
0029115185
-
Thermostabilisation of live virus vaccines by heavy water
-
10 potency loss after 3 days of storing the Sabin 3 strain of poliovirus at 45°C. This paper unequivocally describes the importance of heavy water as a candidate for stabilization of live virus vaccine thermostability
-
10 potency loss after 3 days of storing the Sabin 3 strain of poliovirus at 45°C. This paper unequivocally describes the importance of heavy water as a candidate for stabilization of live virus vaccine thermostability.
-
(1995)
Vaccine
, vol.13
, pp. 1058-1063
-
-
Wu, R.1
Georgescu, M.2
Delpeyroux, F.3
-
10
-
-
0030330565
-
The replacement of water with deuterium oxide significantly improves the thermal stability of the oral poliovirus vaccine
-
Crainic R, Wu R, Otelea D et al. The replacement of water with deuterium oxide significantly improves the thermal stability of the oral poliovirus vaccine. Dev. Biol. Stand. 87, 161-166 (1996).
-
(1996)
Dev. Biol. Stand.
, vol.87
, pp. 161-166
-
-
Crainic, R.1
Wu, R.2
Otelea, D.3
-
11
-
-
0032452483
-
17D yellow fever virus vaccine using different stabilizers
-
2O shows the best stabilizing effect under thermal treatment at 37°C for 24 h
-
2O shows the best stabilizing effect under thermal treatment at 37°C for 24 h.
-
(1998)
Biologicals
, vol.26
, pp. 309-316
-
-
Adebayo, A.A.1
Sim-Brandenburg, J.W.2
Emmel, H.3
-
12
-
-
0008863560
-
Some factors in the interpretation of protein denaturation
-
Kauzmann W. Some factors in the interpretation of protein denaturation. Adv. Prot. Chem. 14, 1-63 (1959).
-
(1959)
Adv. Prot. Chem.
, vol.14
, pp. 1-63
-
-
Kauzmann, W.1
-
13
-
-
0025370815
-
Dominant forces in protein folding
-
Dill KA. Dominant forces in protein folding. Biochem. 29, 7133-7155 (1990).
-
(1990)
Biochem.
, vol.29
, pp. 7133-7155
-
-
Dill, K.A.1
-
14
-
-
0028921999
-
Demonstration of positionally disordered water within a protein hydrophobic cavity by NMR
-
Ernst JA, Clubb RT, Zhou H et al. Demonstration of positionally disordered water within a protein hydrophobic cavity by NMR. Science 267, 1813-1817 (1995).
-
(1995)
Science
, vol.267
, pp. 1813-1817
-
-
Ernst, J.A.1
Clubb, R.T.2
Zhou, H.3
-
15
-
-
0026326956
-
Protein hydration in aqueous solution
-
Otting G, Liepinsh E, Wuthrich K. Protein hydration in aqueous solution. Science 254, 974-980 (1991).
-
(1991)
Science
, vol.254
, pp. 974-980
-
-
Otting, G.1
Liepinsh, E.2
Wuthrich, K.3
-
16
-
-
0028937274
-
Protein hydration dynamics in aqueous solution
-
Denisov VP, Halle B. Protein hydration dynamics in aqueous solution. J. Mol. Biol. 245, 698-709 (1995).
-
(1995)
J. Mol. Biol.
, vol.245
, pp. 698-709
-
-
Denisov, V.P.1
Halle, B.2
-
18
-
-
0035937261
-
Core and surface mutations affect folding kinetics, stability, and cooperativity I IL-1β: Does alteration in buried water play a role?
-
Covalt JC, Roy M, Jennings PA. Core and surface mutations affect folding kinetics, stability, and cooperativity I IL-1β: does alteration in buried water play a role? J. Mol. Biol. 307, 657-669 (2001).
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 657-669
-
-
Covalt, J.C.1
Roy, M.2
Jennings, P.A.3
-
20
-
-
1542618416
-
Water and proteins: A love-hate relationship
-
Levy Y, Onuchic JN. Water and proteins: a love-hate relationship. Proc. Natl Acad. Sci. USA 101(10), 3325-3326 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.10
, pp. 3325-3326
-
-
Levy, Y.1
Onuchic, J.N.2
-
21
-
-
70449437380
-
Thermodynamic and dynamic properties of water
-
Neidle S, Fuller W (Eds). Macmillan Press, London, UK
-
Ludemann HD. Thermodynamic and dynamic properties of water. In: Topics in Molecular and Structural Biology. Neidle S, Fuller W (Eds). Macmillan Press, London, UK, 45-59 (1993).
-
(1993)
Topics in Molecular and Structural Biology
, pp. 45-59
-
-
Ludemann, H.D.1
-
22
-
-
0004084360
-
Water structure
-
Neidle S, Fuller W (Eds). Macmillan Press, London, UK
-
Savage HFJ. Water structure. In: Topics in Molecular and Structural Biology. Neidle S, Fuller W (Eds). Macmillan Press, London, UK, 3-44 (1993).
-
(1993)
Topics in Molecular and Structural Biology
, pp. 3-44
-
-
Savage, H.F.J.1
-
24
-
-
0005992442
-
Effects de l'eau sur le development du poliovirus en function de la temperature
-
Lwoff A, Lwoff M. Effects de l'eau sur le development du poliovirus en function de la temperature. CR Acad. Sci. 251, 3131-3132 (1960).
-
(1960)
CR Acad. Sci.
, vol.251
, pp. 3131-3132
-
-
Lwoff, A.1
Lwoff, M.2
-
26
-
-
0032772532
-
Pharmacological uses and perspectives of heavy water and deuterated compounds
-
Kushner DJ, Baker A, Dunstall TG. Pharmacological uses and perspectives of heavy water and deuterated compounds. Canadian J. Physiol. Pharmacol. 77(2), 79-88 (1999).
-
(1999)
Canadian J. Physiol. Pharmacol.
, vol.77
, Issue.2
, pp. 79-88
-
-
Kushner, D.J.1
Baker, A.2
Dunstall, T.G.3
-
28
-
-
0009638759
-
Canada's heavy water story
-
Shemilt LW (Ed.). Canadian Society of Chemical Engineering, ON, Canada
-
Rae HK. Canada's heavy water story. In: Chemical Engineering in Canada: A Historical Perspective. Shemilt LW (Ed.). Canadian Society of Chemical Engineering, ON, Canada, 334-361 (1991).
-
(1991)
Chemical Engineering in Canada: A Historical Perspective
, pp. 334-361
-
-
Rae, H.K.1
-
32
-
-
0345055564
-
Primordial deuterium and the big bang
-
Hogan CJ. Primordial deuterium and the big bang. Sci. Am. 6, 68-73 (1996).
-
(1996)
Sci. Am.
, vol.6
, pp. 68-73
-
-
Hogan, C.J.1
-
33
-
-
0026653655
-
Protein folding studied using hydrogen-exchange labeling and two-dimensional NMR
-
Englander SW, Mayne L. Protein folding studied using hydrogen-exchange labeling and two-dimensional NMR. Annu. Rev. Biophys. Biomol. Struct. 21, 243-265 (1992).
-
(1992)
Annu. Rev. Biophys. Biomol. Struct.
, vol.21
, pp. 243-265
-
-
Englander, S.W.1
Mayne, L.2
-
34
-
-
0025142485
-
An antibody binding site on cytochrome C defined by hydrogen exchange and two dimensional NMR
-
Paterson Y, Englander SW, Roder H. An antibody binding site on cytochrome C defined by hydrogen exchange and two dimensional NMR. Science 249, 755-759 (1990).
-
(1990)
Science
, vol.249
, pp. 755-759
-
-
Paterson, Y.1
Englander, S.W.2
Roder, H.3
-
35
-
-
0009942589
-
-
University Park Press, MD, USA
-
Cleland WN, O'Leary MH, Northrop DD. Isotope effects on enzyme-catalyzed reactions. University Park Press, MD, USA, 1-303 (1976).
-
(1976)
Isotope Effects on Enzyme-catalyzed Reactions
, pp. 1-303
-
-
Cleland, W.N.1
O'Leary, M.H.2
Northrop, D.D.3
-
36
-
-
0028326438
-
Theory for the observed isotope effects on the formation of multiple products by different kinetic mechanisms of cytochrome P450 enzymes
-
Gillette JR, Darbyshire JF, Sugiyama Y. Theory for the observed isotope effects on the formation of multiple products by different kinetic mechanisms of cytochrome P450 enzymes. Biochem. 33, 2927-2937 (1994).
-
(1994)
Biochem.
, vol.33
, pp. 2927-2937
-
-
Gillette, J.R.1
Darbyshire, J.F.2
Sugiyama, Y.3
-
37
-
-
0028981698
-
H2-forming N5, N10- Methylenetetrahydromethanopterin dehydrogenase: Mechanism of H2 formation analyzed using hydrogen isotopes
-
Klein AR, Fernandez VM, Thauer RK. H2-forming N5, N10- methylenetetrahydromethanopterin dehydrogenase: mechanism of H2 formation analyzed using hydrogen isotopes. FEBS Lett. 368, 203-206 (1995).
-
(1995)
FEBS Lett.
, vol.368
, pp. 203-206
-
-
Klein, A.R.1
Fernandez, V.M.2
Thauer, R.K.3
-
38
-
-
0025329396
-
Glutathione reductase: Comparison of steady-state and rapid reaction primary kinetic isotope effects exhibited by the yeast, spinach and Escherichia coli enzymes
-
Vanoni MA, Wong KK, Ballou DP et al. Glutathione reductase: comparison of steady-state and rapid reaction primary kinetic isotope effects exhibited by the yeast, spinach and Escherichia coli enzymes. Biochem. 29, 5790-5796 (1990).
-
(1990)
Biochem.
, vol.29
, pp. 5790-5796
-
-
Vanoni, M.A.1
Wong, K.K.2
Ballou, D.P.3
-
39
-
-
0024376998
-
Solvent suppression
-
Hore PJ. Solvent suppression. Methods Enzymol. 176, 64-77 (1989).
-
(1989)
Methods Enzymol.
, vol.176
, pp. 64-77
-
-
Hore, P.J.1
-
40
-
-
0024329563
-
Two-dimensional nuclear magnetic resonance spectroscopy of proteins: An overview
-
Markley JL. Two-dimensional nuclear magnetic resonance spectroscopy of proteins: an overview. Methods Enzymol. 176, 12-64 (1989).
-
(1989)
Methods Enzymol.
, vol.176
, pp. 12-64
-
-
Markley, J.L.1
-
41
-
-
0025347732
-
Uniform and selective deuteration in two-dimensional NMR of proteins
-
LeMaster DM. Uniform and selective deuteration in two-dimensional NMR of proteins. Annu. Rev. Biophys. Biophys. Chem. 19, 243-266 (1990).
-
(1990)
Annu. Rev. Biophys. Biophys. Chem.
, vol.19
, pp. 243-266
-
-
LeMaster, D.M.1
-
42
-
-
0022994017
-
Use of deuterated proteins in nuclear magnetic resonance
-
Rösch P. Use of deuterated proteins in nuclear magnetic resonance. Nature 323, 670 (1986).
-
(1986)
Nature
, vol.323
, pp. 670
-
-
Rösch, P.1
-
43
-
-
0027177825
-
Large-scale preparation of fully deuterated cell components: Ribosomes from Escherichia coli with high biological activity
-
Vanatulu K, Paalme T, Vilu R et al. Large-scale preparation of fully deuterated cell components: ribosomes from Escherichia coli with high biological activity. Eur. J. Biochem. 216, 315-321 (1993).
-
(1993)
Eur. J. Biochem.
, vol.216
, pp. 315-321
-
-
Vanatulu, K.1
Paalme, T.2
Vilu, R.3
-
47
-
-
0020345922
-
Deuterium and tritium kinetic isotope effects on initial rates
-
Northrop DB. Deuterium and tritium kinetic isotope effects on initial rates. Methods Enzymol. 87, 607-625 (1982).
-
(1982)
Methods Enzymol.
, vol.87
, pp. 607-625
-
-
Northrop, D.B.1
-
48
-
-
0001894312
-
Deuterium isotope effects in the metabolism of drugs and xenobiotics: Implications for drug design
-
Foster AB. Deuterium isotope effects in the metabolism of drugs and xenobiotics: implications for drug design. Adv. Drug Res. 14, 1-40 (1985).
-
(1985)
Adv. Drug Res.
, vol.14
, pp. 1-40
-
-
Foster, A.B.1
-
49
-
-
0028210147
-
Deuterium isotope effects on A-ring and D-ring metabolism of testosterone by CYP2C11: Evidence for dissociation of activated enzyme substrate complexes
-
Darbyshire JF, Gillette JR, Nagata K et al. Deuterium isotope effects on A-ring and D-ring metabolism of testosterone by CYP2C11: evidence for dissociation of activated enzyme substrate complexes. Biochem. 33, 2938-2944 (1994).
-
(1994)
Biochem.
, vol.33
, pp. 2938-2944
-
-
Darbyshire, J.F.1
Gillette, J.R.2
Nagata, K.3
-
50
-
-
0028903042
-
β-secondary and solvent deuterium kinetic isotope effects and the mechanisms of base and acid-catalyzed hydrolysis of penicillanic acid
-
Deraniyagala SA, Adediran SA, Pratt RF. β-secondary and solvent deuterium kinetic isotope effects and the mechanisms of base and acid-catalyzed hydrolysis of penicillanic acid. J. Org. Chem. 60, 1619-1625 (1995).
-
(1995)
J. Org. Chem.
, vol.60
, pp. 1619-1625
-
-
Deraniyagala, S.A.1
Adediran, S.A.2
Pratt, R.F.3
-
51
-
-
0009574738
-
Biotechnological potential of heavy water and deuterated compounds
-
Levin M, Grim C, Angle JA (Eds). University of Maryland Biotechnology Institute Publication 1003, MD, USA, Excellent review of the scope and diversity of the application of deuterium in biological sciences. In addition, the production of deuterated glycerol by Dunaleilla spp., a salt-tolerant algae, has been discussed in detail
-
Kushner DJ, Baker A, Dunstall TG. Biotechnological potential of heavy water and deuterated compounds. Proceedings of Biotechnology Risk Assessment Symposium. Ottawa, Canada, 23-25 June 1996. Levin M, Grim C, Angle JA (Eds). University of Maryland Biotechnology Institute Publication 1003, MD, USA, 75-89 (1997). •• Excellent review of the scope and diversity of the application of deuterium in biological sciences. In addition, the production of deuterated glycerol by Dunaleilla spp., a salt-tolerant algae, has been discussed in detail.
-
(1997)
Proceedings of Biotechnology Risk Assessment Symposium. Ottawa, Canada, 23-25 June 1996
, pp. 75-89
-
-
Kushner, D.J.1
Baker, A.2
Dunstall, T.G.3
-
52
-
-
70449446257
-
Structural and ultrastructural changes in fish spleen induced by heavy water
-
Buzgariu W, Caloianu M, Lazar S. Structural and ultrastructural changes in fish spleen induced by heavy water. Romanian J. Biol. Sci. 1(IX), 5-6 (1997).
-
(1997)
Romanian J. Biol. Sci.
, vol.1
, Issue.9
, pp. 5-6
-
-
Buzgariu, W.1
Caloianu, M.2
Lazar, S.3
-
53
-
-
0031597951
-
Effects of heavy and deuterium-depleted water on vascular reactivity
-
Haulica I, Peculea M, Stefanescu I, Titescu GH, Todiras M, Bild W. Effects of heavy and deuterium-depleted water on vascular reactivity. Roman. J. Physiol. 35(1-2), 25-32 (1998).
-
(1998)
Roman. J. Physiol.
, vol.35
, Issue.1-2
, pp. 25-32
-
-
Haulica, I.1
Peculea, M.2
Stefanescu, I.3
Titescu, G.H.4
Todiras, M.5
Bild, W.6
-
54
-
-
18444370068
-
Deuterium in biology
-
Kritchevsky D. Deuterium in biology. Ann. NY Acad. Sci. 84(16), 575 (1960).
-
(1960)
Ann. NY Acad. Sci.
, vol.84
, Issue.16
, pp. 575
-
-
Kritchevsky, D.1
-
55
-
-
0025695776
-
Radioactivity in deuterated compounds
-
Homma Y, Murase Y. Radioactivity in deuterated compounds. J. Radioanal. Nucl. Chem. 146, 205-210 (1990).
-
(1990)
J. Radioanal. Nucl. Chem.
, vol.146
, pp. 205-210
-
-
Homma, Y.1
Murase, Y.2
-
57
-
-
0018788147
-
Deuterium method for measuring milk intake in babies
-
Coward WA. Deuterium method for measuring milk intake in babies. Lancet 11, 309 (1979).
-
(1979)
Lancet
, vol.11
, pp. 309
-
-
Coward, W.A.1
-
58
-
-
18744415724
-
Comparative measurements of total body water in healthy volunteers by online breath deuterium measurement and other near-subject methods
-
David S, Engel B, Diskin AM, Spanel P, Davies SJ. Comparative measurements of total body water in healthy volunteers by online breath deuterium measurement and other near-subject methods. Am. J. Clin. Nutr. 76, 1295-1301 (2002).
-
(2002)
Am. J. Clin. Nutr.
, vol.76
, pp. 1295-1301
-
-
David, S.1
Engel, B.2
Diskin, A.M.3
Spanel, P.4
Davies, S.J.5
-
59
-
-
0032189484
-
Energy metabolism in infants and children
-
Wells JCK. Energy metabolism in infants and children. Nutrition 14(10), 817-820 (1998).
-
(1998)
Nutrition
, vol.14
, Issue.10
, pp. 817-820
-
-
Wells, J.C.K.1
-
61
-
-
0029843763
-
Energy metabolism: Overview of recent methods used in human studies
-
Schutz Y, Deurenberg P. Energy metabolism: overview of recent methods used in human studies. Ann. Nutr. Metab. 40, 183-193 (1996).
-
(1996)
Ann. Nutr. Metab.
, vol.40
, pp. 183-193
-
-
Schutz, Y.1
Deurenberg, P.2
-
62
-
-
70449410280
-
Stable isotope usage in developing countries: Safe tracer tools to measure human nutritional status 'silent tracers' can help health professionals answer some important questions
-
4
-
Klein PD, Klein ER. Stable isotope usage in developing countries: safe tracer tools to measure human nutritional status 'silent tracers' can help health professionals answer some important questions. IAEA Bulletin (4/1987).
-
(1987)
IAEA Bulletin
-
-
Klein, P.D.1
Klein, E.R.2
-
63
-
-
0009648462
-
The biology of heavy water
-
Katz JJ. The biology of heavy water. Sci. Am. 203, 106-115 (1960).
-
(1960)
Sci. Am.
, vol.203
, pp. 106-115
-
-
Katz, J.J.1
-
65
-
-
0035671904
-
Technologies to improve immunization safety
-
Clements CJ, Aguado MT, Jódar L. Technologies to improve immunization safety. Drug Saf. 24(14), 1019-1026 (2001).
-
(2001)
Drug Saf.
, vol.24
, Issue.14
, pp. 1019-1026
-
-
Clements, C.J.1
Aguado, M.T.2
Jódar, L.3
-
66
-
-
0028034935
-
Human immunization in developing countries - Practical and theoretical problems and prospects
-
Arya SC. Human immunization in developing countries - practical and theoretical problems and prospects. Vaccine 12, 1423-1435 (1994).
-
(1994)
Vaccine
, vol.12
, pp. 1423-1435
-
-
Arya, S.C.1
-
67
-
-
3042692494
-
Influenza vaccine powder formulation development: Spray- Freezedrying and stability evaluation
-
Maa YF, Ameri M, Shu C, Payne LG, Chen DX. Influenza vaccine powder formulation development: spray- freezedrying and stability evaluation. J. Pharm. Sci. 93, 1912-1923 (2004).
-
(2004)
J. Pharm. Sci.
, vol.93
, pp. 1912-1923
-
-
Maa, Y.F.1
Ameri, M.2
Shu, C.3
Payne, L.G.4
Chen, D.X.5
-
68
-
-
0034703815
-
Xerovac: An ultra rapid method for the dehydaration and preservation of live attenuated rinderpest and peste des petits ruminants vaccines
-
Worrall EE, Litamoi JK, Seck BM, Ayelet G. Xerovac: an ultra rapid method for the dehydaration and preservation of live attenuated rinderpest and peste des petits ruminants vaccines. Vaccine 19, 834-839 (2000).
-
(2000)
Vaccine
, vol.19
, pp. 834-839
-
-
Worrall, E.E.1
Litamoi, J.K.2
Seck, B.M.3
Ayelet, G.4
-
69
-
-
0021954618
-
Thermal-pH inactivation of herpes simplex virus: Interdependence of the medium composition and the pH on the rate of inactivation
-
Lancz G, Sample J. Thermal-pH inactivation of herpes simplex virus: interdependence of the medium composition and the pH on the rate of inactivation. Arch. Virol. 84, 141-146 (1985).
-
(1985)
Arch. Virol.
, vol.84
, pp. 141-146
-
-
Lancz, G.1
Sample, J.2
-
70
-
-
0017058647
-
Effect of pH, salts and temperature on the infectivity and physical integrity of enteroviruses
-
Salo RJ, Cliver DO. Effect of pH, salts and temperature on the infectivity and physical integrity of enteroviruses. Arch. Virol. 52, 269-282 (1976).
-
(1976)
Arch. Virol.
, vol.52
, pp. 269-282
-
-
Salo, R.J.1
Cliver, D.O.2
-
72
-
-
0024452997
-
Erhöhte gehirn-affinitiit vonJ-markierten N-(alkyl)-amphetaminen nach deuterierung
-
Wenzel M. Erhöhte gehirn-affinitiit vonJ-markierten N-(alkyl)-amphetaminen nach deuterierung. J. Labelled Comp. Radiopharm. 27, 1143-1155 (1989).
-
(1989)
J. Labelled Comp. Radiopharm.
, vol.27
, pp. 1143-1155
-
-
Wenzel, M.1
-
73
-
-
0024826059
-
Modification thermal response of chlorella ellipsoidea by deuteration
-
Unno K, Shimba S, Okada S. Modification of thermal response of Chlorella ellipoidea by deuteration. Chem. Pharm. Bull. 37, 3047-3049 (1989). (Pubitemid 20056087)
-
(1989)
Chemical and Pharmaceutical Bulletin
, vol.37
, Issue.11
, pp. 3047-3049
-
-
Unno, K.1
Shimba, S.2
Okada, S.3
-
74
-
-
70449443058
-
Alterations in the heat response of Chlorella ellipsoidea by deuteration
-
Unno K, Okada S. Alterations in the heat response of Chlorella ellipsoidea by deuteration. Plant Cell Physiol. 32, 113-120 (1991).
-
(1991)
Plant Cell Physiol.
, vol.32
, pp. 113-120
-
-
Unno, K.1
Okada, S.2
-
75
-
-
0027954085
-
Deuteration causes the decreased induction of heat-shock proteins and increased sensitivity to heat denaturation of proteins in
-
Unno K, Okada S. Deuteration causes the decreased induction of heat-shock proteins and increased sensitivity to heat denaturation of proteins in Chlorella. Plant Cell Physiol. 35, 197-202 (1994).
-
(1994)
Chlorella. Plant Cell Physiol.
, vol.35
, pp. 197-202
-
-
Unno, K.1
Okada, S.2
-
76
-
-
0028873785
-
Chaperonin-repairable subtle incompleteness of protein assembly induced by a substitution of hydrogen with deuterium: Effect of GroE on deuterated ribulose 1,5-bisphosphate carboxylase
-
Yokogaki S, Unno K, Oku N et al. Chaperonin-repairable subtle incompleteness of protein assembly induced by a substitution of hydrogen with deuterium: effect of GroE on deuterated ribulose 1,5-bisphosphate carboxylase. Plant Cell Physiol. 36, 419-423 (1995).
-
(1995)
Plant Cell Physiol.
, vol.36
, pp. 419-423
-
-
Yokogaki, S.1
Unno, K.2
Oku, N.3
-
77
-
-
0027744439
-
Deuterium oxide normalizes blood pressure and elevated cytosolic calcium in rats with ethanol-induced hypertension
-
Vasdev S, Gupta IP, Sampson CA et al. Deuterium oxide normalizes blood pressure and elevated cytosolic calcium in rats with ethanol-induced hypertension. Canadian J. Cardiol. 9, 802-808 (1993). (Pubitemid 24006122)
-
(1993)
Canadian Journal of Cardiology
, vol.9
, Issue.9
, pp. 802-808
-
-
Vasdev, S.1
Gupta, I.P.2
Sampson, C.A.3
Longerich, L.4
Parai, S.5
-
78
-
-
0028630657
-
Fructose-induced hypertension, hyperglyceridemia and elevated cytosolic calcium in rats: Prevention by deuterium oxide
-
Vasdev S, Prabhakaran VM, Whelan M, Ford CA, Longerich L, Parai S. Fructose-induced hypertension, hyperglyceridemia and elevated cytosolic calcium in rats: prevention by deuterium oxide. Artery 21, 124-127 (1994).
-
(1994)
Artery
, vol.21
, pp. 124-127
-
-
Vasdev, S.1
Prabhakaran, V.M.2
Whelan, M.3
Ford, C.A.4
Longerich, L.5
Parai, S.6
-
79
-
-
0021680715
-
2O
-
Lin PS, Hefter K, Ho KC. Modification of membrane function, protein synthesis and heat killing effect in cultured Chinese hamster cells by glycerol and D2O. Cancer Res. 44, 5776-5784 (1984). (Pubitemid 15183593)
-
(1984)
Cancer Research
, vol.44
, Issue.12 I
, pp. 5776-5784
-
-
Lin, P.-S.1
Hefter, K.2
Ho, K.-C.3
-
81
-
-
0019248704
-
Deuterium oxide protects against hyperthermic cell death: Evidence for role of interfacial water
-
McIver DJL, Schurch S, Sridhar R. Deuterium oxide protects against hyperthermic cell death: evidence for role of interfacial water. Physiol. Chem. Phys. 12, 369-372 (1980).
-
(1980)
Physiol. Chem. Phys.
, vol.12
, pp. 369-372
-
-
McIver, D.J.L.1
Schurch, S.2
Sridhar, R.3
-
83
-
-
0023198719
-
Myristylation of picornavirus capsid protein VP4 and its structural significance
-
DOI 10.1038/327482a0
-
Chow M, Newman JF, Filman D et al. Myristilation of picornavirus capsid protein VP4 and its structural significance. Nature 327, 482-486 (1987). (Pubitemid 17085817)
-
(1987)
Nature
, vol.327
, Issue.6122
, pp. 482-486
-
-
Chow, M.1
Newman, J.F.E.2
Filman, D.3
-
84
-
-
0024316730
-
Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus
-
Filman DJ, Syed RM, Chow M et al. Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus. EMBO J. 8, 1567-1579 (1989). (Pubitemid 19274384)
-
(1989)
EMBO Journal
, vol.8
, Issue.5
, pp. 1567-1579
-
-
Filman, D.J.1
Syed, R.2
Chow, M.3
Macadam, A.J.4
Minor, P.D.5
Hogle, J.M.6
-
85
-
-
0031172518
-
2
-
2 were able to reduce the interaction of poliovirus with water, hence contributing to thermostabilization
-
2 were able to reduce the interaction of poliovirus with water, hence contributing to thermostabilization.
-
(1997)
Arch. Biochem. Biophys.
, vol.342
, Issue.1
, pp. 108-116
-
-
Chen, C.H.1
Wu, R.2
Roth, L.G.3
-
86
-
-
0000165635
-
Cationic stabilization - A new property of enteroviruses
-
Wallis C, Melnick JL. Cationic stabilization - a new property of enteroviruses. Virology 16, 504-506 (1962).
-
(1962)
Virology
, vol.16
, pp. 504-506
-
-
Wallis, C.1
Melnick, J.L.2
-
87
-
-
0037203938
-
Thermostabilization of egg grown influenza virus
-
Important paper that demonstrates the ability of deuterium oxide to stabilize live-attenuated influenza A and B viruses grown in the allantoic cavity of embryonated eggs. This paper shows the possibility of increasing the potency of inactivated vaccine, which may partially degrade in the inimical environment of allantoic fluid by heavy water
-
Ikizler MR, Wright PF. Thermostabilization of egg grown influenza virus. Vaccine 20, 1393-1399 (2002). •• Important paper that demonstrates the ability of deuterium oxide to stabilize live-attenuated influenza A and B viruses grown in the allantoic cavity of embryonated eggs. This paper shows the possibility of increasing the potency of inactivated vaccine, which may partially degrade in the inimical environment of allantoic fluid by heavy water.
-
(2002)
Vaccine
, vol.20
, pp. 1393-1399
-
-
Ikizler, M.R.1
Wright, P.F.2
-
88
-
-
70449410278
-
-
PhD thesis submitted to deemed university Indian Veterinary Research Institute, Izatnagar, UP, India
-
2O). PhD thesis submitted to deemed university Indian Veterinary Research Institute, Izatnagar, UP, India (2009).
-
(2009)
2O)
-
-
Sen, A.1
-
89
-
-
0027985388
-
High diversity of poliovirus strains isolated from the central nervous system from patients with vaccine-associated paralytic poliomyelitis
-
Georgescu MM, Delpeyroux F, Tardy- Panit M et al. High diversity of poliovirus strains isolated from the central nervous system from patients with vaccine-associated paralytic poliomyelitis. J. Virol. 68(12), 8089-8101(1994). (Pubitemid 24362698)
-
(1994)
Journal of Virology
, vol.68
, Issue.12
, pp. 8089-8101
-
-
Georgescu, M.-M.1
Delpeyroux, F.2
Tardy-Panit, M.3
Balanant, J.4
Combiescu, M.5
Combiescu, A.A.6
Guillot, S.7
Crainic, R.8
-
91
-
-
70449459369
-
-
Children's Vaccine Initiative. Comprehensive review of all aspects of the practical uses of vaccines in children. The aspects of shelf life and thermal degradation are dealt with. The problems associated with adopting deuterium on a large scale are also mentioned
-
Children's Vaccine Initiative. Report of: Sixth Meeting Of The Advisory Committee. London, UK, 21-22 April 1994. • Comprehensive review of all aspects of the practical uses of vaccines in children. The aspects of shelf life and thermal degradation are dealt with. The problems associated with adopting deuterium on a large scale are also mentioned.
-
Report Of: Sixth Meeting of the Advisory Committee. London, UK, 21-22 April 1994
-
-
-
92
-
-
0007620692
-
-
WHO, Geneva, Switzerland Excellent treatise covering the major aspects of thermostability of vaccines. The degradation profiles and mechanisms of preventing thermal degradation using novel and conventional stabilizers are dealt with at length. The importance of vaccine vial monitors is also mentioned
-
Galazka A, Milstein J, Zaffran M. Thermostability of vaccines. Global programme for vaccines and immunizations. WHO, Geneva, Switzerland (1998). •• Excellent treatise covering the major aspects of thermostability of vaccines. The degradation profiles and mechanisms of preventing thermal degradation using novel and conventional stabilizers are dealt with at length. The importance of vaccine vial monitors is also mentioned.
-
(1998)
Thermostability of Vaccines. Global Programme for Vaccines and Immunizations
-
-
Galazka, A.1
Milstein, J.2
Zaffran, M.3
-
93
-
-
0142195888
-
Comparative efficacy of various chemical stabilizers on the thermostability of live attenuated peste des petits ruminants (PPR) vaccine
-
Brief account of the development of a live-attenuated peste des petits ruminants (PPR) vaccine. The comparative efficacies of conventional sugar-based stabilizers have been assessed, and thermostability studies on a live-attenuated PPR vaccine were performed. A pioneering effort in the field of thermostabilization of the PPR vaccine
-
Sarkar J, Sreenivasa BP, Singh RP et al. Comparative efficacy of various chemical stabilizers on the thermostability of live attenuated peste des petits ruminants (PPR) vaccine. Vaccine 21, 4728-4735 (2003). • Brief account of the development of a live-attenuated peste des petits ruminants (PPR) vaccine. The comparative efficacies of conventional sugar-based stabilizers have been assessed, and thermostability studies on a live-attenuated PPR vaccine were performed. A pioneering effort in the field of thermostabilization of the PPR vaccine.
-
(2003)
Vaccine
, vol.21
, pp. 4728-4735
-
-
Sarkar, J.1
Sreenivasa, B.P.2
Singh, R.P.3
-
94
-
-
0034666533
-
Current status of DNA vaccines in veterinary medicine
-
Rajendra KB. Current status of DNA vaccines in veterinary medicine. Adv. Drug Deliv. Rev. 43(1), 3-11 (2000).
-
(2000)
Adv. Drug Deliv. Rev.
, vol.43
, Issue.1
, pp. 3-11
-
-
Rajendra, K.B.1
-
95
-
-
0026045660
-
Storage and preservation of whole blood samples for use in detection of human immunodeficiency virus type-1 by the PCR
-
Kaye S, Loveday C, Tedder R. Storage and preservation of whole blood samples for use in detection of human immunodeficiency virus type-1 by the PCR. J. Virol. Methods 35, 217-226 (1991).
-
(1991)
J. Virol. Methods
, vol.35
, pp. 217-226
-
-
Kaye, S.1
Loveday, C.2
Tedder, R.3
-
96
-
-
33645022465
-
Single gene retrieval from thermally degraded DNA
-
Zhang L, Wu Q. Single gene retrieval from thermally degraded DNA. J. Biosci. 30(5), 599-604 (2005).
-
(2005)
J. Biosci.
, vol.30
, Issue.5
, pp. 599-604
-
-
Zhang, L.1
Wu, Q.2
-
97
-
-
0343569970
-
Rescue of infectious classical swine fever and foot-and-mouth disease virus by RNA transfection and virus detection by RT-PCR after extended storage of samples in Trizol
-
DOI 10.1016/S0166-0934(00)00154-3, PII S0166093400001543
-
Hofmann MA, Thur B, Liu L et al. Rescue of infectious classical swine fever and foot-and-mouth disease virus by RNA transfection and virus detection by RT-PCR after extended storage of samples in Trizol. J. Virol. Methods 87(1-2), 29-39 (2000). (Pubitemid 30345673)
-
(2000)
Journal of Virological Methods
, vol.87
, Issue.1-2
, pp. 29-39
-
-
Hofmann, M.A.1
Thur, B.2
Liu, L.3
Gerber, M.4
Stettler, P.5
Moser, C.6
Bossy, S.7
-
98
-
-
0034683141
-
Hygienic aspects of storage and use of semen for artificial insemination
-
DOI 10.1016/S0378-4320(00)00161-5, PII S0378432000001615
-
Thibier M, Guerin B. Hygienic aspects of storage and use of semen for artificial insemination. Anim. Reprod. Sci. 62(1-3), 233-251 (2000). (Pubitemid 30613276)
-
(2000)
Animal Reproduction Science
, vol.62
, Issue.1-3
, pp. 233-251
-
-
Thibier, M.1
Guerin, B.2
-
99
-
-
0036176495
-
Detection of equine arteritis virus by real-time TaqMan® reverse transcription-PCR assay
-
Balasuriya UBR, Christian M, Leutenegger JB et al. Detection of equine arteritis virus by real-time TaqMan® reverse transcription-PCR assay. J. Virol Methods 101(1-2), 21-28 (2002).
-
(2002)
J. Virol Methods
, vol.101
, Issue.1-2
, pp. 21-28
-
-
Balasuriya, U.B.R.1
Christian, M.2
Leutenegger, J.B.3
-
100
-
-
33645623344
-
Clinical results of neutron capture therapy
-
Harling OK, Bernard JA, Zamenhof RG (Eds). Pergamon Press, New York, USA and London, UK
-
Hatanaka H. Clinical results of neutron capture therapy. In: Neutron Beam Design, Development, and Performance for Neutron Capture Therapy (Basic Life Sciences volume 54). Harling OK, Bernard JA, Zamenhof RG (Eds). Pergamon Press, New York, USA and London, UK, 15-21 (1989).
-
(1989)
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy (Basic Life Sciences Volume 54)
, pp. 15-21
-
-
Hatanaka, H.1
-
101
-
-
0002113197
-
The isolation of deuterated bacteriorhodopsin from fully deuterated Halobacterium halobium
-
Crespi HL. The isolation of deuterated bacteriorhodopsin from fully deuterated Halobacterium halobium. Methods Enzymol. 88, 3-5 (1982).
-
(1982)
Methods Enzymol.
, vol.88
, pp. 3-5
-
-
Crespi, H.L.1
-
102
-
-
0027519297
-
Low cost production of perdeuterated biomass using methylotrophic yeasts
-
DOI 10.1002/jlcr.2580331108
-
Haon S, Auge S, Tropis M et al. Low cost production of perdeuterated biomass using methylotrophic yeasts. J. Labelled Comp. Radiopharmaceuticals 22, 1053-1063 (1993). (Pubitemid 23317713)
-
(1993)
Journal of Labelled Compounds and Radiopharmaceuticals
, vol.33
, Issue.11
, pp. 1053-1063
-
-
Haon, S.1
Auge, S.2
Tropis, M.3
Milon, A.4
Lindley, N.C.5
-
104
-
-
0027101463
-
Deuterium in North Atlantic storm tops
-
Smith RB. Deuterium in North Atlantic storm tops. J. Atmos. Sci. 49, 2041-2057 (1992).
-
(1992)
J. Atmos. Sci.
, vol.49
, pp. 2041-2057
-
-
Smith, R.B.1
-
105
-
-
0023509497
-
Vostok ice core: A continuous isotope temperature record over the last climatic cycle (160 000 years)
-
DOI 10.1038/329403a0
-
Jouzel J, Lorius C, Petit JR et al. Vostok ice core: a continuous isotope temperature record over the last climatic cycle (160,000 years). Nature 329, 403-408(1987). (Pubitemid 18317444)
-
(1987)
Nature
, vol.329
, Issue.6138
, pp. 403-408
-
-
Jouzel, J.1
-
106
-
-
0024901540
-
Covariance of oxygen and hydrogen isotopic compositions in plant water: Species effects
-
Cooper LW, DeNiro MJ. Covariance of oxygen and hydrogen isotopic compositions in plant water: species effects. Ecology 70, 1619-1628 (1989).
-
(1989)
Ecology
, vol.70
, pp. 1619-1628
-
-
Cooper, L.W.1
Deniro, M.J.2
-
107
-
-
0022175539
-
Dendroclimatological implications of isotope coherence in trees from Kashmir Valley, India
-
Ramesh R, Bhattacharya SK, Gopalan K. Dendroclimatological implications of isotope coherence iri trees from Kashmir Valley, India. Nature 317, 802-804 (1985). (Pubitemid 17269084)
-
(1985)
Nature
, vol.317
, Issue.6040
, pp. 802-804
-
-
Ramesh, R.1
Bhattacharya, S.K.2
Gopalan, K.3
-
108
-
-
70449446247
-
First results from the measurement of the distribution of water in building concrete by means of MRI (magnetic resonance imaging) and x-ray computer tomography
-
Kaufmann J, Luethi T, Flisch A et al. First results from the measurement of the distribution of water in building concrete by means of MRI (magnetic resonance imaging) and x-ray computer tomography. Proceedings of the DGZFP Annual Meeting, Innovative Nondestructive Testing - A Challenge to all Sectors of Industry. Fulda, Germany, 27-29 April 1992.
-
Proceedings of the DGZFP Annual Meeting, Innovative Nondestructive Testing - a Challenge to All Sectors of Industry. Fulda, Germany, 27-29 April 1992
-
-
Kaufmann, J.1
Luethi, T.2
Flisch, A.3
-
109
-
-
0027486276
-
Inhibitory effects of deuterium substitutuion on the metabolism of sevoflurane by the rat
-
Baker MT, Ronnenberg WC Jr, Ruzicka JA et al. Inhibitory effects of deuterium substitutuion on the metabolism of sevoflurane by the rat. Drug Metab. Dispos. 21, 1170-1171 (1993).
-
(1993)
Drug Metab. Dispos.
, vol.21
, pp. 1170-1171
-
-
Baker, M.T.1
Ronnenberg Jr., W.C.2
Ruzicka, J.A.3
-
110
-
-
0014122517
-
Efficacies of vaccines containing alginate adjuvant
-
Shapiro A, Modai Y, Kohn A. Efficacies of vaccines containing alginate adjuvant. J. Appl. Bacteriol. 30(2), 304-311 (1967).
-
(1967)
J. Appl. Bacteriol.
, vol.30
, Issue.2
, pp. 304-311
-
-
Shapiro, A.1
Modai, Y.2
Kohn, A.3
-
111
-
-
3042545117
-
Isothermal desiccation and vitrification kinetics of trehalosedextran solutions
-
Aksan A, Toner M. Isothermal desiccation and vitrification kinetics of trehalosedextran solutions. Langmuir 20, 5521-5529 (2004).
-
(2004)
Langmuir
, vol.20
, pp. 5521-5529
-
-
Aksan, A.1
Toner, M.2
-
114
-
-
70449399910
-
-
TEVA PHARM. INDUSTRIES, LTD: EP-332826
-
TEVA PHARM. INDUSTRIES, LTD: EP-332826 (1989).
-
(1989)
-
-
-
115
-
-
70449451443
-
-
BOEHRINGER SOHN CH CMBH: DE2516836
-
BOEHRINGER SOHN CH CMBH: DE2516836 (1976).
-
(1976)
-
-
-
116
-
-
70449438735
-
-
Patent US5223269
-
Liepins A: Patent US5223269 (1993).
-
(1993)
-
-
Liepins, A.1
-
119
-
-
70449437379
-
-
MERCK AND CO., INC: US4028405
-
MERCK AND CO., INC: US4028405 (1977).
-
(1977)
-
-
-
120
-
-
70449414500
-
-
Accessed 16 February 2006
-
Heavy water in depth www.sircuitskin.com/heavy-water (Accessed 16 February 2006)
-
Heavy Water in Depth
-
-
|