Effects of chitosan pentamer and chitosan hexamer in vivo and in vitro on gene expression and secretion of cytokines

Food and Agricultural Immunology

Volumn 20, Issue 3, 2009, Pages 269-280

  Wei, Xinlin ^a   Wang, Yuanfeng ^a   Zhu, Qing ^b   Xiao, Jianbo ^a   Xia, Wenshui ^c  

^a SHANGHAI NORMAL UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

^c JIANGNAN UNIVERSITY   (China)

Author keywords

Chitosan hexamer; Chitosan pentamer; Cytokines; Gene expression; Secretion

Indexed keywords

EID: 70449407291     PISSN: 09540105     EISSN: 14653443     Source Type: Journal    
DOI: 10.1080/09540100903168157     Document Type: Article

References (32)

1. Butler, D.M., Maini, R.N., Feldmann, M., & Brennan, F.M. (1995). Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. European Cytokine Network, 6, 225-230.
2. Denis, M., & Ghadirian, E. (1994). Interleukin-1 is involved in mouse resistance toMycobacterium avium. Infection and Immunity, 62, 457-461.
3. Du, L.G., Bai, X.F., & Jin, Z.L. (2002). Study on antitumor effect of chitooligosaccharides. Chinese Marine Drug, 86, 18-21.
4. Feng, J., Zhao, L.H., & Yu, Q.Q. (2004). Receptor-mediated stimulatory effect of oligochitosan in macrophages. Biochemical and Biophysical Research Communications, 317,414-420.
5. Fujihara, M., Ito, N., Pace, J.L., Watanabe, Y., Russell, S.W., & Suzuki, T. (1994). Role of endogenous interferon-beta in lipopolysaccharide-triggered activation of the inducible nitric-oxide synthase gene in a mouse macrophage cell line, J774. Journal of Biological Chemistry, 269, 12773-12778.
6. Gorbach, V.I., Krasikova, I.N., Luk'yanov, P.A., Loenko, Y.N., Solov'eva, T.F., Ovodov, Y.S., et al. (1994). New glycolipids (chitooligosaccharide derivatives) possessing immunostimulating and antitumor activities. Carbohydrate Research, 260, 73-82.
7. Je, J.Y., Park, P.J., & Kim, S.K. (2004). Free radical scavenging properties of hetero-chitooligosaccharides using an ESR spectroscopy. Food and Chemical Toxicology, 42, 381-387.
8. Jeon, Y.J., & Kim, S.K. (2001). Potential immuno-stimulating effect of antitumoral fraction of chitosan oligosaccharides. Journal of Chitin and Chitosan, 6, 163-167.
9. Jeon, Y.J., & Kim, S.K. (2002). Antitumor activity of chitosan oligosaccharides produced in ultrafiltration membrane reactor system. Journal of Microbiology and Biotechnology, 12, 503-507.
10. Jeon, Y.J., Shahidi, F., & Kim, S.K. (2000). Preparation of chitin and chitosan chitooligosaccharides and their applications in physiological functional foods. Food Reviews International, 16, 159-176.
11. Kendra, D.F., Christian, D., & Hadwiger, L.A. (1989). Chitosan oligomers from Fusarium solani/pea interactions, chitinase/b-glucanase digestion of sporelings and from fungal wall chitin actively inhibit fungal growth and enhance disease resistance. Physiological and Molecular Plant Pathology, 35, 215-230.
12. Kendra, D.F., & Hadwiger, L.A. (1984). Characterization of the smallest chitosan oligomer that is maximally antifungal to Fusarium solani and elicits posatin formation in Pisum sativum. Experimental Mycology, 8, 276-281.
13. Le, J., Prensky, W., Yip, Y.K., Chang, Z., Hoffman, T., Stevenson, H.C., et al. (1983). Activation of human monocyte cytotoxicity by natural and recombinant immune interferon. Journal of Immunology, 131, 2821-2826.
14. Nathan, C.F., Murray, H.W., Wiebe, M.E., & Rubin, B.Y. (1983). Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. Journal of Experimental Medicine, 158, 670-689.
15. Pace, J.L., Russell, S.W., Torres, B.A., Johnson, H.M., & Gray, P.W. (1983). Recombinant mouse gamma interferon induces the priming step in macrophage activation for tumor cell killing. Journal of Immunology, 130, 2011-2013.
16. Park, P.J., Je, J.Y., Byun, H.G., Moon, S.H., & Kim, S.K. (2004). Antimicrobial activity of hetero-chitosans and their oligosaccharides with different molecular weights. Journal of Microbiology and Biotechnology, 14, 317-323.
17. Robertson, M.J., & Ritz, J. (1990). Biology and clinical relevance of human natural killer cells. Blood, 76, 2421-2438.
18. Rogers, H.W., Tripp, C.S., Schreiber, R.D., & Unanue, E.R. (1994). Endogenous IL-1 is required for neutrophil recruitment and macrophage activation during murine listeriosis. Journal of Immunology, 53, 2093-2101.
19. Ruan, Z., Fu, X.F., Zhou, Q.C., Hu, X.B., & Wu, M.C. (2006). Effect of polysaccharide L-2 from lentinus edodes on TNF-a and IL-2. Food Science, 27, 223-226.
20. Shibata, Y., Foster, L.A., Kurimoto, M., Okamura, H., Nakamura, R.M., Kawajiri, K., et al. (1998). Immunoregulatory roles of IL-10 ininnate immunty: IL-10 inhibits macrophage production of IFN-gamma-inducing factors but enhances NK cell production of IFN-gamma. Journal of Immunology, 161, 4283-4288.
21. Shibata, Y., Foster, L.A., Metzger, W.J., & Myrvik, Q.N. (1997). Alveolar macrophage priming by intravenous administration of chitin particels, polymers of N-acetyl-D-glucosamine in mice. Infection and Immunity, 65, 1734-1741.
22. Shibata, Y., Honda, I., Justice, J.P., Scott, M.R.V., Nakamura, R.M., & Myrvik, Q.N. (2001). Th1 adjuvant N-acetyl-D-glucosamine polymer up-regulates Thl immunity but down-regulates Th2 immunity against a mycobacterial protein (MPB-59) in interleukin-10-knockout and wild-type mice. Infection and Immunity, 69, 6123-6130.
23. Suzuki, K., Mikami, T., Okawa, Y., Tokoro, A., Suzuki, S., & Suzuki, M. (1986). Antitumor effect of hexa-N-acetylchitohexaose and chitohexaose. Carbohydrate Research, 151, 403-408.
24. Tokoro, A., Kobayashi, M., Tatewaki, N., Suzuki, K., Okawa, Y., Mikami, T., et al. (1989). Protective effect of N-acetyl-chito-hexaose on Listeria monocytogenes infection in mice. Microbiology and Immnology, 33, 357-367.
25. Tokoro, A., Suzuki, K., Matsumoto, T., Mikami, T., Suzuki, S., & Suzuki, M. (1988). Chemotactic response of human neutrophils to N-cetyl chitohexaose in vitro. Microbiology and Immunology, 32, 387.
26. Toribio, M.L., de la Hera, A., Borst, J., Marcos, M.A., Marquez, C., Alonso, J.M., et al. (1988). Involvement of the interleukin 2 pathway in the rearrangement and expression of both alpha/beta and gamma/delta T cell receptor genes in human T cell precursors. Journal of Experimental Medicine, 168, 2231-2249.
27. Tracey, K.J., Fong, Y., Hesse, D.G., Manogue, K.R., Lee, A.T., Kuo, G.C., et al. (1987). Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature, 330, 662-664.
28. Tsukada, K., Matsumoto, T., Aizawa, K., Tokoro, A., Naruse, R., & Suzuki, S., et al. (1990). Antimetastatic and growth-inhibitory effects of N-acetylchitohexaose in mice bearing Lewis lung carcinoma. Japanese Journal of Cancer Research, 81, 259-265.
29. Wang, F.Y., & He, Y.S. (2001). Study on antitumor effect of water-soluble chitosan. Journal of Chinese Biochemical Drug, 22, 21-22.
30. Wu, G.J., & Tsai, G.J. (2004). Cellulase degradation of shrimp chitosan for the preparation of a water-soluble hydrolysate with immunoactivity. Fisheries Science, 70, 1113-1120.
31. Xia, W.S. (2001). Advance in enzymatic modification of chitosan. Journal of Wuxi University of Light Industry, 20, 550-554.
32. Zhan, Y., & Cheers, C. (1995). Differential induction of macrophage-derived cytokines by live and dead intracellular bacteria in vitro. Infection and Immunology, 63, 720-727.