Antimycobacterial activity of exocarpos latifolius is due to exocarpic acid

Planta Medica

Volumn 75, Issue 12, 2009, Pages 1326-1330

  Koch, Michael ^a   Bugni, Tim S ^a   Pond, Chris D ^a   Sondossi, Mohammad ^b   Dindi, Manah ^c   Piskaut, Pius ^c   Ireland, Chris M ^a   Barrows, Louis R ^a  

^a UNIVERSITY OF UTAH   (United States)

^b WEBER STATE UNIVERSITY   (United States)

^c UNIVERSITY OF PAPUA NEW GUINEA   (Papua New Guinea)

Author keywords

Exocarpic acid; Exocarpos latifolius; Mycobacterium tuberculosis; Polyacetylenic fatty acids; Santalaceae

Indexed keywords

15 HYDROXYOCTADECA 13 ENE 9,11 DIYNOIC ACID; 15 OXO OCTADECA 13 ENE 9,11 DIYNOIC ACID; 8 HYDROXYOCTADECA 13 ENE 9,11 DIYNOIC ACID; ANTIMYCOBACTERIAL AGENT; EXOCARPIC ACID; ISONIAZID; OCTADECA 13 ENE 9,11 DIYNOIC ACID GLYCEROL ESTER; OCTADECA 13 ENE 9,11 TRIENOIC ACID; PLANT EXTRACT; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; DRUG POTENTIATION; DRUG STRUCTURE; ENTEROCOCCACEAE; ESCHERICHIA COLI; EXOCARPOS LATIFOLIUS; MEDICINAL PLANT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIA;

ANTI-BACTERIAL AGENTS; CHEMICAL FRACTIONATION; DIYNES; FATTY ACIDS, UNSATURATED; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PLANT EXTRACTS; SANTALACEAE;

EXOCARPOS; MYCOBACTERIUM TUBERCULOSIS; NEGIBACTERIA; POSIBACTERIA; SANTALACEAE;

EID: 70449372412     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1185687     Document Type: Article

References (19)

1. International Cooperative Biodiversity Groups (ICBG). Available at http://www.fic.nih.gov/programs/research-grants/icbg/. Accessed October 15, 2008
2. TB Country Profile Papua New Guinea. Available at http://www.who.int/ globalatlas/predefinedReports/TB/PDF-Files/png.pdf. Accessed October 15, 2008
3. El-Jaber NA, Estevez-Braun AG, Munoz-Munoz RO, Rodriguez-Alfonso A, Murguia JR. Acetylenic acids from the aerial parts of Nanodea muscos. J Nat Prod 2003; 66: 722-724
4. Naidoo LAC, Drewes SE, Van Staden J, Hutchings A. Exocarpic acid and other compounds from tubers and inflorescences of Sarcophyte sanguinea. Phytochemistry 1992; 31: 3929-3931
5. Li X-C, Jacob MR, Khan SI, Ashfaq MK, Babu KS, Agarwal AK, El Sohly HN, Manly SP, Clark AM. Potent in vitro antifungal activities of naturally occurring acetylenic acids. Antimicrob Agents Chemother 2008; 52: 2442-2448
6. Zgoda JR, Freyer AJ, Killmer LB, Porter JR. Polyacetylene carboxylic acids from Mitrephora celebica. J Nat Prod 2001; 64: 1348-1349
7. Kobaisy M, Abramowski Z, Lermer L, Saxena G, Hancock REW, Towers GHN. Antimycobacterial polyynes of Devil's club (Oplopanax horridus), a North American native medicinal plant. J Nat Prod 1997; 60: 1210-1213
8. Naidoo LAC, Drewes SE, Drewes FE, Van Staden J, Aken ME. When is a parasite no longer a parasite? The case of Sarcophyte sanguinea and exocarpic acid. South African J Sci 1994; 90: 359-361
9. Franzblau SG,Witzig RS,McLaughlin JC, Torres P, Madico G, Hernandez A, DegnanMT, Cook MB, Quenzer VK, Ferguson RM, Gilman RH. Rapid, lowtechnology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate alamar blue assay. J Clin Microbiol 1998; 36: 362-366
10. Foongladda S, Roengsanthia D, Arjrattanakool W, Chuchottaworn C, Chaiprasert A, Franzblau SG. Rapid and simple MTT method for rifampicin and isoniazid susceptibility testing of Mycobacterium tuberculosis. Int J Tuberc Lung Dis 2002; 6: 1118-1122
11. Ferraro MJ, Craig WA, Dudley MN, Eliopoulos GM, Hecht DW, Hindler J, Reller LB, Shelodon AT, Swenson JM, Tenover FC, Testa RT, Weinstein MP, Wikler MA. Methods for dilution antimicrobial susceptibility tests for bacteria that growaerobically; approved standard, 5th edition.Wayne: NCCLS; 2000
12. Amakura Y, Kondo K, Akiyama H, Ito H, Hatano T, Yoshida T, Tamio M. Characteristic long-chain fatty acid of Pleurocybella porrigens. J Food Hyg Soc Jap 2006; 47: 178-181 (Pubitemid 44433280)
13. Badami RC, Gunstone FD. Vegetable oils. XIII - The component acids of isano (boleko) oil. J Sci Food Agric 1963; 14: 863-866
14. The Tuberculosis Antimicrobial Acquisition and Coordinating Facility. Available at http://www.taacf.org. Accessed October 15, 2008
15. Collins, LA, Franzblau SG. Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium. Antimicrob Agents Chemother 1997; 41: 1004-1009
16. Cho HS, Warit S, Wan B, Hwang CH, Pauli GE, Franzblau SG. Low oxygen recovery assay (LORA) for high throughput screening of compounds against non-replicating Mycobacterium tuberculosis. Antimicrob Agents Chemother 2007; 51: 1380-1385
17. Morbidoni C, Vilchèze L, Kremer R, Bittman J, Sacchettini W, Jacobs JR. Dual inhibition of mycobacterial fatty acid biosynthesis and degradation by 2-alkynoic acids. Chem Biol 2006; 13: 297-307
18. Wu L, Liu Z, Li D. Oct-2-yn-4-enoyl-CoA as a multifunctional enzyme inhibitor in fatty acid oxidation. Org Lett 2008; 10: 2235-2238
19. Ondeyka J, Zink D, Young K, Painter R, Kodali S, Galgoci A, Collado J, Tormo JR, Basilio A, Vicente F, Wang J, Singh SB. Discovery of bacterial fatty acid synthase inhibitors from a Phoma species as antimicrobial agents using a new antisense-based strategy. J Nat Prod 2006; 69: 377-380