Experimental investigation of bubble formation in a microfluidic T-shaped junction

Nanoscale and Microscale Thermophysical Engineering

Volumn 13, Issue 4, 2009, Pages 228-242

  Zhang, Yuxiang ^a   Wang, Liqiu ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Bubble; Fluid mechanics; Microfluidics; T shaped junction; Visualization

Indexed keywords

BUBBLE; BUBBLE VOLUME; CAPILLARY NUMBERS; EMPIRICAL RELATIONS; EXPERIMENTAL INVESTIGATIONS; GAS INLET; GLASS MICROFLUIDIC DEVICES; LIQUID FLOW RATES; LIQUID PRESSURE; LIQUID VISCOSITY; T-SHAPED JUNCTION;

BUBBLE FORMATION; BUBBLES (IN FLUIDS); CAPILLARITY; CONTACTS (FLUID MECHANICS); INDOOR AIR POLLUTION; LIQUIDS; MECHANICS; PRESSURE DROP; SURFACE TENSION; VISCOSITY; VISUALIZATION;

MICROFLUIDICS;

EID: 70449350438     PISSN: 15567265     EISSN: None     Source Type: Journal    
DOI: 10.1080/15567260903276999     Document Type: Article

References (36)

1. R. Bekeredjian, P.A. Grayburn, and R.V. Shohet, Use of Ultrasound Contrast Agents for Gene or Drug Delivery in Cardiovascular Medicine, Journal of the American College of Cardiology, vol.45, pp. 329-335, 2005.
2. C.W. Lewis, J. McConaughy,D. Rinkevich, A.L.Klibanov, and J.R. Lindner, Development of a Novel Microbubble Agent for Ultrasound-Mediated Targeted Drug Delivery, Circulation, vol.110, pp. 511-1511, 2004.
3. J.G. Riess, Fluorocarbon-Based Injectable Gaseous Microbubbles for Diagnosis and Therapy, Current Opinion in Colloid & Interface Science, vol.8, pp. 259-266, 2003.
4. M. De Menech, P. Garstecki, F. Jousse, and H.A. Stone, Transition from Squeezing to Dripping in a Microfluidic T-Shaped Junction, Journal of Fluid Mechanics, vol.595, pp. 141-161, 2008.
5. P. Garstecki, M.J. Fuerstman, H.A. Stone, and G.M. Whitesides, Formation of Droplets and Bubbles in a Microfluidic T-Junction-Scaling and Mechanism of Break-Up, Lab on a Chip, vol.6, pp. 437-446, 2006.
6. J. Husny and J.J. Cooper-White, The Effect of Elasticity on Drop Creation in T-Shaped Microchannels, Journal of Non-Newtonian Fluid Mechanics, vol.137, pp. 121-136, 2006.
7. D.R. Link, S.L. Anna, D.A. Weitz, and H.A. Stone, Geometrically Mediated Breakup of Drops inMicrofluidicDevices, Physical Review Letters, vol.92, pp. 054503.1-054503.4, 2004.
8. D.Y. Qian and A. Lawal, Numerical Study on Gas and Liquid Slugs for Taylor Flow in a TJunction Microchannel, Chemical Engineering Science, vol.61, pp. 7609-7625, 2006.
9. T. Thorsen, R.W. Roberts, F.H. Arnold, and S.R. Quake, Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device, Physical Review Letters, vol.86, pp. 4163-4166, 2001.
10. J.D. Tice, A.D. Lyon, and R.F. Ismagilov, Effects of Viscosity on Droplet Formation and Mixing in Microfluidic Channels, Analytica Chimica Acta, vol.507, pp. 73-77, 2004.
11. S. Van Der Graaf, T. Nisisako, C. Schroen, R.G.M. Van Der Sman, and R.M. Boom, Lattice Boltzmann Simulations of Droplet Formation in a T-Shaped Microchannel, Langmuir, vol.22, pp. 4144-4152, 2006.
12. S. Van Der Graaf, M.L.J. Steegmans, R.G.M. Van Der Sman, C. Schroen, and R.M. Boom, Droplet Formation in a T-Shaped Microchannel Junction: A Model System for Membrane Emulsification, Colloids and Surfaces A - Physicochemical and Engineering Aspects, vol.266, pp. 106-116, 2005.
13. J.H. Xu, S.W. Li, J. Tan, Y.J. Wang, and G.S. Luo, Preparation of Highly Monodisperse Droplet in a T-Junction Microfluidic Device, AIChE Journal, vol.52, pp. 3005-3010, 2006. (Pubitemid 44368684)
14. J.H. Xu, S.W. Li, J. Tan, Y.J. Wang, and G.S. Luo, Controllable Preparation of Monodisperse O/W and W/O Emulsions in the Same Microfluidic Device, Langmuir, vol.22, pp. 7943-7946, 2006.
15. J.H. Xu, S.W. Li, Y.J. Wang, and G.S. Luo, Controllable Gas-Liquid Phase Flow Patterns and Monodisperse Microbubbles in a Microfluidic T-Junction Device, Applied Physics Letters, vol.88, pp. 133506.1-133506.3, 2006.
16. S.L. Anna, N. Bontoux, and H.A. Stone, Formation of Dispersions Using ''Flow Focusing'' in Microchannels, Applied Physics Letters, vol.82, pp. 364-366, 2003.
17. A.M. Ganan-Calvo, Perfectly Monodisperse Microbubbling by Capillary Flow Focusing: An Alternate Physical Description and Universal Scaling, Physical Review E, vol.69, pp. 027301.1-027301.3, 2004.
18. A.M. Ganan-Calvo and J.M. Gordillo, Perfectly Monodisperse Microbubbling by Capillary Flow Focusing, Physical Review Letters, vol.87, pp. 274501.1-274501.4, 2001.
19. P. Garstecki, I. Gitlin, W. DiLuzio, G.M. Whitesides, E. Kumacheva, and H.A. Stone, Formation of Monodisperse Bubbles in a Microfluidic Flow-Focusing Device, Applied Physics Letters, vol.85, pp. 2649-2651, 2004.
20. P. Garstecki, H.A. Stone, and G.M. Whitesides, Mechanism for Flow-Rate Controlled Breakup in Confined Geometries: A Route to Monodisperse Emulsions, Physical Review Letters, vol.94, pp. 164501.1-164501.4, 2005.
21. L.Y. Chu, A.S. Utada, R.K. Shah, J.W. Kim, and D.A. Weitz, Controllable Monodisperse Multiple Emulsions, Angewandte Chemie International Edition, vol.46, pp. 8970-8974, 2007.
22. R.K. Shah, H.C. Shum, A.C. Rowat, D. Lee, J.J. Agresti, A.S. Utada, L.Y. Chu, J.W. Kim, A. Fernandez-Nieves, C.J. Martinez, and D.A. Weitz, Designer Emulsions Using Microfluidics, Materials Today, vol.11, pp. 18-27, 2008.
23. A.S. Utada, E. Lorenceau, D.R. Link, P.D. Kaplan, H.A. Stone, and D.A. Weitz, Monodisperse Double Emulsions Generated from a Microcapillary Device, Science, vol.308, pp. 537-541, 2005.
24. G.F. Christopher and S.L. Anna, Microfluidic Methods for Generating Continuous Droplet Streams, Journal of Physics D - Applied Physics, vol.40, pp. R319-R336, 2007.
25. J.H. Xu, G.S. Luo, G.G. Chen, and J.D. Wang, Experimental and Theoretical Approaches on Droplet Formation from a Micrometer Screen Hole, Journal of Membrane Science, vol.266, pp. 121-131, 2005.
26. G.F. Christopher, N.N. Noharuddin, J.A. Taylor, and S.L. Anna, Experimental Observations of the Squeezing-to-Dripping Transition in T-Shaped Microfluidic Junctions, Physical Review E, vol.78, pp. 036317.1-036317.12, 2008.
27. P. Guillot and A. Colin, Stability of Parallel Flows in a Microchannel after a T Junction, Physical Review E, vol.72, pp. 066301.1-066301.4, 2005.
28. L.Q. Wang, Y.X. Zhang, and L. Cheng, Magic Microfluidic T-Junctions: Valving and Bubbling, Chaos Solitons & Fractals, vol.39, pp. 1530-1537, 2009.
29. L.X. Chen, G.A. Luo, K.H. Liu, J.P. Ma, B. Yao, Y.C. Yan, and Y.M. Wang, Bonding of Glass-Based Microfluidic Chips at Low- or Room-Temperature in Routine Laboratory, Sensors and Actuators B - Chemical, vol.119, pp. 335-344, 2006.
30. N. Nam-Trung and S.T. Wereley, Fundamentals and Applications of Microfluidics, Artech House, Boston, 2002.
31. N.A. Joseph and H. Spurk, Fluid Mechanics, 2nd ed., Springer, Berlin, 2008.
32. F.M. White, Fluid Mechanics, 4th Ed., WCB/McGraw-Hill, Boston, 1999.
33. C.J. Morris and F.K. Forster, Oscillatory Flow in Microchannels- Comparison of Exact and Approximate Impedance Models with Experiments, Experiments in Fluids, vol.36, pp. 928-937, 2004.
34. M.J. Fuerstman, A. Lai, M.E. Thurlow, S.S. Shevkoplyas, H.A. Stone, and G.M. Whitesides, The Pressure Drop along Rectangular Microchannels Containing Bubbles, Lab on a Chip, vol.7, pp. 1479-1489, 2007.
35. G. Croce, P. D'Agaro, and C. Nonino, Three-Dimensional Roughness Effect on Microchannel Heat Transfer and Pressure Drop, International Journal of Heat and Mass Transfer, vol.50, pp. 5249-5259, 2007.
36. Y.D. Hu, C. Werner, and D.Q. Li, Influence of Three-Dimensional Roughness on Pressure- Driven Flow through Microchannels, Journal of Fluids Engineering - Transactions of the ASME, vol.125, pp. 871-879, 2003.