Enantioselective esterification of ibuprofen with ethanol as reactant and solvent catalyzed by immobilized lipase: Experimental andmolecular modeling aspects

Journal of Chemical Technology and Biotechnology

Volumn 84, Issue 10, 2009, Pages 1461-1473

  Foresti, María L ^a,b   Galle, Marianela ^a   Ferreira, María L ^b   Briand, Laura E ^a  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b PLAPIQUI UNS CONICET   (Argentina)

Author keywords

Enantioselective; Esterification; Ibuprofen; Lipase; Molecular modeling

Indexed keywords

CONCENTRATION OF; COSOLVENTS; ENANTIOMERIC EXCESS; ENANTIOSELECTIVE; ENANTIOSELECTIVE ESTERIFICATION; ENZYMATIC ESTERIFICATION; ETHYL ESTERS; EXPERIMENTAL DATA; HIGH CONCENTRATION; IBUPROFEN; IMMOBILIZED LIPASE; MODELING ASPECTS; MOLAR RATIO; NOVOZYM435; OPTIMUM CONDITIONS; RACEMIC MIXTURES; REACTION MEDIA;

DRUG PRODUCTS; ENZYME INHIBITION; ESTERIFICATION; ESTERS; ETHANOL; LIPASES; MOLECULAR MODELING; PARAFFINS;

ORGANIC SOLVENTS;

ALCOHOL; ESTER DERIVATIVE; IBUPROFEN; ORGANIC COMPOUND; SOLVENT; TRIACYLGLYCEROL LIPASE; WATER;

ARTICLE; BATCH REACTOR; CATALYSIS; DRUG STRUCTURE; ENANTIOSELECTIVITY; ENZYME IMMOBILIZATION; ENZYME INHIBITION; ESTERIFICATION; MOLECULAR MODEL; RACEMIC MIXTURE;

EID: 70449344261     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.2200     Document Type: Article

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