Enantioselective esterification of racemic ibuprofen in isooctane by immobilized lipase on cellulose acetate-titanium iso-propoxide gel fiber

Journal of Bioscience and Bioengineering

Volumn 93, Issue 1, 2002, Pages 98-100

  Ikeda, Yuko ^a   Kurokawa, Youichi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Candida rugosa; Enantioselective esterification; Entrap immobilization; Fiber; Ibuprofen

Indexed keywords

ALCOHOLS; CELLULOSE; ESTERS; SOL-GELS;

ENANTIOSELECTIVE;

ENZYME IMMOBILIZATION;

CELLULOSE ACETATE; ESTER; IBUPROFEN; IMMOBILIZED ENZYME; OCTANE; OXIDE; PROPANOL; TITANIUM; TRIACYLGLYCEROL LIPASE;

ARTICLE; BIOCATALYST; CANDIDA RUGOSA; CHEMICAL REACTION; DRUG SYNTHESIS; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; ESTERIFICATION; FIBER; GEL; NONHUMAN; RACEMIC MIXTURE;

CANDIDA; CANDIDA RUGOSA;

EID: 0036185436     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(02)80062-7     Document Type: Article

References (17)

1. Ester synthesis in lipase-catalyzed reactions
2. Biotransformations with lipases
3. Lipases in racemic resolutions
4. Lipase-supported synthesis of biologically active compounds
5. Enzymatic synthesis of (S)-ibuprofen ester prodrug from racemic ibuprofen by lipase in organic solvents
6. Influence of water activity on the enantioselective esterification of (R,S)-ibuprofen by Candida antarctica lipase B in solventless media
7. Highly enantioselective esterification of racemic ibuprofen in a packed bed reactor using immobilised Rhizomucor miehei lipase
8. Natural and synthetic carriers suitable for immobilization of viable cells, active organelles, and molecules
9. Bioreactors with immobilized lipases: State of the art
10. Optimizing lipase activity, enantioselectivity, and stability with medium engineering and immobilization for β-blocker synthesis
11. Kinetic resolution of 1-phenyl ethanol with high enantioselectivity with native and immobilized lipase in organic solvents
12. Efficient immobilization of lipases by entrapment in hydrophobic solgel materials
13. Biochemical engineering of biocatalysts immobilized on cellulosic materials
14. Adsorption and enzyme (β-galactosidase and α-chymotrypsin): Immobilization properties of gel fibre prepared by the gel formation of cellulose acetate and titanium iso-propoxide
15. Quantitative analysis of biochemical kinetic resolutions of enantiomers
16. High enantioselective esterification of 2-arylpropionic acids catalyzed by immobilized lipase from Candida antarctica: A mechanical approach
17. Lipase-catalyzed enantioselective esterification of ibuprofen in organic solvents under controlled water activity