Osteosarcoma in Preadolescent Patients: Experience in a Single Institute in Taiwan

Journal of the Chinese Medical Association

Volumn 72, Issue 9, 2009, Pages 455-461

  Hsieh, Ming Yun ^a,c   Hung, Giun Yi ^b,c   Yen, Hsiu Ju ^b,c   Chen, Wei Ming ^b,c   Chen, Tain Hsiung ^b,c  

^a FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

adolescent; osteosarcoma; preadolescent

Indexed keywords

ALKALINE PHOSPHATASE; CISPLATIN; DOXORUBICIN; EPIRUBICIN; IFOSFAMIDE; METHOTREXATE;

ALKALINE PHOSPHATASE BLOOD LEVEL; ARTHRODESIS; ARTICLE; BONE METASTASIS; BONE SCINTISCANNING; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER SURGERY; CANCER SURVIVAL; CHILD; CHILDHOOD CANCER; CLINICAL FEATURE; CONTROLLED STUDY; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FEMUR; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HUMERUS; INTESTINE INTUSSUSCEPTION; INTESTINE TUMOR; LIMB SALVAGE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MICROMETASTASIS; MULTIPLE CYCLE TREATMENT; OSTEOSARCOMA; OVERALL SURVIVAL; PATHOLOGIC FRACTURE; PREPUBERTY; PRESCHOOL CHILD; PRIMARY TUMOR; PROGNOSIS; SCHOOL CHILD; SEPTIC SHOCK; SEX RATIO; SURVIVAL RATE; TAIWAN; TIBIA; TUMOR GROWTH; TUMOR LOCALIZATION; TUMOR NECROSIS;

ADOLESCENT; AGE FACTORS; ALKALINE PHOSPHATASE; BONE NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; MALE; OSTEOSARCOMA; SURVIVAL RATE;

EID: 70449331506     PISSN: 17264901     EISSN: 17287731     Source Type: Journal    
DOI: 10.1016/S1726-4901(09)70407-1     Document Type: Article

References (27)

1. st decade of life: retrospective survey of biopsy results. Radiology 160 (1986) 491-495
2. Scranton Jr. P.E., DeCicco F.A., Totten R.S., and Yunis E.J. Prognostic factors in osteosarcoma: a review of 20 years at the University of Pittsburg Health Center hospitals. Cancer 36 (1975) 2179-2191
3. Winkler K., Beron G., Kotz R., Salzer-Kuntschik M., Beck J., Beck W., Brandeis W., et al. Neoadjuvant chemotherapy for osteosarcoma: results of a cooperative German/Austrian study. J Clin Oncol 2 (1984) 617-624
4. French Bone Tumor Study Group. Age and dose of chemotherapy as major prognostic factors in a trial of adjuvant therapy of osteosarcoma combining two alternating drug combinations and early prophylactic lung irradiation. Cancer 61 (1988) 1304-1311
5. Bacci G., Longhi A., Bertoni F., Bacchini P., Ruggeri P., Versari M., and Picci P. Primary high-grade osteosarcoma: comparison between preadolescent and older patients. J Pediatr Hematol Oncol 27 (2005) 129-134
6. Cho W.H., Lee S.Y., Song W.S., and Park J.H. Osteosarcoma in preadolescent patients. J Int Med Res 34 (2006) 676-681
7. Rytting M., Pearson P., Raymond A.K., Ayala A., Murray J., Yasko A.W., Johnson M., et al. Osteosarcoma in preadolescent patients. Clin Orthop Relat Res 373 (2000) 39-50
8. Bacci G., Balladelli A., Palmerini E., Alberghini M., Pollastri P., Galletti S., Mercuri M., et al. Neoadjuvant chemotherapy for osteosarcoma of the extremities in preadolescent patients: the Rizzoli Institute experience. J Pediatr Hematol Oncol 30 (2008) 908-912
9. Lockitch G., Halstead A.C., Albersheim S., MacCallum C., and Quigley G. Age-and sex-specific pediatric reference intervals for biochemistry analyzes as measured on the Ektachem-700 analyzer. Clin Chem 34 (1988) 1622-1625
10. Bacci G., Briccoli A., Ferrari S., Longhi A., Mercuri M., Capanna R., Donati D., et al. Neoadjuvant chemotherapy for osteosarcoma of the extremity: long-term results of the Rizzoli's 4th protocol. Eur J Cancer 37 (2001) 2030-2039
11. Chen W.M., Chen T.H., Huang C.K., Chiang C.C., and Lo W.H. Treatment of malignant bone tumours by extracorporeally irradiated autograft-prosthetic composite arthroplasty. J Bone Joint Surg Br 84 (2002) 1156-1161
12. Chen T.H., Chen W.M., and Huang C.K. Reconstruction after intercalary resection of malignant bone tumours: comparison between segmental allograft and extracorporeally-irradiated autograft. J Bone Joint Surg Br 87 (2005) 704-709
13. Huang T.L., Chen T.H., Chen W.Y., Chen W.M., Liu C.L., and Lo W.H. Allograft arthrodesis of the knee in high-grade osteosarcoma. J Chin Med Assoc 68 (2005) 425-430
14. Hung G.Y., Chiou T., Hsieh Y.L., Yang M.H., and Chen W.Y. Intestinal metastasis causing intussusception in a patient treated for osteosarcoma with history of multiple metastases: a case report. Jpn J Clin Oncol 31 (2001) 165-167
15. Hung M.C., Hung G.Y., Lin P.C., Tiu C.M., and Tien Y.C. Acute pancreatitis associated with ifosfamide. J Chin Med Assoc 70 (2007) 176-179
16. Lin M.T., Lin K.H., Lin D.T., Yang R.S., Wu C.T., Lu M.Y., Hung I.J., et al. Unstratified chemotherapy for non-metastatic osteosarcoma of the extremities in children. J Formos Med Assoc 102 (2003) 387-393
17. Mirabello L., Troisi R.J., and Savage S.A. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 115 (2009) 1531-1543
18. Neel M.D., Wilkins R.M., Rao B.N., and Kelly C.M. Early multicenter experience with a noninvasive expandable prosthesis. Clin Orthop Relat Res 415 (2003) 72-81
19. Rao B.N., and Rodriguez-Galindo C. Local control in childhood extremity sarcomas: salvaging limbs and sparing function. Med Pediatr Oncol 41 (2003) 584-587
20. Lewis I.J., Nooij M.A., Whelan J., Sydes M.R., Grimer R., Hogendoorn P.C., Memon M.A., et al. Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: a randomized phase III trial of the European Osteosarcoma Intergroup. J Natl Cancer Inst 99 (2007) 112-128
21. Eselgrim M., Grunert H., Kühne T., Zoubek A., Kevric M., Bürger H., Jürgens H., et al. Dose intensity of chemotherapy for osteosarcoma and outcome in the Cooperative Osteosarcoma Study Group (COSS) trials. Pediatr Blood Cancer 47 (2006) 42-50
22. Bacci G., Mercuri M., Longhi A., Ferrari S., Bertoni F., Versari M., and Picci P. Grade of chemotherapy-induced necrosis as a predictor of local and systemic control in 881 patients with non-metastatic osteosarcoma of the extremities treated with neoadjuvant chemotherapy in a single institution. Eur J Cancer 41 (2005) 2079-2085
23. Sami S.H., Rafati A.H., and Hodjat P. Tissue necrosis after chemotherapy in osteosarcoma as the important prognostic factor. Saudi Med J 29 (2008) 1124-1129
24. Rosen G., Marcove R.C., Caparros B., Nirenberg A., Kosloff C., and Huvos A.G. Primary osteogenic sarcoma: the rationale for preoperative chemotherapy and delayed surgery. Cancer 43 (1979) 2163-2177
25. Bramer J.A., Abudu A.A., Tillman R.M., Carter S.R., Sumathi V.P., and Grimer R.J. Pre-and post-chemotherapy alkaline phosphatase levels as prognostic indicators in adults with localized osteosarcoma. Eur J Cancer 41 (2005) 2846-2852
26. Sauerbrey A., Bielack S., Kempf-Bielack B., Zoubek A., Paulussen M., and Zintl F. High-dose chemotherapy (HDC) and autologous hematopoietic stem cell transplantation (ASCT) as salvage therapy for relapsed osteosarcoma. Bone Marrow Transplant 27 (2001) 933-937
27. Chou A.J., Geller D.S., and Gorlick R. Therapy for osteosarcoma: where do we go from here?. Paediatr Drugs 10 (2008) 315-327