Does splenic preservation treatment (embolization, splenorrhaphy, and partial splenectomy) improve immunologic function and long-term prognosis after splenic injury?

Journal of Trauma - Injury, Infection and Critical Care

Volumn 67, Issue 3, 2009, Pages 557-563

  Nakae, Haruhiko ^a   Shimazu, Takeshi ^a   Miyauchi, Hiroshi ^b   Morozumi, Junya ^c   Ohta, Shoichi ^c   Yamaguchi, Yoshihiro ^b   Kishikawa, Masanobu ^d   Ueyama, Masashi ^e   Kitano, Mitsuhide ^f   Ikeuchi, Hisashi ^g   Yukioka, Tetsuo ^c   Sugimoto, Hisashi ^h  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYORIN UNIVERSITY   (Japan)

^c TOKYO MEDICAL UNIVERSITY HOSPITAL   (Japan)

^d SAISEIKAI FUKUOKA GENERAL HOSPITAL   (Japan)

^e CHUKYO HOSPITAL   (Japan)

^f KEIO UNIVERSITY   (Japan)

^g OSAKA GENERAL MEDICAL CENTER   (Japan)

^h OSAKA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Anti Streptococcus pneumoniae IgG antibodies; Howell Jolly body; IgM; Spleen; Trauma

Indexed keywords

BACTERIAL POLYSACCHARIDE; BACTERIUM ANTIBODY; C REACTIVE PROTEIN; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C5; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY;

ABDOMINAL BLUNT TRAUMA; ADULT; ARTICLE; ARTIFICIAL EMBOLISM; B LYMPHOCYTE; BLOOD ANALYSIS; BLOOD SAMPLING; CELLULAR IMMUNITY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HOSPITALIZATION; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; INFECTION; INTERMETHOD COMPARISON; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTHROMBIN TIME; SEROTYPE; SPLEEN FUNCTION; SPLEEN INJURY; SPLENECTOMY; SPLENORRHAPHY; STREPTOCOCCUS PNEUMONIAE; SUTURING METHOD; T LYMPHOCYTE; TREATMENT OUTCOME; ANTIBODY PRODUCTION; BLUNT TRAUMA; CLINICAL TRIAL; COHORT ANALYSIS; CONVALESCENCE; IMMUNOLOGY; INJURY; MIDDLE AGED; MULTICENTER STUDY; PHYSIOLOGY; RETROSPECTIVE STUDY; SPLEEN;

ADULT; ANTIBODY FORMATION; COHORT STUDIES; EMBOLIZATION, THERAPEUTIC; FEMALE; HUMANS; IMMUNITY, CELLULAR; MALE; MIDDLE AGED; PROGNOSIS; RECOVERY OF FUNCTION; RETROSPECTIVE STUDIES; SPLEEN; SPLENECTOMY; WOUNDS, NONPENETRATING; YOUNG ADULT;

EID: 70449135287     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3181af6ca9     Document Type: Article

References (29)

1. King H, Schumacher HB Jr. Splenic studies. I. Susceptibility to infection after splenectomy performed in infancy. Ann Surg. 1952; 136:239-242.
2. Sherman R. Perspective in management of trauma to the spleen: 1979 presidential address, American Association for the Surgery of Trauma. J Trauma. 1980;20:1-13.
3. Peitzman AB, Heil B, Rivera L, et al. Blunt splenic injury in adults: Multi-institutional Study of the Eastern Association for the Surgery of Trauma. J Trauma. 2000;49:177-187.
4. Claret I, Morales L, Montaner A. Immunological studies on the postsplenectomy syndrome. J Pediatr Surg. 1975;10:59-64.
5. Chaimoff C, Douer D, Pick IA, Pinkhas J. Serum immunoglobulin changes after accidental splenectomy in adults. Am J Surg. 1978;136:332-333.
6. Downey EC, Shackford SR, Fridlund PH, Ninnemann JL. Long-term depressed immune function in patients splenectomized for trauma. J Trauma. 1987;27:661-663.
7. Carlisle HN, Saslaw S. Properdin levels in splenectomized persons. Proc Soc Exp Biol Med. 1959;102:150-154.
8. Constantopoulos A, Nijjar VA, Wish JB, Necheles TH, Stolbach LL. Defective phagocytosis due to tuftsin deficiency in splenectomized subjects. Am J Dis Child. 1973;125:663-665.
9. Di Padve F, Dürig M, Harder F, Di Padova C, Zanussi C. Impaired antipneumococcal antibody production in patients without spleens. Br Med J. 1985;290:14-16.
10. Landesman SH, Schiffman G. Assessment of the antibody response to pneumococcal vaccine in high-risk populations. Rev Infect Dis. 1981;3: S184-S197.
11. Caplan ES, Boltansky H, Snyder MJ, et al. Response of traumatized splenectomized patients to immediate vaccination with polyvalent pneumococcal vaccine. J Trauma. 1983;23:801-804.
12. Schwartz AD, Goldthorn JF, Winkelstein JA, Swift AJ. Lack of protective effect of autotransplanted splenic tissue to pneumococcal challenge. Blood. 1978;51:475-478.
13. Traub A, Giebink GS, Smith C, et al. Splenic reticuloendothelial function after splenectomy, spleen repair, and spleen autotransplantation. N Engl J Med. 1987;317:1559-1564.
14. Falimirski M, Syed A, Prybilla D. Immunocompetence of the severely injured spleen verified by differential interference contrast microscopy: the red blood cell pit test. J Trauma. 2007;63:1087-1092.
15. Resende V, Petroianu A, Junior WC. Autotransplantation for treatment of severe splenic lesions. Emerg Radiol. 2002;9:208-212.
16. Corazza GR, Tarozzi C, Viara D, Frisoni M, Gasbarrini G. Return of splenic function after splenectomy: how much tissue is needed. Br Med J. 1984;189:861-864.
17. JAST committee on classification of splenic injury: Splenic injury classification. J Jpn Assoc Surg Trauma. 1997;11:30. (In Japanese).
18. Specialty Laboratories. Pneumo-7™: Immunization efficacy of the heptavalent pneumococcal vaccine. Available at: http://www.specialtylabs. com/education/download-PDF/TN-11801.pdf. Accessed August 31, 2008.
19. Bessoud B, Duchosal MA, Siegrist CA, et al. Proximal splenic artery embolization for blunt splenic injury: clinical, immunologic, and ultrasound- doppler follow-up. J Trauma. 2007;62:1481-1486.
20. Concepcion N, Frasch CE. Evaluation of previously assigned antibody concentrations in pneumococcal polysaccharide reference serum 89SF by the method of cross-standardization. Clin Diagn Lab Immunol. 1998;5:199-214.
21. Sorensen RU, Leiva LE, Giangrosso PA, et al. Response to heptavalent conjugate Streptococcus pneumoniae vaccine in children with recurrent infections who are unresponsive to the polysaccharide vaccine. Pediatr Infect Dis J. 1998;17:685-691.
22. Ockene IS, Matthews CE, Rifai N, Ridker PM, Reed G, Stanek E. Variability and classification accuracy of serial high-sensitivity Creactive protein measurements in healthy adults. Clin Chem. 2001; 47:444-450.
23. Ridker PM. High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease. Circulation. 2001;103:1813-1818.
24. Demeter J, Bohm U, Paloczi K, Lehoczky D, Merétey K. Immunoglobulin profiles and antibacterial antibody levels in 50 patients a long time after posttraumatic splenectomy. J Clin Lab Immunol. 1990;22:7-9.
25. Shimazu T, Tabata T, Tanaka H, et al. Immunologic alterations after splenectomy for trauma. Nippon Geka Gakkai Zasshi. 1995;96:36-43. (In Japanese with abstract in English).
26. Waghorn DJ, Mayon-White RT. A study of 42 episodes of overwhelming post-splenectomy infection: is current guidance for asplenic individuals being followed? J Infect. 1997;35:289-294.
27. Shatz DV. Vaccination practices among North American trauma surgeons in splenectomy for trauma. J Trauma. 2002;53:950-956.
28. Moore GE, Stevens RE, Moore EE, Aragon GE. Failure of splenic implant to protect against fatal postsplenectomy infection. Am J Surg. 1983;146:413-414.
29. Sass W, Bergholz, Kehl A, Seifert J, Hamelmann H. Overwhelming infection after splenectomy in spite of some spleen remaining and splenosis. A case report. Klin Wochenschr. 1983;61:1075-1079.