A study of 42 episodes of overwhelming post-splenectomy infection: Is current guidance for asplenic individuals being followed?

Journal of Infection

Volumn 35, Issue 3, 1997, Pages 289-294

  Waghorn, D J ^a   Mayon White, R T ^b  

^a WYCOMBE HOSPITAL   (United Kingdom)

^b Oxfordshire Dept of Public Health   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; PNEUMOCOCCUS VACCINE;

ADOLESCENT; ADULT; AGED; ANAMNESIS; ARTICLE; ASPLENIA; BACTERIAL INFECTION; CHEMOPROPHYLAXIS; CHILD; DATA ANALYSIS; DRUG SELF ADMINISTRATION; FOLLOW UP; HEALTH SURVEY; HIGH RISK PATIENT; HUMAN; IMMUNIZATION; INFANT; INFECTION RISK; MAJOR CLINICAL STUDY; MEDICAL SPECIALIST; MICROBIOLOGY; MORTALITY; NEWBORN; ONSET AGE; PATIENT EDUCATION; POSTOPERATIVE INFECTION; PRACTICE GUIDELINE; PROPHYLAXIS; REVACCINATION; SPLEEN; SPLENECTOMY; STREPTOCOCCUS INFECTION; SURGICAL PATIENT; VACCINATION;

EID: 0031440224     PISSN: 01634453     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-4453(97)93232-1     Document Type: Article

References (30)

1. Jenks PJ, Jones E. Infections in asplenic patients. Clin Micro Infect 1996; 1: 266-272.
2. McMullin M, Johnston G. Long term management of patients after splenectomy. BMJ 1993; 307: 1372-1373.
3. Reid MM. Splenectomy, sepsis, immunisation, and guidelines. Lancet 1994; 344: 970-971.
4. Flegg PJ. National guidelines, please. BMJ 1994; 308: 131.
5. Obaro SK, Henderson DC, Monteil M. Immunity to pneumococcal infections. Lancet 1995; 345: 70-71.
6. Baddeley P, Boyer P, Mayon-White R. Fact sheets, posters, and protocol cards available. BMJ 1994; 308: 132.
7. Department of Health. Asplenic patients and immunisation. CMO's Update 1994; 1: 3.
8. MacInnes J, Waghorn DJ, Haworth E. Management of asplenic patients in South Buckinghamshire: an audit of local practice. Public Health Laboratory Service CDR Review 1995; 5: R173-R177.
9. Long SG, Smith AG, Perry BA, Leyland MJ, Milligan DW. Implementing a policy for pneumococcal prophylaxis in a haematology unit after splenectomy. Quality in Health Care 1995; 4: 194-196.
10. Working Party of the British Committee for Standards in Haematology Clinical Haematology Task Force. Guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen. BMJ 1996; 312: 430-434.
11. Anonymous. Surveillance of overwhelming infection following splenectomy. Public Health Laboratory Service CDR Weekly 1994; 4: 169.
12. Anonymous. Overwhelming infection following splenectomy. Scottish Centre for Infection and Environmental Health SCIEH Weekly Report 1995; 29: 1.
13. Shaw JH, Print CG. Postsplenectomy sepsis. Br J Surg 1989; 76: 1074-1081.
14. McKay PJ, Kennedy DH, Lucie NP. Should hyposplenic patients receive prophylaxis against bacterial infection? Scot Med J 1993; 38: 51-52.
15. Muller AF, Toghill PJ. Hyposplenic patients need prophylactic penicillin. BMJ 1994; 308: 132-133.
16. Fielding AK. Prophylaxis against late infection following splenectomy and bone marrow transplant. Blood Reviews 1994; 8: 179-191.
17. Van Wyke DB. Overwhelming post-splenectomy infection (OPSI): the clinical syndrome. Lymphology 1983; 16; 107-114.
18. Abildgaard N, Nielsen JL. Pneumococcal septicaemia and meningitis in vaccinated splenectomised adult patients. Scand J Infect Dis 1994; 26: 615-617.
19. Hazlewood M, Kumararatne DS. The spleen. Who needs it anyway? Clin Exp Immunol 1992; 89: 327-329.
20. Konradsen HB, Pedersen FK, Henrichsen J. Pneumococcal revaccination of splenectomized children. Pediatr Infect Dis J 1990; 9: 258-263.
21. Konradsen HB. The need for revaccination 10 years after primary pneumococcal vaccination in splenectomized adults. Scand J Infect Dis 1991; 23: 397.
22. Kassianos GC. Uncertainty exists over frequency of blood tests to test antipneumococcal immunity. BMJ 1996; 312: 1360-1361.
23. Anonymous. Splenectomy - a long-term risk of infection. Lancet 1985; ii: 928-929.
24. Holdsworth RJ, Irving AD, Cuschieri A. Postsplenectomy sepsis and its mortality rate: actual versus perceived risks. Br J Surg 1991; 78: 1031-1038.
25. Spelman DW. Postsplenectomy overwhelming sepsis: reducing the risks. Med J Aust 1996; 164: 648.
26. Read RC, Finch RG. Prophylaxis after splenectomy. J Antimicrob Chemother 1994; 33: 4-6.
27. Finch RG, Read R. Lifelong penicillin may be ineffective. BMJ 1994; 308: 132.
28. Waghorn DJ. Prevention of postsplenectomy sepsis. Lancet 1993; 341: 248.
29. Deodhar HA, Marshall RJ, Barnes JN. Increased risk of sepsis after splenectomy. BMJ 1993; 307: 1408-1409.
30. Makris M, Greaves M, Winfield DA, Preston FE, Lilleyman JS. Lifelong penicillin unproved in trials. BMJ 1994; 308: 131-132.