Tumour tracking with scanned proton beams: Assessing the accuracy and practicalities

Physics in Medicine and Biology

Volumn 54, Issue 21, 2009, Pages 6549-6563

  Van De Water, S ^a,b   Kreuger, R ^b   Zenklusen, S ^a   Hug, E ^a   Lomax, A J ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DOSE CALCULATION; HYBRID SOLUTION; IN-SILICO; MOTION PHASIS; MOVING TARGETS; PENCIL BEAM; POSITION ERRORS; PREDICTION ERRORS; PROTON THERAPY; RE-TRACKING; TARGET MOTIONS; TARGET POSITION; TARGET VOLUMES; TRACKING ALGORITHM; TRACKING MODE; TREATMENT OUTCOMES;

ERRORS; PROTON BEAMS; PROTONS; TARGETS; TIME DELAY; TUMORS;

TARGET TRACKING;

ARTICLE; DOSIMETRY; PRIORITY JOURNAL; PROTON THERAPY; RADIATION BEAM; RADIATION DOSE; TREATMENT PLANNING; TUMOR SCINTISCANNING;

ALGORITHMS; COMPUTER SIMULATION; HUMANS; MODELS, STATISTICAL; MODELS, THEORETICAL; MONTE CARLO METHOD; MOTION; NEOPLASMS; PHANTOMS, IMAGING; PROTONS; RADIATION DOSAGE; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

EID: 70449120374     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/54/21/007     Document Type: Article

References (31)

1. Ares C, Hug E B, Lomax A J, Bolsi A, Timmermann B, Rutz H P, Schuller J C, Pedroni E and Goitein G 2009 Effectiveness and safety of spot scanning proton radiation therapy for chordomas and chondrosarcomas of the skull base: first long term report Int. J. Radiat. Oncol. Biol. Phys. (Apr. 20, Epub ahead of print)
2. Bert C, Grözinger S O and Rietzel E 2008 Quantification of interplay effects of scanned particle beams and moving targets Phys. Med. Biol. 53 2253-65
3. Bert C and Rietzel E 2007 4D treatment planning for scanned ion beams Radiat. Oncol 2 24
4. Bert C, Saito N, Schmidt A, Chaudhri N, Schardt D and Rietzel E 2007 Target motion tracking with a scanned particle beam Med. Phys. 34 4768-71
5. Bortfeld T, Jokivarsi K, Goitein M, Kung J and Jiang S B 2002 Effects of intra-fraction motion on IMRT dose delivery: statistical analysis and simulation Phys. Med. Biol. 47 2203-20
6. Boyer A L, Goitein M, Lomax A J and Pedroni E S 2002 Radiation in the treatment of cancer Phys. Today 34-6
7. Eickhoff H, Haberer T, Kraft G, Krause U, Richter M, Steiner R and Debus J 1999 The GSI cancer therapy project Strahlenther. Onkol. 175 (Suppl. 2) 21-4
8. George R, Vedam S S, Chung T D, Ramakrishnan V and Keall P J 2005 The application of the sinusoidal model to lung cancer patient respiratory motion Med. Phys 32 2850-61
9. Grözinger S O, Bert C, Haberer T, Kraft G and Rietzel E 2008 Motion compensation with a scanned ion beam: a technical feasibility study Radiat. Oncol. 3 34
10. Grözinger S O, Li Q, Rietzel E, Haberer T and Kraft G 2004 3D online compensation of target motion with scanned particle beam Radiother. Oncol. 73 (Suppl. 2) S77-9
11. Grözinger S O, Rietzel E, Li Q, Bert C, Haberer T and Kraft G 2006 Simulations to design an online motion compensation system for scanned particle beams Phys. Med. Biol. 51 3517-31
12. Hoogeman M, Prévost J B, Nuyttens J, Pöll J, Levendag P and Heijmen B 2009 Clinical accuracy of the respiratory tumor tracking system of the CyberKnife: assessment by analysis of log files Int. J. Radiat. Oncol. Biol. Phys. 74 297-303
13. Keall P J, Cattell H, Pokhrel D, Dieterich S, Wong K H, Murphy M J, Vedam S S, Wijesooriya K and Mohan R 2006a Geometric accuracy of a real-time target tracking system with dynamic multileaf collimator tracking system Int. J. Radiat. Oncol. Biol. Phys. 65 1579-84
14. Keall P, Vedam S, George R, Bartee C, Siebers J, Lerma F, Weiss E and Chung T 2006b The clinical implementation of respiratory-gated intensity-modulated radiotherapy Med. Dosim. 31 152-62
15. Lomax A J 1999 Intensity modulated methods for proton therapy Phys. Med. Biol. 44 185-205
16. Lomax A J et al 2004 Treatment planning and verification of proton therapy using spot scanning: initial experiences Med. Phys. 31 3150-7
17. Lomax A J et al 2001 Intensity modulated proton therapy: a clinical example Med. Phys. 28 317-24
18. Lujan A E, Larsen E W, Balter J M and Ten Haken R K 1999 A method for incorporating organ motion due to breathing into 3D dose calculations Med. Phys. 26 715-20
19. Papiez L, Rangaraj D and Keall P 2005 Real-time DMLC IMRT delivery for mobile and deforming targets Med. Phys. 32 3037-48
20. Pedroni E et al 1995 The 200 MeV proton therapy project at PSI: conceptual design and practical realisation Med. Phys. 22 37-53
21. Pedroni E et al 2004 The PSI Gantry 2: a second generation proton scanning gantry Z. Med. Phys. 14 25-34
22. Phillips M H, Pedroni E, Blattmann H, Boehringer T, Coray A and Scheib S 1992 Effects of respiratory motion on dose uniformity with a charged particle scanning method Phys. Med. Biol. 37 223-34
23. Rutz H P, Weber D C, Goitein G, Ares C, Bolsi A, Lomax A J, Pedroni E, Coray A, Hug E B and Timmermann B 2008 Postoperative spot-scanning proton radiation therapy for chordoma and chondrosarcoma in children and adolescents: initial experience at Paul Scherrer Institute Int. J. Radiat. Oncol. Biol. Phys. 71 220-5
24. Schaffner B, Pedroni E and Lomax A J 1999 Dose calculation models for proton treatment planning using a dynamic beam delivery system: an attempt to include density heterogeneity effects in the analytical dose calculation Phys. Med. Biol. 44 27-42
25. Schulz-Ertner D, Nikoghosyan A, Thilmann C, Haberer T, Jäkel O, Karger C, Kraft G, Wannenmacher M and Debus J 2004 Results of carbon ion radiotherapy in 152 patients Int. J. Radiat. Oncol. Biol. Phys. 58 631-40
26. Seiler P G, Blattmann H, Kirsch S, Muench R K and Schilling C 2000 A novel tracking technique for the continuous precise measurement of tumour positions in conformal radiotherapy Phys. Med. Biol. 45 N103-10
27. Vedam S S, Keall P J, Docef A, Todor D A, Kini V R and Mohan R 2004 Predicting respiratory motion for four-dimensional radiotherapy Med. Phys. 31 2274-83
28. von Siebenthal M 2008 Analysis and modelling of respiratory liver motion using 4DMRI ETH Dissertation No. 17613
29. von Siebenthal M, Cattin P, Lomax A J, Boesiger P and Székely G 2007 4D MRI imaging of respiratory organ motion and its variability Phys. Med. Biol. 52 1547-64
30. Weber D C, Rutz H P, Pedroni E, Bolsi A, Timmermann B, Verwey J, Lomax A J and Goitein G 2005 Results of spot-scanning proton radiation therapy for chordoma and chondrosarcoma of the skull-base: the Paul Scherrer Institute experience Int. J. Radiat. Oncol. Biol. Phys. 63 401-9
31. Wilson R R 1946 Radiological use of fast protons Radiology 47 487-91